CAS: 114218-35-8; (-)-Metoprolol Hydrochloride

英文名称(-)-Metoprolol Hydrochloride
中文名称美托洛尔杂质18(单体)
CAS编号114218-35-8
分子式:C15H26ClNO3分子量:303.83
产品CID: 174630
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: UKBBZNRSHOCRNP-UQKRIMTDSA-N
1S/C15H25NO3.ClH/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;/h4-7,12,14,16-17H,8-11H2,1-3H3;1H/t14-;/m0./s1
计算化学: 氢键受体数4.0氢键供体数3.0可旋转键数9.0

物理性质

MSDS等安全信息

上下游产品

oxy>-2-oxo-1-propylamine hydr°ChlorideN-isopropyl-3-4'-(2''-methoxyethyl)phenyloxy-2-oxo-1-propylamine hydr°Chloride S-(-)-metoprolol 2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane (2S)-2-{[4-(2-Methoxyethyl)phenoxy]methyl}oxirane

合成工艺路线路线简述

56392-18-8 = 114218-35-8 + 68985-04-6
反应条件:1.1R:
标题:Synthesis And Application Of Clindamycin Succinate As A Novel Chiral Selector For Capillary Electrophoresis
作者:By Wu,Jianfeng Et Al
参考文献:Journal Of Separation Science 日期:2011 卷标:34(18) 页码:2455-2462

📜[[p-(2-甲氧基乙基)苯氧基]甲基]环氧乙烷置于盐酸体系中,用甲醇,水用作溶剂,化学反应 7.0H,反应生成美托洛尔杂质18(单体)
参考文献:Kinetic Resolution Of Aryl Glycidyl Ethers: A Practical Synthesis Of Optically Pure B-Blocker-s-Metoprolol
标题:Kinetic Resolution Of Aryl Glycidyl Ethers: A Practical Synthesis Of Optically Pure B-Blocker-s-Metoprolol
摘要:
Doi:10.3987/com-98-8169