CAS: 504-08-5; 1,3,5-Triazine-2,4-Diamine

该化合物是有机化合物,其特点是三亚胺环状结构,由三氮原子和三碳原子组成;是白色晶状固体,在水中溶解,熔点高;美拉胺以其热稳定性和耐火性而著称,在各种应用中,特别是在树脂和塑料生产中,它非常有用;它通常用于生产甲胺-甲胺甲胺树脂,由于其耐久性和坚硬性,而用于制成层状,粘合剂和涂层;此外,三聚胺在农业部门用作富氮肥;然而,必须指出,三聚胺在高浓度中具有毒性,特别是在与健康风险相关的食品中使用.

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合成工艺路线路线简述

    📜2-氯-4,6-二氨基-1,3,5-三嗪置于palladium On Activated Charcoal,1,2-丙二醇体系中,化学反应生成 2,4-二氨基-1,3,5-三嗪
    参考文献:Foye; Weinswig,Journal Of The American Pharmaceutical Association (1912),1959,Vol. 48,P. 327
    标题:Foye; Weinswig,Journal Of The American Pharmaceutical Association (1912),1959,Vol. 48,P. 327

    专利信息


    专利号:US-4579946-A
    优先权日:1985-01-10
    标 题:Process for synthesis of 2-vinyl-4,6-diamino-S-triazine
    发明人:SAWA NATSUO; MASUDA TAKESHI
    权利人:SHIKOKU CHEM
    摘要:Disclosed is a process for the synthesis of 2-vinyl-4,6-diamino-S-triazine having the following structural formula: ##STR1## which comprises heating an imidazolyl-S-triazine compound represented by the following general formula: ##STR2## wherein R 1 stands for a hydrogen atom, a methyl group or an ethyl group, and R 2 stands for a hydrogen atom or a methyl group, or an isocyanuric acid-addition product thereof under reduced pressure in the presence of a polymerization inhibitor. n According to this process, 2-vinyl-4,6-diamino-S-triazine can be manufactured at a low cost on an industrial scale.

    专利号:US-12428385-B2
    优先权日:2022-05-19
    标 题:Composition of a lipophilic agent for solution phase synthesis of biomolecules
    发明人:LI YONGFU
    权利人:LI YONGFU; BROTIDE CORE LLC
    摘要:Disclosed is a lipophilic agent comprising a triazine core having lipophilic groups for organic synthesis. The lipophilic agent soluble in one system of solvent(s) wherein the lipophilic agent is participated in a chemical reaction but insoluble by adding a miscible poor solvent to change solution composition after the reaction completes. The lipophilic agent facilitates process improvement wherein practical operation only involves mixing with reactants in solution followed by precipitating with change of solution composition followed by filtering to obtain the precipitated solid, simplifying the purification by isolating the desired solid. The operation is reproducible along the progress in a multi-step synthesis, allowing pure intermediates and pure product as a solid to be rapidly obtained with ease and certainty. This invention can thus accelerate research and development of pharmaceutical biomolecules, representing a tremendous step forward for boosting productivity and greening chemical industry.

    专利号:US-8759584-B2
    优先权日:2007-12-14
    标 题 :Synthesis of biguanidines and triazines, and biguanidino-aluminium complexes as intermediates
    发明人:FORD MARK JAMES
    权利人:FORD MARK JAMES; BAYER CROPSCIENCE AG
    摘要:Compounds of formula (I) or salts thereof, n nin which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , X and Y are defined as in claim 1 , can be prepared by a process characterized in that a compound of the formula (II) or a salt thereof,n n nis reacted to a compound of the formula (III) or a salt thereof,n n nand an aluminium(III) source, optionally, in the presence of a protic additive or solvent selected from the group consisting of alcohols or amines.n n The compounds (I) are suitable to be used for the preparation of heterocyclic compounds corresponding to (I) where the group Al(X)(Y) is replaced with an optionally substituted carbon atom, or s-triazine derivatives thereof.

    专利号:US-11472779-B1
    优先权日:2022-05-13
    标 题 :One-pot synthesis of hydrogen-bonded organic frameworks
    发明人:KHAN MOHD YUSUF; KHAN ABUZAR; HELAL AASIF; YAMANI ZAIN H
    权利人:UNIV KING FAHD PET & MINERALS
    摘要:A hydrogen-bonded organic framework (HOF) and a method of making the HOF. The HOF has at least one amine substituted organic linker and at least one carboxylic acid-based organic linker. The HOF is prepared by dissolving the linkers separately in water and mixing the aqueous solutions, without using any organic solvents, additional catalysts, or any other reagents.

    专利号:US-5087691-A
    优先权日:1989-09-01
    标题 :Poly-phenylated diamines and their use as polycondensation monomers in the synthesis of polyamide, poly(amide-imide), and polyimide polymers
    发明人:HARRIS FRANK W
    权利人:UNIV AKRON
    摘要:New polyphenylated polynuclear aromatic diamines, such as 1,3-bis[4-aminophenyl]-2,3,5-triphenylbenzene, a process for their manufacture and their use as polycondensation components for the manufacture of polyamide, polyamide-imide and polyimide polymers are described. The polymers obtained with the aromatic diamines according to the invention are readily soluble, rigid-rod polymers and are distinguished by outstanding modulus, tensile compression strength, energy absorption, coefficient of expansion and electrical properties.

    专利号:US-9951098-B2
    优先权日:2011-03-31
    标题 :Synthesis of 5-azacytidine
    发明人:RAJENDIRAN CHINNAPILLAI; NAGARAJAN PERIYANDI; VENKATESWARLAU JASTI
    权利人:RAJENDIRAN CHINNAPILLAI; NAGARAJAN PERIYANDI; VENKATESWARLAU JASTI; PHARMION LLC
    摘要:Provided herein are processes for the preparation of 5-azacytidine, useful for treating, preventing, and/or managing diseases or conditions including cancer, disorders related to abnormal cell proliferation, hematologic disorders, and myelodysplastic syndromes (MDS), wherein 5-azacytidine is represented by the structure:

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:B. Roth and J.Z. Strelitz. J. Org. Chem. 34, 821 (1969).
    参考文献:10.1515/znc-2001-7-814
    摘要:Grossmann K, Tresch S, Plath P. Triaziflam and Diaminotriazine derivatives affect enantioselectively multiple herbicide target sites. Z Naturforsch C J Biosci. 2001 Jul;56(7-8):559–69. doi: 10.1515/znc-2001-7-814.
    参考文献:10.1021/ic2003047
    摘要:Duong A, Maris T, Wuest JD. Using pyridinyl-substituted diaminotriazines to bind Pd(II) and create metallotectons for engineering hydrogen-bonded crystals. Inorg Chem. 2011 Jun 20;50(12):5605–18. doi: 10.1021/ic2003047.
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