CAS: 2445-83-2; 7-Methyl-2H-Chromen-2-One

该化合物是科马林家族的有机化合物,其特点是芳香结构,一个引信苯和-环.它一般是淡黄色晶状固体,具有甜美的花粉味,经常用于香味工业和调味剂.该化合物溶于乙醇和乙醚等有机溶剂,但水溶性有限.7-甲基丙丙烯的显微光谱,使其在各种应用中有用,包括作为生物化学研究的荧光探测器.它也因其潜在的生物活动而著称,包括抗微生物和抗氧化特性.然而,安全考虑很重要,因为某些科马林衍生物在某些场合可能是有毒或致癌的.该化合物的分子配方是C10H10O2,并且具有反映其结构的分子重量.

结构式图片

欧盟法规

ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

上下游产品

CAS号698-27-1 2-羟基-4-甲基苯甲醛 | CAS号927-80-0 乙氧基乙炔,己烷溶液 | CAS号617-48-1 DL-苹果酸 | CAS号108-39-4 间甲酚 | CAS号292638-85-8 丙烯酸甲酯 | CAS号141-32-2 丙烯酸丁酯(BA) | CAS号591-24-2 3-甲基环己酮 | CAS号115560-73-1 3-hydroxy-3-(2-... | CAS号57234-27-2 1-(甲氧基甲氧基)-3-甲基苯 | CAS号108-24-7 乙酸酐 | CAS号50-85-1 4-甲基水杨酸 | CAS号50779-65-2 6-甲基苯并呋喃-2-羧酸 | CAS号20921-01-1 7-methylchroman... | CAS号17397-70-5 Coumarin-7-carb... | CAS号53666-75-4 7-methyl-6-nitr... | CAS号848352-37-4 7-methyl-3,6-di... | CAS号53878-12-9 7-(bromomethyl)...

合成工艺路线路线简述

    2-羟基-4-甲基苯甲醛置于吡啶,三乙胺体系中,用 氯仿 用作溶剂,化学反应 5.0H,反应生成7-甲基香豆素
    参考文献:Desai,Vidya G.; Shet,Jyoti B.; Tilve,Santosh G.,Journal Of Chemical Research-Part S,2003,# 10,P. 628-629
    标题:Desai,Vidya G.; Shet,Jyoti B.; Tilve,Santosh G.,Journal Of Chemical Research-Part S,2003,# 10,P. 628-629

    海关参考信息

    专利信息


    专利号:US-7598291-B2
    优先权日:2004-09-02
    标题 :Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid, a lipoic acid analogue or derivative, a bioflavonoid, a constituent of ginkgo, or an isoflavone. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

    专利号:US-2010160244-A1
    优先权日:2004-09-02
    标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

    专利号:US-2022048879-A1
    优先权日:2020-08-13
    标 题:Synthesis of small molecules inspired by Phomoxanthone A
    发明人:ALI RAMEEZ; MATTSON ANITA
    权利人:WORCESTER POLYTECH INST
    摘要:Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.

    专利号:US-2006251786-A1
    优先权日:2005-04-19
    标 题:Cyclopropanated coumarin derivatives
    发明人:TURIN LUCA
    权利人:TURIN LUCA
    摘要:This invention provides compound or a mixture of compounds of formula (I): n n nwherein R and R 1 are independently a substituted or unsubstituted, straight or branched alkyl or alkoxy group having up to 5 carbons, phenyl or substituted phenyl; R 2 and R 3 are each independently H or CH 3 ; m is an integer from 0 to 4, and n is an integer from 0 to 2. A method for the synthesis of these compounds is also provided, as is their use as aromachemicals and flavorants and compositions, products and articles containing them.

    专利号:WO-2022036040-A1
    优先权日:2020-08-13
    标 题 :Synthesis of small molecules inspired by phomoxanthone a

    专利号:JP-H06500556-A
    优先权日:1990-08-28
    标题 :Solid-support synthesis of 3'-tailed oligonucleotides via linking molecules
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    合成参考文献


    摘要:Mondal, M.; Bora, U., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 2, 505.
    摘要:Ruan, Z.; Huang, Z.; Kuciński, K.; Ackermann, L., Science of Synthesis: Special Topics, (2021) 1, 246.
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