CAS: 164470-64-8; Fmoc-4-Amb-Oh

相似化合物

33233-67-9 56-91-7 210963-04-5

上下游产品

CAS号56-91-7 氨甲苯酸 | CAS号71989-31-6 Fm°C-L-脯氨酸 | CAS号82911-69-1 9-芴甲基-N-琥珀酰亚胺碳酸酯 | CAS号28920-43-6 芴甲氧羰酰氯(Fm°C-Cl) | CAS号41651-87-0 4-[(hydrazinylm...

📜4-氨甲基苯甲酸,Fluorenylmethoxy Chloroformate 以 1,4-二氧六环,水,Sodium Carbonate 用作溶剂,化学反应生成Fmoc-(4-氨甲基)苯甲酸
参考文献:Para-Aminomethylaryl Carboxamide Derivatives
标题:Para-Aminomethylaryl Carboxamide Derivatives
摘要:Formula I的对氨基甲基芳基羧酰胺是vla-4和/或α4β7的拮抗剂,因此可用于抑制或预防细胞粘附和细胞粘附介导的病理.这些化合物可以制成药物组合物,并适用于治疗哮喘,过敏,炎症,多发性硬化以及其他炎症性和自身免疫性疾病.

专利信息

专利号:US-2025090698-A1
优先权日:2018-11-27
标题 :Small molecule inhibitors for early diagnosis of prostate specific membrane antigen cancers and neurodegenerative diseases
发明人：CHELVAM VENKATESH; SENGUPTA SAGNIK; KRISHNAN MENA ASHA; PANDIT AMIT
权利人:INDIAN INSTITUTE OF TECH INDORE
摘要:Accordingly, embodiments herein disclose a conjugate D-E-F having binding affinity≤60 nM; wherein D comprises AAPT ligand or derivative thereof, E comprises a spacer comprising AA1, AA2, AA3 and/or AA4 and F is a chelating group. The conjugate also comprising AAPT ligand conjugated arene chelating linker for delivery of 99mTc radioisotope. Another embodiment also discloses a AAPT-PCa DOTA bioconjugate. An embodiment also discloses method of solid phase synthesis of AAPT-ligand. It also discloses a method of solid phase synthesis of AAPT-PCa DOTA bioconjugate for delivering of radioisotopes.

专利号:WO-2013057186-A1
优先权日:2011-10-19
标题 :Photolabile linker for the synthesis of hydroxamic acids
发明人：NIELSEN THOMAS E; QVORTRUP KATRINE
权利人:UNIV DANMARKS TEKNISKE
摘要:The present invention relates to a photolabile hydroxamate linker based on the o - nitroveratryl group and its application for multistep solid-phase synthesis and controlled photolytic release of hydroxamic acids. The invention provides a method for producing a solid support comprising a hydroxylamine - functionalized photolabile linker, and the so produced hydroxylamine - functionalized photolabile solid support. The invention further provides a method for synthesizing a one-bead-one compound library of hydroxamic acid derivatives on a photolabile linker, as well as a method for screening a library of hydroxamic acid derivatives.

专利号:WO-2025088147-A1
优先权日:2023-10-27
标题 :Theranostic psma-targeting ligands for the diagnosis and treatment of psma-expressing cancers and their solid phase synthesis
发明人：Schäfer Martin; BAUDER-WUEST ULRIKE; ROSCHER MAREIKE; REMDE YVONNE; BENEÅ OVÃ?-SCHÄFER MARTINA; BARINKA CYRIL; KUTILOVÃ? ZSÓFIA; MOTLOVÃ? LUCIA
权利人:DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS
摘要:The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and radiopharmaceuticals for the treatment of various disease states of PSMA-expressing cancers, especially prostate cancer, and metastases thereof. Further the present invention provides synthetic procedures for the synthesis of such PSMA-targeting ligands.

专利号:US-8410028-B2
优先权日:2003-12-17
标 题:Methods for synthesis of encoded libraries
发明人：MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A
权利人:MORGAN BARRY; HALE STEPHEN; ARICO-MUENDEL CHRISTOPHER C; CLARK MATTHEW; WAGNER RICHARD; ISRAEL DAVID I; GEFTER MALCOLM L; BENJAMIN DENNIS; HANSEN NILS JAKOB VEST; KAVARANA MALCOLM J; CREASER STEFFAN PHILLIP; FRANKLIN GEORGE J; CENTRELLA PAOLO A; ACHARYA RAKSHA A; GLAXOSMITHKLINE LLC
摘要:The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

专利号:WO-02083606-A1
优先权日:2001-04-17
标 题:A linker system for the synthesis and screening of combinatorial libraries of polyamine derivatives on water compatible supports
发明人：HALL DENNIS G; WANG FAN
权利人:UNIV ALBERTA; HALL DENNIS G; WANG FAN
摘要:The invention is directed to resin-conjugated polyamine combinatorial libraries and methods for making and using them, e.g., methods for screening for polyamine binding molecules in biological samples. The invention provides protected benzophenone-substituted resins, and methods for their synthesis. The invention provides hydroxy-triarylmethane-conjugated resins, and methods for their synthesis. The invention provides chlorotriarylmethane resins, and methods for their synthesis. The invention provides resin-conjugated peptide libraries, and methods for their synthesis.

专利号:US-7365178-B2
优先权日:2003-04-01
标 题:Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis
发明人：CAMPBELL DAVID ALAN; LIYANAGE MAREK; SZARDENINGS ANNA KATRIN; WU MIN
权利人:ACTIVX BIOSCIENCES INC
摘要:The present invention provides tagged acyl phosphate probes (“TAPPsâ€?), and methods of their preparation and use. The subject methods and compositions can provide enhanced simplicity and accuracy in identifying changes in the presence, amount, or activity of target proteins in a complex protein mixture, preferably nucleotide binding proteins using nucleotide binding protein-directed TAPPs. The profiling methods described herein can have a number of steps leading to the identification of target nucleotide binding protein(s) in a complex protein mixture.