CAS: 105-40-8; Ethyl Methylcarbamate

相似化合物

16066-84-5 51779-32-9 39896-97-4

上下游产品

acetamide sodium ethanolate chloroformic acid ethyl ester methylamineN-methyl-acetamideN-methyl-acetamide ethyl bromide N-methylsulfamic acid ethyl N-methyl-N-nitros°Carbamate

📜乙胺 反应生成氨基甲酸乙酯
参考文献:Process For The Preparation Of Alkyl Carbamates
标题:Process For The Preparation Of Alkyl Carbamates
摘要:该发明涉及一种高效的方法,通过在催化剂系统的存在下,将甲基胺或n,N'-二甲基脲与一氧化碳,氧化剂和一种单醇反应,制备甲基甲基碳酸酯.该催化剂系统包括(i)从铂族金属和可溶性铂族金属化合物组成的群体中选择的前驱体,以及(II)包括至少一种含卤素化合物的促进剂,所述含卤素化合物选自碱金属卤化物,碱土金属卤化物,季铵盐卤化物,含卤原子的氧化酸及其盐,含有卤素离子,有机卤化物和卤素分子的复合物.

专利信息

专利号:US-9963422-B2
优先权日:2013-03-11
标题:Process for the synthesis of melphalan and the hydrochloride salt
发明人：PULLAGURLA MANIK REDDY; RANGISETTY JAGADEESH BABU; NANDAKUMAR MECHERIL VALSAN; VEDURURI MADHAVA REDDY; SAMIREDDI SREENU
权利人:BIOPHORE INDIA PHARMACEUTICALS PVT LTD
摘要:The present invention relates to an improved process for the preparation of Melphalan, more specifically the invention relates to an efficient process for the preparation of substantially pure Melphalan hydrochloride (I).

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:WO-9710221-A1
优先权日:1995-09-15
标 题:Synthesis of quinazolinone libraries
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TORREY PINES INST
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-6664282-B2
优先权日:1999-09-17
标 题:Synthesis of [3,5,7]-1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds
发明人：ELABDELLAOUI HASSAN M; OSTRESH JOHN M; HOUGHTEN RICHARD A
权利人:TORREY PINES INST
摘要:Individual substituted [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-one compounds and their pharmaceutically-acceptable salts are disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.

专利号:US-7476757-B2
优先权日:2005-02-22
标 题:Process for the synthesis of enantiomeric indanylamine derivatives
发明人：BOULTON LEE TERENCE; LENNON IAN CAMPBELL; BAHAR ELIEZER
权利人:TEVA PHARMA
摘要:A process for manufacturing (R)-propynylaminoindans, and alternatively, a process for manufacturing (S)-propynylaminoindans. The chiral propynylaminoindans include alkoxy or alkylcarbamates derivatives. The process comprises transfer or pressure hydrogenation in the presenc of an optically active catalyst to reduce 1-indanones. The chiral product, either (S)- or (R)-indanols undergo nucleophilic substitution to produce the named product. In an additional aspect, the invention relates to novel intermediates and compounds, namely, substituted indanones, substituted (S)-indanols and substituted (R)-indanols.