CAS: 25178-38-5; 2-Amino-2-(2-Hydroxyphenyl)Acetic Acid

该化合物是一种氨基酸衍生物,其特点是有氨基氨基基酸组和苯环上的氢氧基基锡基组,该化合物的特点是一个箱式酸功能组,它具有酸性,通常是一种白色的,白白的晶状固体,由于其功能组的极性,在水中溶解;该氢氧体组的存在增强了其反应性和氢联结潜力,使它成为各种生物化学应用的有趣候选物;该化合物在代谢途径中可以发挥作用,并可以参与...

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上下游产品

salicylaldehyde phenylglycin methyl 2-(2-hydroxyphenyl)glycinate 2-((tert-butoxycarbonyl)amino)-2-(2-hydroxyphenyl)acetic acid Ethoxycarbonylamino-(2-hydroxy-phenyl)-acetic acid salicylaldehyde rac-Ala-OH

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于barium Dihydroxide体系中,化学反应生成2-羟基苯甘氨酸
    参考文献:The Transamination Reaction. The Effect Of Various Nuclear Substituted Phenylaminoacetic Acids On The Course Of The Reaction1
    标题:The Transamination Reaction. The Effect Of Various Nuclear Substituted Phenylaminoacetic Acids On The Course Of The Reaction1
    摘要:
    Doi:10.1021/jo01183A004

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    专利信息


    专利号:WO-9719907-A1
    优先权日:1995-11-27
    标题 :Chiral derivatives of hydroxyphenylglycin, and their use in the synthesis of pharmaceutical active principles

    专利号:US-3993666-A
    优先权日:1971-12-17
    标 题 :Coumaranedione-3-monoximes
    发明人：OEDIGER HERMANN; BRADEN RUDOLF
    权利人:BAYER AG
    摘要:Coumaranedione-3-monoximes which may be substituted in the benzene ring by halo or alkyl. The compounds are obtained by treating the corresponding 2-hydroxyphenylacetic acid lactone with nitrous acid or with an ester, salt or chloride of nitrous acid in an acid medium. The coumaranedione-3-monoxime thus obtained is an intermediate which undergoes hydrogenation in the presence of a suitable acid anhydride to afford the corresponding 3-amidocoumaranone, which compound, upon hydrolysis in the presence of dilute acid, affords the corresponding α-amino-2-hydroxyphenylacetic acid. That product is also an intermediate which has utility in the synthesis of antibiotics, including cephalosporin and penicillin derivatives.

    专利号:EP-0818438-A1
    优先权日:1995-11-27
    标 题:Chiral derivatives of hydroxyphenylglycin, and their use in the synthesis of pharmaceutical active principles

    专利号:CN-1176635-A
    优先权日:1995-11-27
    标 题:Chiral derivatives of hydroxyphenylglycin, and their use in the synthesis of pharmaceutical active principles

    专利号:CN-115612114-A
    优先权日:2021-07-14
    标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis

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    主要参考文献

    参考标题:Synthesis Of Unprotected 2-Arylglycines By Transamination Of Arylglyoxylic Acids With 2-(2-Chlorophenyl)Glycine
    作者:Haruki Inada,Masatoshi Shibuya,Yoshihiko Yamamoto |发布日期:2020.9.4
    摘要:The Transamination Of α-Keto Acids With 2-Phenylglycine Is An Effective Methodology For Directly Synthesizing Unprotected α-Amino Acids. However, The Synthesis Of 2-Arylglycines By Transamination Is Problematic Because The Corresponding Products, 2-Arylglycines, Transaminate The Starting Arylglyoxylic Acids. Herein, We Demonstrate The Use Of Commercially Available L-2-(2-Chlorophenyl)Glycine As The

    合成参考文献


    参考文献:10.1186/1471-2105-11-s1-s14
    摘要:Joshi T, Yan Z, Libault M, Jeong DH, Park S, Green PJ, Sherrier DJ, Farmer A, May G, Meyers BC, Xu D, Stacey G. Prediction of novel miRNAs and associated target genes in Glycine max. BMC Bioinformatics. 2010 Jan 18;11 Suppl 1():S14.
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