CAS: 15307-86-5; 2-(2-((2,6-Dichlorophenyl)Amino)Phenyl)Acetic Acid

上下游产品

CAS号21789-06-0 2-[(2,6-Dichlor... | CAS号15307-79-6 双氯芬酸钠 | CAS号70690-44-7 2-[(2,6-dichlor... | CAS号7732-18-5 水 | CAS号95-50-1 邻二氯苯 | CAS号608-31-1 2,6-二氯苯胺 | CAS号83281-95-2 2-[(2,6-dichlor... | CAS号30124-09-5 2-[2-(2,6-dichl... | CAS号69002-84-2 2-[(2,6-二氯苯基)氨基... | CAS号64118-84-9 2-((2,6-二氯-4-羟基... | CAS号15307-78-5 2-(2,6-二氯苯胺基)苯乙酸甲酯 | CAS号15362-40-0 双氯芬酸钠杂质A | CAS号51998-02-8 pyridin-3-yl 2-...

2-[(2,6-二氯苯基)氨基]-N,N-二甲基苯乙酰胺置于氢氧化钾体系中,用 乙醇,水 用作溶剂,以92.9%的收率获得双氯芬酸
参考文献:Process For Preparation Of O-(2,6-Dichloroanilino)Phenylacetic Acid And
标题:Process For Preparation Of O-(2,6-Dichloroanilino)Phenylacetic Acid And
摘要:披露了一种制备o-(2,6-二氯苯胺基)苯乙酸(双氯芬酸)或其药理学上可接受的酸盐的方法,该方法包括用碱水解n,N-二取代的o-(2,6-二氯苯胺基)苯乙酰胺衍生物.还披露了一种用于制备双氯芬酸的新中间体,即n,N-二取代的o-卤代苯乙酰胺,其中卤素是碘或溴.

专利信息

专利号:US-7692019-B2
优先权日:2000-12-04
标 题:Methods for the stereoselective synthesis of substituted piperidines
发明人：AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HEFFERNAN MICHELE L R; HOEMANN MICHAEL Z; KESSLER DONALD W; SHAO LIMING; WU XINHE; XIE ROGER L
权利人:SEPRACOR INC
摘要:One aspect of the present invention relates to methods of synthesizing substituted piperidines. A second aspect of the present invention relates to stereoselective methods of synthesizing substituted piperidines. The methods of the present invention will find use in the synthesis of compounds useful for treatment of numerous ailments, conditions and diseases that afflict mammals, including but not limited to addiction and pain. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the substituted piperidines using the methods of the present invention. An additional aspect of the present invention relates to enantiomerically substituted pyrrolidines, piperidines, and azepines.

专利号:US-2012177593-A1
优先权日:2009-07-20
标 题 :Synthesis of dendrimer conjugates
发明人：BAKER JR JAMES R; ZHANG YUEHUA; THOMAS THOMMEY P; DESAI ANKUR MAHESH
权利人:BAKER JR JAMES R; ZHANG YUEHUA; THOMAS THOMMEY P; DESAI ANKUR MAHESH; UNIV MICHIGAN
摘要:The present invention relates to novel methods of synthesis of therapeutic and diagnostic dendrimers. In particular, the present invention is directed to novel dendrimer conjugates, novel methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer, inflammatory disease) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer conjugates of the present invention may further comprise at least two different components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy. Furthermore, the novel synthesis methods of certain embodiments of the present invention provide significant advantages with regard to total reaction time and simplicity.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-2023192819-A1
优先权日:2022-03-28
标题 :Ultrafast synthesis of holey and wrinkled graphene
发明人：TOUR JAMES M; WYSS KEVIN
权利人:UNIV RICE WILLIAM M
摘要:Ultrafast synthesis of holey and wrinkled graphene and compositions thereof, and more particularly, ultrafast synthesis of holey and wrinkled graphene from carbon material, such as plastic waste via a flashing joule heating process and compositions thereof or using higher surface area materials like high surface area carbon black, activated charcoal, or biochar as starting materials with a salt additive.

专利号:US-6653468-B1
优先权日:2002-07-31
标 题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-5043328-A
优先权日:1986-05-09
标 题 :Formulations containing unsaturated fatty acids for the synthesis of prostaglandins and hydroxy-fatty acids in biological systems
发明人：WEITHMANN KLAUS U
权利人:HOECHST AG
摘要:The present invention relates to formulations containing unsaturated fatty acids for the synthesis of prostaglandins and hydroxy-fatty acids in biological systems and to the use of such formulations for the preparation of medicaments which are suitable for curing prostaglandin deficiencies in humans or animal, for example healing or preventing diseases of the gastro-intestinal tract.