CAS: 60145-20-2; 2,2',3,3',5-Pentachlorobiphenyl
该化合物是多氯联苯(PCB)家族的成员,是合成有机化学品,以其环境持久性和潜在毒性而著称,该化合物由两个相连的苯环组成,五个氯原子被替换在联苯结构的特定位置上,其物理特性包括水中的高熔点和低溶解度,使其在有机溶剂中更易溶解. 2,2',3,3',3',5-五氯联苯的特点是其稳定性和耐降解性,这助长了其在环境和活生物体中的积累.由于这些关切,许多国家对多氯联苯的使用进行了严格的管制或禁止.环境监测和补救工作正在进行,以解决多氯联苯造成的污染,包括2,2',3',3',5-五溴二苯醚.
- 英文名称2,2',3,3',5-Pentachlorobiphenyl
- 中文名称2,2',3,3',5-五氯联苯
- IUPAC名称1,2,5-trichloro-3-(2,3-dichlorophenyl)benzene
- 其它别名2,2',3,3',5-Pentachlorobiphenyl; 2,2',3,3',5-Pentrachloro-1,1'-biphenyl; 2,3,2',3',5'-Pentachlorobiphenyl; 2,3,5,2',3'-Pentachlorobiphenyl; PCB 83
- CAS编号60145-20-2
- MFCD编号:MFCD00661140
- FDA UNII编号:S7VW40I05H
- 分子式:C12H5Cl5分子量:326.43
- 产品CID: 1578146
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: SUBRHHYLRGOTHL-UHFFFAOYSA-N
- InChI=1S/C12H5Cl5/c13-6-4-8(12(17)10(15)5-6)7-2-1-3-9(14)11(7)16/h1-5H
- 计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
2,3-dichloroaniline 1,2,4-Trichlorobenzene 1-bromo-2,3,5-trichlorobenzene 2,3-dichlorobenzeneboronic acid合成工艺路线路线简述
📜2,3-二氯苯胺,三氯苯置于sodium Acetate,亚硝酸体系中,化学反应生成 2,2',3,3',5-五氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Synthesis Of Chlorinated Biphenyls By Suzuki Cross-Coupling Using Diamine Or Diimine-Palladium Complexes作者:Tuula Kylmälä,Noora Kuuloja,Youjun Xu,Kari Rissanen,Robert Franzén |发布日期:2008.8
摘要:And Their Reduced Diamine Counterparts 3B,3D-3G And 3I Form Complexes 4A-4I, 5B,5D-5G, And 5I With Pdcl2 In Dmf Or Methanol. Using 1 Mol-% Of The Isolated Complexes 4E And 5F Many Polychlorinated Biphenyls (Pcbs) Can Be Prepared In Moderate To Excellent Yields According To The Suzuki Crosscoupling Protocol With Contact To Air. Several 4-Acetylbiphen
合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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