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CAS号6671-49-4 Benzenesulfonic... | CAS号88-73-3 邻氯硝基苯 | CAS号17691-19-9 4-氯-3-硝基苯磺酸钠 | CAS号635-22-3 4-氯-3-硝基苯胺 | CAS号98-60-2 对氯苯磺酰氯 | CAS号121-18-6 4-氯-3-硝基苯磺酸 | CAS号98-66-8 4-氯苯磺酸 | CAS号7790-94-5 氯磺酸 | CAS号119-00-6 2-nitrobenzene-... | CAS号10026-13-8 五氯化磷 | CAS号22025-44-1 4-[(4-乙氧基苯基)氨基]... | CAS号2360-19-2 4-氨基-3-硝基苯磺酰胺 | CAS号126813-43-2 N-(2-aminoethyl... | CAS号97-09-6 3-硝基-4-氯苯磺酰胺 | CAS号121-18-6 4-氯-3-硝基苯磺酸 | CAS号349-04-2 4-chloro-3-nitr... | CAS号35964-48-8 1-chloro-4-[(4-... | CAS号137-49-5 4-氯-3-硝基-N-苯基苯磺酰胺 | CAS号12223-84-6 3-硝基-4-(苯氨基)苯磺酰胺 | CAS号2489-48-7 3-(4-Hydroxyben...合成工艺路线路线简述
- 合成目标产物 4-Chloro-3-Nitrobenzenesulfonyl Chloride 主要起始原料 4-Chlorobenzenesulfonyl Chloride
- (文献来源)合成步骤主要原料 4-Chlorobenzenesulfonyl Chloride
硝基氯苯置于氯磺酸体系中,化学反应生成 4-氯-3-硝基苯磺酰氯
参考文献:Anti-Inflammatory 1-[3-(Dialkylamino)Propyl]-2-Acylaminobenzimidazoles
标题:Anti-Inflammatory 1-[3-(Dialkylamino)Propyl]-2-Acylaminobenzimidazoles
摘要:1-[3-(二烷基氨基)丙基]-2-酰胺基苯并咪唑和2-酰胺基氨基-3-[3-(二烷基氨基)丙基]咪唑并[4,5-B]吡啶以及它们与药用可接受的酸盐,是一类新型化合物,在治疗炎症性疾病中有用.提供了替代制备方法,并详细描述了主要的合成途径.
专利信息
专利号:US-4552984-A
优先权日:1982-01-21
标题 :Process for preparation of α,α-difluoroalkoxy or α,.alpha.
发明人:DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of alpha , alpha -difluoroalkoxy or alpha , alpha -difluoroalkylthiophenyl sulfones, in which a polyhaloalkoxybenzene or a polyhaloalkylthiobenzene is reacted with a sulfonic acid, a derivative or a precursor of this acid, in the presence of boron trifluoride in an amount such that the absolute pressure of the boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent. The resultant products are useful as intermediates in the synthesis of compounds having a phytosanitary (e.g., herbicidal) or pharmaceutical activity.
专利号:US-10759747-B2
优先权日:2016-04-29
标 题 :Alkylation method
发明人:KHAN IMTIAZ; MCROBBIE GRAEME; KIRJAVAINEN ANNA
权利人:GE HEALTHCARE LTD; KING S COLLEGE LONDON
摘要:The present invention relates to a method of radiochemical synthesis. Novel methods useful in the synthesis of a positron emission tomography (PET) tracer, and novel intermediates useful in said method are provided that have advantages over known methods.
专利号:US-8633337-B2
优先权日:2010-05-14
标 题 :Method and synthesis
发明人:BRATHE ANDERS; OLSSON ANDREAS; THANING MIKKEL; BUGGE STEFFEN
权利人:BRATHE ANDERS; OLSSON ANDREAS; THANING MIKKEL; BUGGE STEFFEN; GE HEALTHCARE LTD
摘要:The present invention provides a method for the preparation of a radiolabeled guanidine derivative, in particular wherein the radiolabeled guanidine derivative is a positron emission tomography (PET) tracer. Certain intermediates useful in said method are also provided, as well as means for carrying out said method in an automated fashion. The method of the invention provides advantages over known methods for the preparation of radiolabeled guanidine derivatives.
专利号:CN-117720498-A
优先权日:2023-11-03
标 题 :Synthesis of a new coumarin derivative containing a sulfonamide fragment and preparation method and application of its composition
专利号:US-5344947-A
优先权日:1986-10-01
标题 :Optically active derivatives of glycidol
发明人:SHARPLESS KARL B; KLUNDER JANICE M
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Optically active derivatives of glycidol are disclosed. These compounds, (2S) and (2R) glycidyl tosylate and (2S) and (2R) glycidyl 4-chloro-3-nitrobenzenesulfonate can be readily crystallized to high enantiomeric purity. Their use in other synthesis reactions is also described.
专利号:SU-1754712-A1
优先权日:1989-12-21
标 题 :N-(3-nitro-4-chlorophenylsulfonyl)-anthranilic acid as an intermediate for synthesis of n-(4-chlorophenyl)-2-[(3-nitro- 4-chlorophenylsulfonyl)-amino]-5-bromobenzamide, showing antitrichocephaliasis activity