欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
lysidine propyl bromide propylamine 2-bromoethylamine hydrobromideN,N'-Di(p-methoxybenzoyl)-N-n-propylethylendiamin N,N'-Di(p-nitrobenzoyl)-N-n-propylethylendiamin tert-butyl N-[2-(propylamino)ethyl]carbamate 1,4,7,10-Tetrapropyl-°Ctahydro-1,3a,4,6a,7,9a,10,12a-°Ctaaza-3b,6b,9b,12b-tetraphospha-tetracyclopenta[a,c,e,g]cyclo°Ctene 合成工艺路线路线简述
- 合成目标产物 N-(N-Propyl)Ethylenediamine 主要起始原料 1-Propanol And Ethylenediamine
- (文献来源)合成步骤主要原料 1-Propanol 和 Ethylenediamine
📜Diisopropyl (2-(Propylamino)Ethyl)Phosphoramidate置于盐酸体系中,化学反应生成N-丙基亚乙基二胺
参考文献:Phosphoramides ω Aminès
标题:Phosphoramides ω Aminès
摘要:
Doi:10.1016/s0022-328X(00)85441-8
专利信息
专利号:US-9738647-B2
优先权日:2009-12-24
标题:Methods for the synthesis of polycyclic guanidine compounds
发明人:GRIDNEV ALEXEI
权利人:NOVOMER INC; SAUDI ARAMCO TECH CO
摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.
专利号:US-5369017-A
优先权日:1994-02-04
标题 :Process for solid phase glycopeptide synthesis
发明人:WONG CHI-HUEY; SCHUSTER MATTHIAS
权利人:SCRIPPS RESEARCH INST
摘要:A process for the synthesis of a glycopeptide using a solid phase matrix is disclosed. The matrix is compatible with aqueous and organic solvents and is comprised of a silica-based solid support to which is linked a two-part spacer group having a chain length of about 12 to about 40 methylene groups. The first part of the spacer is covalently bonded to the silica-based support and has a length of about 3 to about 10 methylene groups. The second spacer part is covalently bonded to the first part of the spacer and comprises the distal end of the two part spacer. The second part is soluble as a free molecule in each of water, dimethylformamide and dichloromethane and has a terminal amine or hydroxyl group to which the C-terminal residue of the peptide portion of the glycopeptide chain is bonded. The chain of atoms connecting the desired glycopeptide to the solid phase matrix also includes a moiety having a selectively severable bond which on cleavage of that bond separates the matrix from whatever else is bonded to that moiety.
专利号:US-6143849-A
优先权日:1996-11-27
标题:Synthesis of acrylate and alkyl acrylate monomers and polymers of chelators
发明人:PURANIK DHANANJAY B; CHANG EDDIE L
权利人:US NAVY
摘要:Multifunctional chelating groups are covalently bound to acrylate or methylate monomers. These monomers are polymerized. The resulting polymers are highly substituted with chelating groups and are useful for removing metals from fluids such as liquid hydrocarbons. An example of a polymer according to this invention has the following structure: ##STR1## wherein Q is a saturated or unsaturated aliphatic group having 1 to about 200 carbon atoms and is typically an unsubstituted unbranched alkylene, a substituted unbranched alkylene, a substituted branched alkylene, or an unsubstituted branched alkylene, and is an integer having a value of at least 1.
专利号:US-6689919-B1
优先权日:1999-09-22
标 题 :Catalysts for oxidative polymerization of fluorophenol, method of oxidative polymerization of fluorophenol, and poly(oxyfluorophenylene) derivative
发明人:TSUCHIDA EISHUN; OYAIZU KENICHI; KUMAKI YOSUKE; SAITO KEI
权利人:JAPAN SCIENCE & TECH CORP
摘要:The synthesis of fluoropolyarylene ether with a high degree of polymerization is enabled, by using a copper complex catalyst with an oxidation potential in the range of -1V to 2V, for the oxidative polymerization of fluorophenols that contain at least one hydrogen atom as well as a fluorine atom bonded to the carbon atoms constituting the benzene ring.
专利号:US-2013102730-A1
优先权日:2010-04-02
标 题:Polyamine-containing polymers and methods of synthesis and use
发明人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN
权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES
摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).
专利号:US-2024279231-A1
优先权日:2021-05-20
标题:Map4k4 inhibitors and methods of synthesis and use thereof
发明人:AWASTHI VIBHUDUTTA; EEDA VENKATESWARARAO
权利人:UNIV OKLAHOMA
摘要:The compound DMX-5804, IUPAC name 5-(4-(2-methoxyethoxy)phenyl)-7-phenyl-3,4a,7,7a-tetrahydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, is a potent and selective inhibitor of mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4). The present disclosure describes a scalable and practical synthesis process for making DMX-5804. The process (1) doesn't rely on transition metals, (2) has reduced duration of reactions, (3) is streamlined with significantly improved yields using low cost raw materials, (4) includes no microwave-assisted reactions, (5) does not require column purification, and (6) generally results in crystalized products having over a 95% purity in each step. The present disclosure also describes DMX-5804 analogs and derivatives for use in inhibiting MAP4K4, and scalable and practical processes for making such DMX-5804 analogs.