CAS: 89415-43-0; (4-Aminophenyl)Boronic Acid
该化合物是一种有机化合物,其特征是存在一个氨基氨基化合物组和一个附属于一个苯环的碳酸性功能组,其分子结构中含有一个与氢氧基组结合的碳原子原子,以及一个也带有氨基氨基组的苯基环,该化合物一般是白色至白色固态的,可溶于水和酒精等极地溶液,可归因于其形成氢联结的能力. 4-氨基苯乙酸在药用化学和材料科学中的作用显著,特别是在开发用于交付药物的含有的化合物和作为有机合成的构件方面的作用,它可以参与各种化学反应,包括铃木联结,这对形成碳-碳联结具有重要意义.此外,复合物的特性使其与生物分子发生相互作用,使其对生物应用感兴趣,例如传感器或治疗剂的设计.
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;;;; - InChIKey: MKPDAJWEBQRQCO-UHFFFAOYSA-N
- InChI=1S/C6H8BNO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H,8H2
- 计算化学: 氢键受体数3.0氢键供体数3.0可旋转键数1.0
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CAS号106-47-8 对氯苯胺 | CAS号106-40-1 对溴苯胺 | CAS号64-17-5 乙醇 | CAS号214360-73-3 4-氨基苯硼酸频哪醇酯 | CAS号24067-17-2 4-硝基苯硼酸 | CAS号380430-49-9 4-(B°C-氨基)苯硼酸 | CAS号82261-42-5 4-(吡啶-3-基)苯胺 | CAS号123-30-8 对氨基苯酚 | CAS号1137-77-5 4-(4-甲氧基苯基)苯胺 | CAS号101251-09-6 4-乙酰胺基苯硼酸 | CAS号1204-79-1 4-氨基-4-羟基联苯 | CAS号1141-39-5 Ethanone,1-(4'-... | CAS号118727-34-7 1,3,5-三(4-氨苯基)苯合成工艺路线路线简述
- 796857-59-5 = 89415-43-0
反应条件:1.1 Reagents: Hydrogen,Hydrochloric Acid Catalysts: Azobisisobutyronitrile Solvents: Methanol,Water; 3 H,14 Bar,Rt
标题:4-Aminophenyl Boronic Acid Modified Gold Platforms For Influenza Diagnosis
作者:Diltemiz,Sibel Emir; Ersoz,Arzu; Hur,Deniz; Kecili,Rustem; Say,Ridvan
参考文献:Materials Science & Engineering 日期:2013 卷标:33(2) 页码:824-830
📜4-羧基苯硼酸置于氯化亚砜,盐酸羟胺,Sodium Methylate,Potassium Carbonate体系中,用 甲醇,乙腈 作为反应溶剂,化学反应 11.0H,反应生成 4-氨基苯硼酸
参考文献:一种氨基苯硼酸的制备方法
标题:一种氨基苯硼酸的制备方法
摘要:本发明公开了一种氨基苯硼酸的制备方法,属于有机合成技术领域.以羧基苯硼酸为原料,在氯化亚砜作用下酯化得到烷氧羰基苯硼酸,随后先将硫酸/盐酸羟胺在醇钠中游离,加入烷羰基苯硼酸中进行胺酯交换反应得到n‑羟基氨基甲酰基苯硼酸,随后洛森重排得到氨基苯硼酸.本发明工艺流程简单,总收率高达80‑85%,成本较低,反应条件温,对设备要求低,避免了超低温反应.
专利信息
专利号:WO-2023207921-A1
优先权日:2022-04-25
标题 :Taxamairin analogs and methods of preparation and use thereof
发明人：LEE CHI SING; GE SIYUAN; ZHUANG ANDREW-GO
权利人:UNIV HONG KONG BAPTIST UNIV
摘要:Taxamairin analogs useful in the treatment of cancer, pharmaceutical compositions including the same, methods of use thereof, and methods of preparation are provided. An efficient and scalable semi-synthesis of taxamairin compounds and analogs thereof from readily available commercial starting materials is provided. The synthesis involves low cost and relatively non-toxic reagents and is capable of synthesizing taxamairin A and taxamairin B and analogs thereof on multi-gram scale in yields up 12%and 21%, respectively.
专利号:US-2009227575-A1
优先权日:2008-03-04
标 题 :7H-PYRROLO[2,3-H]QUINAZOLINE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESIS
发明人：VENKATESAN ARANAPAKAM MUDUMBAI; CHEN ZECHENG; DOS SANTOS OSVALDO; BROOIJMANS NATASJA; GOPALSAMY ARIAMALA
权利人:WYETH CORP
摘要:A 7H-pyrrolo[2,3-h]quinazoline compound of the formula I n n n n n n n n n n wherein Ar, R 1 , R 2 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , and n are as defined in the specification, and methods for making same.
专利号:US-7585875-B2
优先权日:2006-06-06
标 题 :Substituted pyrazolo[1,5-a]pyridine compounds and their methods of use
发明人：GAETA FEDERICO C A; GROSS MATTHEW; JOHNSON KIRK W
权利人:AVIGEN INC
摘要:The present invention is directed to substituted pyrazolo[1,5-a]pyridines and related methods for their synthesis and use.
专利号:CN-113649067-B
优先权日:2021-08-13
标题:A kind of organic photocatalyst, preparation method and its application in the synthesis of 2,3,5-trimethylhydroquinone diester
专利号:US-2025026766-A1
优先权日:2022-01-12
标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors
发明人：LI JING; XU WENQING; WANG ZHIWEI
权利人:BEIGENE LTD
摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.
专利号:CN-114369031-B
优先权日:2021-12-24
标题:A kind of synthesis method of 4,4'-diaminoterphenyl
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Synthesis Of New Heteroaryl Substituted Morpholine Tagged Triazines And Evaluation Of Their Cytotoxic Activity作者:Sivaprasad Kasturi,Sujatha Surarapu,Srinivas Uppalanchi,Hasitha Shilpa Anantaraju,Shubham Dwivedi,Perumal Yogeeswari,Krishna S. Ethiraj,Jaya Shree Anireddy |发布日期:2018.1.30
摘要:Background: In The Present Study, New Triazine Derivatives 3, 4, 5, 6, 8 And 10 Were Synthesized Starting From Readily Available Cyanuric Chloride 1 Via Nucleophilic Displacement With Morpholine Followed By Suzuki Or Stille Coupling Reactions And Then The Thermal Displacement Of Chlorine Atom With Diverse Substituted Amines. Methods: All Synthesized Compounds Were Screened For Their Cytotoxic Activity
合成参考文献
摘要:Mérour, J.-Y.; Joseph, B., Science of Synthesis Knowledge Updates, (2016) 3, 391.
摘要:Campagne, J. M.; Leclerc, E., Science of Synthesis Knowledge Updates, (2020) 2, 163.
参考文献:10.1038/s41596-021-00574-6
摘要:Gao P, Wang D, Che C, Ma Q, Wu X, Chen Y, Xu H, Li X, Lin Y, Ding D, Lou X, Xia F. Regional and functional division of functional elements of solid-state nanochannels for enhanced sensitivity and specificity of biosensing in complex matrices. Nat Protoc. 2021 Sep;16(9):4201–26. doi: 10.1038/s41596-021-00574-6.
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