专利号:US-10745675-B2 优先权日:2017-05-02 标题:Modified enzymes for producing increased isomelezitose 发明人:COTE GREGORY L; SKORY CHRISTOPHER D 权利人:THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 摘要:Provided herein are compositions and methods for the synthesis of the trisaccharide, isomelezitose, using genetically modified glucansucrase enzymes from representative microorganisms, including lactic acid bacteria such as Leuconostoc mesenteroides . Various modified enzymes are detailed, increasing isomelezitose yields and provide the foundation for large-scale production of isomelezitose for food, industrial and biomedical applications.
专利号:US-2025207276-A1 优先权日:2023-12-21 标 题 :Methods of preparing a catalyst and an electrolytic cell for use in synthesising ammonia, and methods of synthesising ammonia 发明人:HO JOHNNY CHUNG YIN; YIN DI; CHEN DONG; QUAN QUAN 权利人:UNIV CITY HONG KONG 摘要:One aspect of the present invention is concerned with a method of preparing a catalyst for use in synthesizing ammonia from nitrate. The method has the steps of i) providing a nickel foam material, ii) removing an oxide layer on the nickel foam material, iii) subjecting the nickel foam material to cooper sulphate (Cu2SO4) solution for a predetermined period of time for forming a copper (Cu) dopped nickel foam electrode, and iv) subjecting the Cu dopped nickel foam electrode to an annealing treatment at a predetermined temperature for a predetermined period of annealing time in atmospheric air thus forming a catalyst of copper oxide-nickel oxide nickel foam (CuO/NiO@NF) with a heterostructure. Other aspects of the invention are concerned with a method of preparing an electrolytic cell for use in synthesizing of ammonia, and a method of synthesis of ammonia from nitrate.
专利号:US-6153615-A 优先权日:1991-12-26 标 题 :Blocking induction of tetrahydrobioterin to block induction of nitric oxide synthesis 发明人:GROSS STEVEN S 权利人:CORNELL RES FOUNDATION INC 摘要:Guanosine triphosphate pathway tetrahydrobiopterin synthesis antagonist and/or pterin salvage pathway tetrahydrobiopterin synthesis antagonists are administered to inhibit nitric oxide synthesis from arginine in vascular cells in a subject in need of such inhibition (e.g., for prophylactic or curative effect for endotoxin- or cytokine-induced hypotension or for restoration of vascular contractile sensitivity to pressor agents in the treatment of such hypotension). The tetrahydrobiopterin synthesis antagonist may be administered with α 1 -adrenergic agonist or with nitric oxide synthase inhibitor. The tetrahydrobiopterin synthesis antagonists are also administered to attenuate inflammation caused by induced nitric oxide production in immune cells. Unwanted counterproductive or side effects can be eliminated or ameliorated by administration additionally of levodopa with or without carbidopa and L-5-hydroxytryptophane.
专利号:US-6274581-B1 优先权日:1991-12-26 标 题 :Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis 发明人:GROSS STEVEN S 权利人:CORNELL RES FOUNDATION INC 摘要:Guanosine triphosphate pathway tetrahydrobiopterin synthesis antagonist and/or pterin salvage pathway tetrahydrobiopterin synthesis antagonist are administered to inhibit nitric oxide synthesis from arginine in vascular smooth muscle cells in a subject in need of such inhibition (e.g. for prophylactic or curative effect for cytokine-induced hypotension or for restoration of vascular contractile sensitivity to pressor agents in the treatment of such hypotension).
专利号:US-2024318335-A1 优先权日:2023-03-22 标 题:Catalyst, its preparation and its use in ammonia synthesis 发明人:HO JOHNNY CHUNG YIN; CHEN DONG; ZHANG SHAOCE 权利人:UNIV CITY HONG KONG 摘要:A catalyst in ammonia synthesis includes a first layer of metal monochalcogenide-based material; a second layer of metal monochalcogenide-based material stacked with and is spaced from the first layer of metal monochalcogenide-based material by a first distance; wherein the metal monochalcogenide-based material includes SnS. A method of preparing the catalyst and an electrochemical ammonia synthesizing device making use of the catalyst thereof are also addressed.
专利号:US-9162993-B2 优先权日:2012-04-18 标 题:Preparation and pharmaceuticals of biphenyl benzamide-derived derivatives 发明人:CHANG DEH-MING; HUANG HSU-SHAN; LEE CHIA-CHUNG; CHEN CHUN-LIANG 权利人:NAT DEFENSE MEDICAL CT 摘要:The present invention provides a biphenyl benzamide-derived derivatives, which structure is selected from formula I or formula II n nand the synthesis and the application thereof.
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