CAS: 100379-00-8; (2,6-Dimethylphenyl)Boronic Acid

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325141-72-8 5980-97-2 55499-44-0

上下游产品

CAS号121-43-7 硼酸三甲酯 | CAS号576-22-7 2-溴间二甲苯 | CAS号21450-64-6 2,6-二甲基苯基溴化镁 | CAS号139719-91-8 dimethoxy(2,6-d... | CAS号6781-98-2 2-氯间二甲苯 | CAS号608-28-6 1,3-二甲基-2-碘苯 | CAS号443-88-9 2-氟-1,3-二甲苯 | CAS号392-69-8 2,4,6-三甲基氟苯 | CAS号2039-90-9 2-乙烯基-1,3-二甲基苯 | CAS号105337-15-3 ethyl 2-(2,6-di... | CAS号108-38-3 间二甲苯 | CAS号10273-87-7 1,3-dimethyl-2-... | CAS号87-62-7 2,6-二甲基苯胺 | CAS号576-26-1 2,6-二甲基苯酚 | CAS号81-20-9 2,6-二甲基硝基苯

2-氯-1,3-二甲苯置于四羟基二硼,氯(2-二环己基膦基-2',4',6'-三异丙基-1,1'-联苯基)[2-(2'-氨基-1,1'-联苯)]钯(II),Potassium Acetate,2-二环己基磷-2,4,6-三异丙基联苯体系中,用 乙醇 用作溶剂,化学反应 4.5H,反应生成2,6-二甲基苯硼酸
参考文献:使用双硼酸的钯催化芳基硼化反应的范围
标题:使用双硼酸的钯催化芳基硼化反应的范围
摘要:Suzuki-Miyaura 反应已成为合成有机化学家更有用的工具之一.直到最近,还没有直接的方法来制造偶联反应中最重要的成分,即硼酸.目前制造硼酸的方法通常使用苛刻或浪费的试剂来制备硼酸衍生物,并且需要额外的步骤来提供所需的硼酸.先前报道的钯催化的直接硼酸合成的范围被揭开,其中包括广泛的合成有用的芳基亲电试剂.它利用新推出的第二代 Buchwald Xphos 预制钯催化剂和双硼酸.为了便于隔离并保留通常敏感的 Cb 键,
Doi:10.1021/ja303181M

专利信息

专利号:US-7205427-B2
优先权日:2002-06-04
标 题:Cross-coupling synthesis of alkyl (dialkylphenyl) indenes
发明人：BARNES HAMLIN H
权利人:BOULDER SCIENT CO
摘要:A cross-coupling synthesis of 2-alkyl-4-(2,6-dialkylphenyl)indenes is described. A 2-alkylidene is treated with a dialkylboronic acid in the presence of a catalyst. A feature of the invention is the use of a cross-coupling catalyst comprising palladium dichloride (1,5-cyclooctadiene) as a cross-coupling catalyst.

专利号:US-8212056-B2
优先权日:2008-06-30
标 题 :Ligands for transition-metals and methods of use
发明人：KWONG FUK YEE; SO CHAU MING
权利人:KWONG FUK YEE; SO CHAU MING; UNIV HONG KONG POLYTECHNIC
摘要:The present invention relates to indolyl phosphine ligands, and methods of making such ligands utilizing phenyl hydrazines and aryl ketones as the starting material. The present invention further includes uses of the ligands in the synthesis of pharmaceuticals, materials, and agriculture.

专利号:US-2023365629-A1
优先权日:2018-06-15
标题:Synthesis of echinocandin antifungal agent

专利号:US-8853228-B2
优先权日:2007-06-04
标 题:Heterocyclic analogs of propargyl-linked inhibitors of dihydrofolate reductase
发明人：ANDERSON AMY C; WRIGHT DENNIS L; FREY KATHLEEN MARY; PAULSEN JANET LEIGH; SCOCCHERA ERIC WILLIAM; VISWANATHAN KISHORE
权利人:ANDERSON AMY C; WRIGHT DENNIS L; FREY KATHLEEN MARY; PAULSEN JANET LEIGH; SCOCCHERA ERIC WILLIAM; VISWANATHAN KISHORE; UNIV CONNECTICUT
摘要:The compositions and methods described herein disclose the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substituted aryl, bicyclo or heteroaryl ring. These DHFR inhibitors are potent and selective for many different pathogenic organisms, including the DHFR enzyme from bacteria such as Bacillus anthracis and methicillin-resistant Staphylococcus aureus , fungi such as Candida glabrata, Candida albicans and Cryptococcus neoformans and protozoa such as Cryptosporidium hominis and Toxoplasma gondii . These compounds and other similar compounds are also potent against the mammalian enzyme and may be useful as anti-cancer therapeutics.

专利号:WO-2009073246-A1
优先权日:2007-12-06
标 题 :Method for the synthesis of iridium (iii) complexes with sterically demanding ligands

专利号:US-8426432-B2
优先权日:2007-06-04
标 题 :Inhibitors of dihydrofolate reductase with antibacterial antiprotozoal, antifungal and anticancer properties
发明人：ANDERSON AMY C; WRIGHT DENNIS L; PELPHREY PHILLIP M; JOSKA TAMMY M; BOLSTAD ERIN S D; BOLSTAD DAVID B; POPOV VELJKO
权利人:ANDERSON AMY C; WRIGHT DENNIS L; PELPHREY PHILLIP M; JOSKA TAMMY M; BOLSTAD ERIN S D; BOLSTAD DAVID B; POPOV VELJKO; UNIV CONNECTICUT
摘要:The compositions and methods described herein discloses the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substituted aryl, bicyclo or heteroaryl ring. These DHFR inhibitors are potent and selective for many different pathogenic organisms, including the DHFR enzyme from bacteria such as Bacillus anthracis and methicillin-resistant Staphylococcus aureus , fungi such as Candida glabrata, Candida albicans and Cryptococcus neoformans and protozoa such as Cryptosporidium hominis and Toxoplasma gondii . These compounds and other similar compounds are also potent against the mammalian enzyme and may be useful as anti-cancer therapeutics.