CAS: 76-78-8; Quassin

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CAS号26121-57-3 Picrasa-2,12-di... | CAS号30315-04-9 黄苦木素 B 乙酸酯

📜Neoquassin置于silver Carbonate体系中,用 苯 作为反应溶剂,化学反应 2.5H,以3.8 Mg的收率获得产物苦木素
参考文献:(+)-Quassin的全合成.
标题:(+)-Quassin的全合成.
摘要:描述了由天然存在的(S)-(+)-香芹酮的(+)-Quassin的全合成.步骤总数为28,总产率约为2.6%.构建四环碳骨架的合成策略是基于c-> Abc-> Abcd环的成环序列,其中涉及醛醇缩合反应,分子内diels-Alder反应和分子内酰化反应为关键步骤.然后环a和环c的随后官能化提供了目标(+)-Quassin.
DOI:10.1021/jo000877G

专利信息

专利号:CA-2640585-A1
优先权日:2003-02-05
标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one

专利号:US-11987546-B2
优先权日:2017-09-21
标 题 :Polycyclic carbogenic molecules and uses thereof as anti-cancer agents
发明人：THOMSON REGAN J; ROBINSON EMILY E
权利人:UNIV NORTHWESTERN
摘要:Disclosed are new polycyclic carbogenic molecules and their methods of synthesis. The new polycyclic carbogenic molecules may be utilized in anti-cancer therapies. In particular, the polycyclic carbogenic molecules may be formulated as pharmaceutical compositions that comprise the small molecules, which compositions may be administered in methods of treating and/or preventing cell proliferative diseases and disorders such as cancer. The new polycyclic carbogenic molecules may be prepared from vinyl- or allyl-substituted cyclohexenone precursors via preparation of a silyl bis-enol ether intermediate.