合成目标产物 Tert-Butylhydroquinone 主要起始原料 Hydroquinone And Tert-Butanol
(文献来源)合成步骤主要原料 Hydroquinone 和 Tert-Butanol
1,2,4-苯三酚置于palladium On Activated Charcoal 氢气体系中,化学反应生成特丁基对苯二酚 参考文献: Lignin Oxidation And Products Thereof[fr] Oxydation De La Lignine Et Produits Dérivés 标题: Lignin Oxidation And Products Thereof[fr] Oxydation De La Lignine Et Produits Dérivés
专利号:US-2006128930-A1 优先权日:2004-12-03 标题 :Synthesis of sterically hindered phenol based macromolecular antioxidants 发明人:DHAWAN ASHISH; CHOLLI ASHOK L 权利人:DHAWAN ASHISH; CHOLLI ASHOK L 摘要:Disclosed is a method for the synthesis of sterically hindered polymeric antioxidants based on phenol type antioxidant monomers. The method includes polymerizing and alkylating a phenol containing monomer represented by the following structural formula: n n nto produce a sterically hindered polymeric macromolecular antioxidant. X, R 10 and q are as defined herein. The disclosed method is a simple, direct and economical process for the synthesis of sterically hindered polymeric macromolecular antioxidants.
专利号:US-7678877-B2 优先权日:2004-12-03 标题 :Process for the synthesis of polyalkylphenol antioxidants 发明人:YANG SUIZHOU; CHOLLI ASHOK L 权利人:POLNOX CORP 摘要:Disclosed is a method for the synthesis of sterically hindered polymeric antioxidants based on phenol type antioxidant monomers. The method includes partially etherifying, polymerizing and thermally rearranging a phenol containing monomer represented by the following structural formula: n nto produce a sterically hindered polymeric macromolecular antioxidant. X, R 10 and q are as defined herein. The disclosed method is a simple, direct and economical process for the synthesis of sterically hindered polymeric macromolecular antioxidants.
专利号:US-12018313-B2 优先权日:2016-12-28 标题:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles 发明人:EMBREE MALLORY 权利人:NATIVE MICROBIALS INC 摘要:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.
专利号:US-7825257-B1 优先权日:2007-10-23 标题 :Synthesis of benzotriazole monomer 发明人:DEO KESHAV; SHAH CHANDRAKANT CHUNILAL; PATEL KALPESH; PATEL NILPESH; PAREKH VIRAL; PATEL RONAK; SONI JIGNESH; SHAH HIRAL; SEELYE DAVID E; NANDU MAHENDRA P 权利人:BAUSCH & LOMB 摘要:The synthesis of benzotriazole monomers and the use of the benzotriazole monomers and one or more other monomers to prepare ultraviolet (UV) light absorbing polymer compositions. The synthetic methods described in this application provide a significant improvement over the previous methods used to prepare benzotriazole monomers.
专利号:WO-9200947-A1 优先权日:1990-07-09 标题 :Improved esterification of oxyhydrocarbon polyols and ethers thereof, and products therefrom 发明人:MILSTEIN NORMAN 权利人:HENKEL CORP 摘要:Conducting esterifications of oxyhydrocarbon polyols and their ethers in the presence of a reducing agent, or pretreatment of these materials with a reducing agent allows the synthesis of light colored ester products without bleaching. This method is particularly useful in connection with preparation of fatty acid esters of sorbitan from sorbitol when cyclization of the sorbitol precedes esterification, and the yield in the latter process can be improved by esterification at atmospheric pressure. The method is also particularly useful in synthesis of fatty acid esters of alkyl glucosides, and the results of the latter process can be improved by transesterification with fatty acid esters of lower alcohols catalyzed at temperatures at or below 180 DEG C by hypophosphite ions.
专利号:WO-2017046598-A1 优先权日:2015-09-16 标题:Treatment of acute inflammatory disorders 发明人:CRISANTI ANDREA; CANAVESE MIRIAM 权利人:CRISANTI ANDREA; IMP INNOVATIONS LTD 摘要:The present invention relates to a VEGF receptor agonist for use in the treatment of an acute inflammatory disorder associated with the overproduction of pro-inflammatory cytokine, administered with an agent that induces the synthesis of Nrf2. The invention also relates to pharmaceutical combinations comprising a VEGF receptor agonist and an agent that induces the synthesis of Nrf2, and kits comprising these agents. The described uses, combinations and methods may prevent or reduce the dis-regulated activation of an inflammatory response and reduce endothelial damage.
1: Bavol D, Economou A, Zima J, Barek J, Dejmkova H. Simultaneous determination of tert-butylhydroquinone, propyl gallate, and butylated hydroxyanisole by flow-injection analysis with multiple-pulse amperometric detection. Talanta. 2018 Feb 1;178:231-236. doi: 10.1016/j.talanta.2017.09.032. Epub 2017 Sep 12. doi: 10.1021/acs.jafc.7b04517. Epub 2017 Nov 21. doi: 10.1016/j.fct.2017.09.017. Epub 2017 Sep 9. doi: 10.1016/j.toxlet.2017.08.018. Epub 2017 Aug 24. doi: 10.1016/j.taap.2017.08.012. Epub 2017 Aug 24. doi: 10.1016/j.marenvres.2017.07.020. Epub 2017 Jul 22. doi: 10.1016/j.cbi.2017.05.021. Epub 2017 Jun 2. doi: 10.1016/j.foodchem.2017.04.176. Epub 2017 May 2. doi: 10.1080/10641963.2016.1259322. Epub 2017 May 23. doi: 10.1371/journal.pone.0176939. eCollection 2017. 11: Guo Y, Guo Y, Xie Y, Cheng Y, Qian H, Yao W. Regeneration of tert-butylhydroquinone by tea polyphenols. Food Res Int. 2017 May;95:1-8. doi: 10.1016/j.foodres.2017.02.009. Epub 2017 Feb 20. 13: Zagorski JW, Maser TP, Liby KT, Rockwell CE. Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H(2)O(2) in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing. J Pharmacol Exp Ther. 2017 May;361(2):259-267. doi: 10.1124/jpet.116.238899. Epub 2017 Mar 9.
合成参考文献
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