CAS: 491-54-3; 3,5,7-Trihydroxy-2-(4-Methoxyphenyl)-4H-Chromen-4-One

该化合物是一种花草,是一种多酚化合物,常见于各种植物,特别是某些物种的叶叶和花,其特点是黄色,以其抗氧化特性而著称,有助于其潜在的健康利益; Kaempferide的分子式是C16H12O6, 其结构包括一种纤维骨,其中含有增加其再活性和生物活动的氢氧基基体; Kaempferide 表现出了抗炎,抗微生物和抗癌症特性,使其成为药理研究的话题;它经常因其在传统医学中的作用及其在饮食补充中的潜在应用而受到研究;此外,可从各种自然来源提取,包括水果,蔬菜和草药,从而帮助其进入功能性食物中;其溶解性各不相同,通常比水中有机溶剂更易溶,从而影响生物系统的生物利用率和功效.

结构式图片

上下游产品

CAS号3570-69-2 3,5,7-trihydrox... | CAS号689260-84-2 (3-(4-methoxyph... | CAS号36804-11-2 1-[2,4,6-tris(m... | CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号65982-77-6 BENZOYLOXYPHLOR... | CAS号794-94-5 4-甲氧基羟苯甲酸酐 | CAS号520-18-3 山奈酚 | CAS号20869-95-8 堪非醇3,4'-二-O-甲醚 | CAS号108-73-6 间苯三酚 | CAS号100-09-4 对甲氧基苯甲酸 | CAS号144-62-7 草酸 | CAS号64-18-6 甲酸 | CAS号108-73-6 间苯三酚 | CAS号38681-32-2 [3,5-diacetylox...

合成工艺路线路线简述

    📜山奈酚置于吡啶,Palladium 10% On Activated Carbon,氢气,Potassium Carbonate,Potassium Iodide体系中,用 甲醇,乙酸乙酯,丙酮 作为反应溶剂,化学反应 55.0H,反应生成 山奈素
    参考文献:Selective Methylation Of Kaempferol Via Benzylation And Deacetylation Of Kaempferol Acetates
    标题:Selective Methylation Of Kaempferol Via Benzylation And Deacetylation Of Kaempferol Acetates
    摘要:开发了一种选择性对卡培菲醇进行单甲基化,二甲基化和三甲基化的策略,主要基于对卡培菲醇醋酸酯的选择性苄基化和可控的去乙酰化.通过对卡培菲醇四乙酰酸酯(1)的选择性去乙酰化和苄基化,分别得到了3,4',5-三乙酰卡培菲醇(2)和7-苄基-3,4'5-三乙酰卡培菲醇(8).通过可控的去乙酰化,然后对这两种中间体进行选择性或直接的甲基化,从卡培菲醇中总产率为51-77%制备了八种甲基化卡培菲醇.
    DOI:10.3762/bjoc.11.33

    海关参考信息

    专利信息


    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:US-12036300-B2
    优先权日:2021-03-31
    标题:Methods and compositions for improving skin
    发明人:LIAO I-CHIEN; BRIEVA PATRICIA; JUCHAUX FRANCK; BOUEZ CHARBEL; ZHENG QIAN; QIAN KUN
    权利人:OREAL
    摘要:A method for managing skin tone comprising reducing the synthesis of melanin by applying a skin treatment composition to skin. The skin treatment composition may include about 0.1 to about 25 wt. % of acetyl trifluoromethylphenyl valylglycine; about 0.5 to about 30 wt. % of a polyol; about 0.1 to about 30 wt. % of a silicone, fatty compound, or a mixtures thereof, wherein the skin treatment composition is an emulsion, and all weight percentages are based on the total weight of the skin treatment composition.

    专利号:CN-101205223-B
    优先权日:2006-12-18
    标题:A kind of total synthesis method of natural product icariin compound

    专利号:CN-115612114-A
    优先权日:2021-07-14
    标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis

    专利号:CN-101205223-A
    优先权日:2006-12-18
    标 题 :A kind of total synthesis method of natural product icariin compound

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Nguyen VS, Shi L, Luan FQ, Wang QA. Synthesis of kaempferide Mannich base derivatives and their antiproliferative activity on three human cancer cell lines. Acta Biochim Pol. 2015;62(3):547-52. doi: 10.18388/abp.2015_992. Epub 2015 Sep 8. Chinese. doi: 10.3892/mmr.2011.714. Epub 2011 Dec 15. doi: 10.1002/ptr.3105. doi: 10.1002/rcm.4368. Acta Trop. 2006 Jan;97(1):102-7. Epub 2005 Oct 26.

    合成参考文献


    参考文献:10.1021/np50001a002
    摘要:Edwards JM, Raffauf RF, Le Quesne PW. Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones. J Nat Prod. 1979 Jan;42(1):85–91. doi: 10.1021/np50001a002.
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