CAS: 859825-79-9; 7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-2-Amine
该化合物是一种环环环有机化合物,其特点是复杂的双环结构,其中含有和环,该化合物具有苯基组和氯原子的特点,有助于其独特的化学特性;氨基组在2位置的存在增强了其生物活动的潜力,使其对药用化学感兴趣;四氢丙烯诺结构表明它是一种饱和衍生物,可能影响其溶解性和再活性;氯的次构成可影响化合物的电子特性,并可能在其与生物目标的互动中发挥作用;
- 英文名称7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-2-Amine
- 中文名称7-苄基-4-氯-5,6,7,8-四氢吡啶并[3,4-d]嘧啶-2-胺
- IUPAC名称7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amine
- 其它别名7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-2-Amine; 7-Benzyl-4-Chloro-5H,6H,7H,8H-Pyrido[3,4-D]Pyrimidin-2-Amine; 4-Chloro-7-(Phenylmethyl)-6,8-Dihydro-5H-Pyrido[3,4-D]Pyrimidin-2-Amine; Pyrido[3,4-D]Pyrimidin-2-Amine, 4-Chloro-5,6,7,8-Tetrahydro-7-(Phenylmethyl)-
- CAS编号859825-79-9
- MFCD编号:MFCD11518949
- 分子式:C14H15ClN4分子量:274.76
- 产品CID: 1859620
- 产品分类有机原料→分子砌块→芳杂环类化合物→嘧啶类化合物
物理性质
MSDS等安全信息
上下游产品
2-amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(4aH)-one ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydr°Chloride 2-amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-ol (2-amino-4-(butylamino)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl)(phenyl)methanone 4-butyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-diamine7-benzyl-N4-butyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-diamine合成工艺路线路线简述
- 合成目标产物 7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-2-Amine 主要起始原料 2-Amino-7-Benzyl-5,6,7,8-Tetrahydro-3H-Pyrido[3,4-D]Pyrimidin-4-One
- 62458-92-8 = 859825-79-9
反应条件:1.1 Reagents: N,N-Dimethylaniline,Phosphorus Oxychloride Solvents: 1,2-Dichloroethane; Overnight,Rt -> Reflux1.2 Reagents: Water; Cooled1.3 Reagents: Sodium Carbonate; Neutralized
标题:Substituted 5,6-(Dihydropyrido[3,4-D]Pyrimidin-7(8H)-Yl)-Methanones As P2X7 Antagonists
作者:Ziff,Jeannie; Et Al
参考文献:Acs Chemical Neuroscience 日期:2016 卷标:7(4) 页码:498-504]
113-00-8 + 52763-21-0 + 463-79-6 = 859825-79-9
反应条件:1.1 Solvents: Tert-Butanol; 2 H,Rt -> Reflux1.2 Reagents: Hydrochloric Acid Solvents: Water; 30 Min,Ph 5,Rt2.1 Reagents: N,N-Dimethylaniline,Phosphorus Oxychloride Solvents: 1,2-Dichloroethane; Overnight,Rt -> Reflux2.2 Reagents: Water; Cooled2.3 Reagents: Sodium Carbonate; Neutralized
标题:Substituted 5,6-(Dihydropyrido[3,4-D]Pyrimidin-7(8H)-Yl)-Methanones As P2X7 Antagonists
作者:Ziff,Jeannie; Et Al
参考文献:Acs Chemical Neuroscience 日期:2016 卷标:7(4) 页码:498-504]
113-00-8 + 52763-21-0 + 463-79-6 = 859825-79-9
反应条件:1.1 Solvents: Ethanol; 16 H,120 °C2.1 Reagents: Phosphorus Oxychloride; 16 H,100 °C
标题:Design And Synthesis Of Tetrahydropyridopyrimidine Based Toll-Like Receptor (Tlr) 7/8 Dual Agonists
作者:Mcgowan,David C.; Et Al
参考文献:Bioorganic & Medicinal Chemistry Letters 日期:2018 卷标:28(19) 页码:3216-3221
📜N-苄基-3-氧代哌啶-4-羧酸乙酯盐酸盐置于三氯氧磷体系中,用 乙醇 作为反应溶剂,化学反应 19.0H,反应生成 7-苄基-4-氯-5,6,7,8-四氢吡啶并[3,4-D]嘧啶-2-胺
参考文献: Piperidino-Pyrimidine Derivatives For The Treatment Of Viral Infections[fr] Dérivés De Pipéridino-Pyrimidine Pour Le Traitement D'Infections Virales
标题: Piperidino-Pyrimidine Derivatives For The Treatment Of Viral Infections[fr] Dérivés De Pipéridino-Pyrimidine Pour Le Traitement D'Infections Virales
摘要:该发明涉及哌啶基吡啶啉衍生物,其制备方法,药物组合物以及它们在治疗病毒感染中的用途.
海关参考信息
- 2902300000-甲苯
2921199090-其他无环单胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
