CAS: 127-09-3; Anhydrous Sodium Acetate

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CAS号57-55-6 丙二醇 | CAS号628-63-7 乙酸戊酯 | CAS号6131-90-4 乙酸钠,三水 | CAS号64-17-5 乙醇 | CAS号302-84-1 DL-丝氨酸 | CAS号127-17-3 丙酮酸 | CAS号74-86-2 乙炔 | CAS号116-09-6 羟基丙酮 | CAS号157977-39-4 2-Pentanone, 4-... | CAS号10475-63-5 3-氧代-2-(2-苯基亚肼基)丁酸乙酯 | CAS号10500-11-5 乙酸1-戊烯-3-基酯 | CAS号10283-52-0 (7-methoxy-2-ox... | CAS号124-38-9 二氧化碳 | CAS号64-19-7 冰醋酸 | CAS号74-89-5 氨基甲烷 | CAS号10465-27-7 SAMARIUM ACETATE | CAS号10500-10-4 acetic acid,pen... | CAS号10437-78-2 acetic acid,cyc... | CAS号76644-52-5 cyclohex-2-en-1...

专利信息

专利号:WO-2024189634-A1
优先权日:2023-03-13
标 题 :Highly atom economical process for synthesis of novel co-initiator for photo-induced radical polymerisation
发明人：KAPAT DR AJOY; AHMAD ASRAR; MITTAL GARVISHA
权利人:SHIV NADAR INSTITUTION OF EMINENCE DEEMED TO BE UNIV
摘要:The present invention relates to a base catalyzed sequential conjugate addition reaction for the synthesis of a novel and efficient co-initiator for Photo Induced Radical Polymerization. The process comprises synthesis of new co-initiator having 6,5 and 6,6-bicyclic scaffolds as central core. The process comprises reacting thiocarboxylic acid, catechol, thiocatechol, benzodithiol, benzothiocatechol and binol with ketone substrates at room temperature with a base and a solvent to yield the novel co-initiator compound of Formula 3, Formula 5, Formula C and Formula Z.

专利号:WO-2021014395-A1
优先权日:2019-07-24
标题:Process for the synthesis of deuterated capsaicin, capsaicinoids and synthetic capsaicin analogs
发明人：ORUGANTI SRINIVAS; AMRUTAPU SRAVANTH KUMAR; SAMPATH MAGESH; SEN SAIKAT
权利人:DR REDDY’S INST OF LIFE SCIENCES
摘要:The present application provides novel processes for the synthesis of deuterated intermediates of capsaicinoids, particularly II, III, IV and V of capsaicinoids, relating to pharmaceutical applications. The invention also provides novel intermediates of compounds of formula IX, XIV, XV, XVI, XVII, XVIII, XX and XXI utilized in the process of making deuterated capsaicin II, III, IV and V.

专利号:US-2025019732-A1
优先权日:2023-07-07
标 题:Method for chemical-biological cascade synthesis of l-phosphinothricin and mutants therefor
发明人：XUE YAPING; CHENG FENG; ZOU SHUPING; XU JIANMIAO; ZHENG YUGUO
权利人:UNIV ZHEJIANG TECHNOLOGY
摘要:A method for chemical-biological cascade synthesis of L-phosphinothricin is carried out as follows: 3-(methylethoxyphosphinyl) ethyl propionate is synthesized by addition reaction from diethoxymethylphosphine and acrylic acid, then a condensation reaction is carried out with 3-(methylethoxyphosphinyl) ethyl propionate and sodium ethoxide as reactants, then the product is subjected to a hydrolysis reaction with diethyl oxalate to synthesize 4-(hydroxymethylphosphinyl)-2-oxobutyric acid, and finally, L-phosphinothricin is catalytically synthesized by taking 4-(hydroxymethylphosphinyl)-2-oxobutyric acid as a raw material, and using highly active and stable wet cells co-expressing phsophinothricin dehydrogenase and alcohol dehydrogenase or co-expressing a phsophinothricin dehydrogenase mutant and alcohol dehydrogenase as a biocatalyst, thereby solving the problems of existing L-phosphinothricin synthesis being tedious, low asymmetric amination reduction activity and poor stability.

专利号:US-8779122-B2
优先权日:2012-11-08
标 题:Process for the synthesis of (2E)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
发明人：CARRANZA MARIA DEL PILAR; GARCIA ARANDA MARIA ISABEL; GONZALEZ JOSÉ LORENZO; SANCHEZ FRÉDÉRIC
权利人:SERVIER LAB
摘要:Process for the synthesis of the compound of formula (I): n nApplication in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

专利号:US-12162849-B2
优先权日:2018-12-21
标题 :Synthesis of 3-methyl-1,2,4-thiadiazole-5-carbohydrazide or of the methyl-d3 deuterated form thereof
发明人：HOVEYDA HAMID; DUTHEUIL GUILLAUME
权利人:OGEDA SA
摘要:The present invention relates to a method of synthesis of compound (I), wherein R1 represents methyl or methyl-d3, thus corresponding to 3-methyl-1,2,4-thiadiazole-5-carbohydrazide or to the methyl-d3 deuterated form thereof. These compounds are useful as key intermediates in the synthesis of pharmaceutical compounds, especially fezolinetant and deuterated fezolinetant.

专利号:US-11465970-B2
优先权日:2017-12-14
标题 :Method for synthesis of Roxadustat and intermediate compounds thereof
发明人：XU YONGXIANG
权利人:NANJING CAVENDISH BIO ENGINEERING TECH CO LTD; XU YONGXIANG; NANJING CAVENDISH BIO ENG TECH CO LTD
摘要:The present application provides a method for synthesis of Roxadustat. A compound as represented by formula (VIII) is used as a raw material, and is reacted with phenol, a vinyl-containing ether, an acid, hydroxylamine, and then the product is reacted with glycine. In addition, the present application also provides intermediate compounds as represented by formula (IX), formula (XI), formula (XII), formula (IV), and formula (V) for synthesis of Roxadustat. Herein, details of the substituents involved in formula (VIII), formula (IX), formula (XI), and formula (XII) are stated in the description