CAS: 129460-09-9; Fmoc-Asp-Otbu

相似化合物

134098-70-7 34582-32-6 77004-75-2

上下游产品

CAS号150009-58-8 N-Fm°C-D-天冬氨酸-4-苄酯 | CAS号56-84-8 L-天门冬氨酸 | CAS号102774-86-7 (9H-芴-9-基)甲基 2,... | CAS号115-11-7 2-甲基丙烯 | CAS号4125-93-3 L-天冬氨酸叔丁脂 | CAS号136083-57-3 Fm°C-D-天冬氨酸 | CAS号131287-39-3 Fm°C-L-Asn(GlcN...

芴甲氧羰基-天冬氨酸-β苄脂置于palladium On Activated Charcoal 吡啶,氢气,三氯氧磷体系中,化学反应生成芴甲氧羰基-L-天冬氨酸-1-叔丁酯
参考文献:A Convenient Preparation Of Several N-Linked Glycoamino Acid Building Blocks For Efficient Solid-Phase Synthesis Of Glycopeptides
标题:A Convenient Preparation Of Several N-Linked Glycoamino Acid Building Blocks For Efficient Solid-Phase Synthesis Of Glycopeptides
摘要:本研究提出了一条便捷且产率高的制备多个boc和fmoc保护的n-连接糖肽单体的方法.这些构建单元可用于糖肽或糖肽模拟物的固相合成,通过制备n-连接的十二糖肽ac-(Glyproasn[gal])4-nh2为例,展示了其作为潜在胶原蛋白模拟物的应用.
Doi:10.1039/b201296K

专利信息

专利号:US-2024067694-A1
优先权日:2021-01-04
标 题:Synthesis of teduglutide
发明人：GANGA RAMU VASANTHAKUMAR; PATIL NITIN; SUVARNA DEEPA SHANKAR
权利人:BIOCON LTD
摘要:The present invention provides for novel synthetic approach of solid phase synthesis of peptides with C-terminal Aspartic acid by anchoring the side chain carboxylic group of aspartic acid to the solid support to avoid the formation of various impurities and thus resulting in higher yield and ease the purification process. The present invention further provides the usage of free amino acids and reducing agents as antioxidants in the cleavage cocktail to negate the formation of oxidative impurities formed during the global cleavage and isolation of the peptide from solid support.

专利号:EP-1891104-B1
优先权日:2005-05-04
标题:Solid phase bound thymosin alpha1 and its synthesis
发明人：ALBERICIO FERNANDO; CRUZ LUIS JAVIER; GARCIA RAMOS YESICA; TULLA-PUCHE JUDIT
权利人:LONZA AG
摘要:A method for solid phase synthesis of Thymosin alpha1 is devised.

专利号:US-5175146-A
优先权日:1989-12-05
标题 :Synthetic calcitonin peptides
发明人：BASAVA CHANNA; HOSTETLER KARL Y
权利人:VICAL INC
摘要:Synthetic hypocalcemic peptides which are similar in biological properties to native calcitonins as clinically useful agents. The peptides comprise analogues of native calcitonins having amino acid substitutions and deletions which act to improve potency, prolong duration of the hormonal effect, enhance receptor binding, and increase oral or nasal bioavailability. The calcitonin peptide analogues are less expensive and more easily synthesized than native calcitonins, and have improved resistance to inactivation or degradation. Methods are provided for the synthesis of these peptides. Also, disclosed are novel cyclic peptides, including calcitonin, having increased stability with respect to proteolysis. Methods for the synthesis of these peptides are provided, comprising converting disulfide cyclic peptides and proteins to enzymatically and chemically stable cyclic peptide structures by the replacement of cysteine residues with dicarboxylic acids and diamino acids. The method is applicable to various naturally occurring peptides, their synthetic analogues or derivatives, and proteins.

专利号:US-12129277-B2
优先权日:2018-12-14
标 题 :Linear solution phase routes for WNT hexapeptides
发明人：VEERABHADRA PRATAP TADIKONDA; RAGHAVENDRA RAO KAMARAJU; HENRIKSEN DENNIS
权利人:WNTRESEARCH AB
摘要:The present disclosure relates generally to the field of polypeptide synthesis, and more particularly, to a linear solution phase synthesis of the Wnt hexapeptide Foxy-5 and protected derivatives and peptide fragments thereof.

专利号:US-11970551-B2
优先权日:2018-08-20
标题 :Solution phase routes for WNT hexapeptides
发明人：HENRIKSEN DENNIS
权利人:WNTRESEARCH AB
摘要:The present disclosure relates generally to the field of polypeptide synthesis, and more particularly, to the solution phase synthesis of the Wnt hexapeptide Foxy-5 and protected derivatives and peptide fragments thereof.

专利号:WO-2024028350-A1
优先权日:2022-08-01
标题 :Dipropylamine as base for the use in fmoc deprotection in solid-phase peptide synthesis
发明人：REYMOND JEAN-LOUIS; PERSONNE HIPPOLYTE; SIRIWARDENA THISSA N; JAVOR SACHA
权利人:UNIV BERN
摘要:The invention relates to a method for the preparation of peptides via solid-phase peptide synthesis and particularly to a method of deprotecting of an Fmoc protected amino acid building block linked to a resin R-AA-(AA)n-PF.