CAS: 134363-45-4; 2-(Pyridin-3-yl)Benzoic Acid

相似化合物

176690-44-1 1238617-38-3 857284-03-8

上下游产品

2-(pyridin-3-yl)benzonitrile 3-(o-carbomethoxyphenyl)pyridine 3-Bromopyridine 2-carboxyphenylboronic acid 3-(o-carbomethoxyphenyl)pyridine 2-Pyridin-3-yl-benzoyl chloride nicotinic acid 3-phenylpyridine

📜二乙基(3-吡啶基)-硼烷置于氢氧化钾,四(三苯基膦)钯,四丁基溴化铵体系中,用 四氢呋喃,乙醇 用作溶剂,化学反应 36.0H,反应生成2-(3-吡啶)苯甲酸
参考文献:Inhibition Of Myeloperoxidase Release From Rat Polymorphonuclear Leukocytes By A Series Of Azachalcone Derivatives
标题:Inhibition Of Myeloperoxidase Release From Rat Polymorphonuclear Leukocytes By A Series Of Azachalcone Derivatives
摘要:A Series Of Azachalcones Was Evaluated For Ability To Affect Secretion Of Myeloperoxidase By Rat Polymorphonuclear Leukocytes Stimulated By Fmlp. The Compounds Were Found To Interfere With Cellular Uptake Of Extracellular Calcium. Structure-Activity Relationships Are Discussed.
Doi:10.1021/jm00051A013

专利信息

专利号:US-8017786-B2
优先权日:2006-05-15
标 题:Substituted β-phenyl-α-hydroxy-propanoic acid, synthesis method and use thereof
发明人：ZHENG XIAOHUI; ZHANG QUNZHENG; WANG SHIXIANG; ZHAO XINFENG
权利人:UNIV NORTHWEST
摘要:The present invention relates to a compound of the formula (I), wherein R 1 , R 2 and R 3 are each independently selected from H, OH, F, Cl, Br, methoxy and ethoxy; or alternatively, R 1 and R 2 together form —OCH 2 O—, R 3 is selected from H, OH, methoxy, ethoxy and halogens; R 4 is OH or acyloxy; R 5 is cycloalkoxyl, amino and substituted amino, and when R 5 is selected from amino, at least one of R 1 , R 2 and R 3 is not H. The present invention further relates to a process for synthesizing a compound of the formula (I), and use of the compound of the formula (I) in the manufacture of a medicament for the prevention or treatment of cardiovascular or cerebrovascular diseases.