CAS: 95617-09-7; 2-(4-((6-Chlorobenzo[d]Oxazol-2-yl)Oxy)Phenoxy)Propanoic Acid

该化合物是一种选择性除草剂,主要用于控制各种作物,特别是大米和小麦田的草杂草;它属于除草剂的丙氧苯氧丙基丙烯类,其作用是抑制对植物中脂肪酸合成至关重要的酶乙基-CoA carboxylase;它的特征是系统性行动,允许其被花叶吸收,并在整个植物中转植,有效地针对积极种植的杂草;它通常用于繁殖后期,使其对各种年生和常年的草种有效;它以相对较低的对哺乳动物和鸟类毒性而著称,在按照建议的准则使用时,它有助于其有利的环境特征;此外,Fenoxaprop通常与其他除草剂或粘附剂一起配制,以提高其功效并扩大其控制范围;它在整个植物中长期存在,并受到土壤和水中的微生物活动的影响.

结构式图片

欧盟法规

C&L通报

上下游产品

4-(6-Chlorobenzoxazolyloxy)Phenoxypropionic Acid Methyl Ester 66546-20-1
恶唑禾草灵 Fenoxaprop-Ethyl 66441-23-4
4-[(6-氯-1,3-苯并恶唑-2-基)氧基]苯酚 4-(6-Chlorobenzo[d]Oxazol-2-Yloxy)Phenol 70217-01-5

合成工艺路线路线简述

  • 66441-23-4 = 95617-09-7
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; Cooled; 5 - 6 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,Rt
    标题:Preparation Of Quaternary Ammonium Salts For Weed Control
    参考文献:China]

    66441-23-4 = 95617-09-7
    反应条件:1.1 Reagents: Sodium Hydroxide
    标题:Preparation Of Cyhalothrin Derivatives And Related Compounds As Agricultural Chemicals
    参考文献:World Intellectual Property Organization]

    66441-23-4 = 95617-09-7 [标题:Reaction Conditions
    标题:Metabolism Of The Herbicide Hoe 33171 In Soybeans
    作者:Wink,Ottmar; Dorn,Erich; Beyermann,Klaus
    参考文献:Journal Of Agricultural And Food Chemistry 日期:1984 卷标:32(3) 页码:187-92]

    = 95617-09-7 [标题:Reaction Conditions
    标题:Synthesis And Biological Evaluation Of Some Bioisosteres And Congeners Of The Antitumor Agent,2-{4-[(7-Chloro-2-Quinoxalinyl)Oxy]Phenoxy}Propionic Acid (Xk469)
    作者:Hazeldine,Stuart T.; Polin,Lisa; Kushner,Juiwanna; White,Kathryn; Bouregeois,Nicole M.; Et Al
    参考文献:Journal Of Medicinal Chemistry 日期:2002 卷标:45(14) 页码:3130-3137]

    66546-20-1 = 95617-09-7
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; Cooled; Rt; 5 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5
    标题:6-Chlorobenzoxazolyloxyphenoxypropionamide Compound As Weedicide And Its Preparation
    参考文献:China]

    66546-20-1 = 95617-09-7
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; Cooled; 5 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Acidified,Rt
    标题:Allyl 6-Chlorinated Benzoxazolyl-Oxy Phenoxypropionate Compounds As Herbicides And Their Preparation
    参考文献:China]

    71283-80-2 = 95617-09-7 [标题:Reaction Conditions
    标题:Fragment Recombination Design,Synthesis,And Safener Activity Of Novel Ester-Substituted Pyrazole Derivatives
    作者:Jia,Ling; Gao,Shuang; Zhang,Yuan-Yuan; Zhao,Li-Xia; Fu,Ying; Et Al
    参考文献:Journal Of Agricultural And Food Chemistry 日期:2021 卷标:69(30) 页码:8366-8379]

    66546-20-1 = 95617-09-7
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; Cooled; Rt; 5 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 4 - 5,Rt
    标题:6-Chlorobenzoxazole(Benzothiazole) Oxyphenoxypropionate Compounds As Herbicides And Their Preparation
    参考文献:China]

    256412-89-2 = 95617-09-7 + 70217-01-5 + 61110-50-7 + 59-49-4 + 19932-84-4 + 256412-88-1 + 1257227-64-7 + 1257227-65-8 + 1978-38-7 + 94050-90-5 + 227197-72-0
    反应条件:1.1 Solvents: Acetonitrile,Water; 4 H
    标题:Photodegradation Pathways And Mechanisms Of The Herbicide Metamifop In A Water/acetonitrile Solution
    作者:Moon,Joon-Kwan; Kim,Jeong-Han; Shibamoto,Takayuki
    参考文献:Journal Of Agricultural And Food Chemistry 日期:2010 卷标:58(23) 页码:12357-12365
📜2-(4-羟苯氧基)丙酸甲酯置于sodium Hydroxide,Potassium Carbonate体系中,用 四氢呋喃,乙腈 作为反应溶剂,化学反应生成 恶唑禾草灵
参考文献:二.抗肿瘤药2-(4-[(7-氯-2-喹喔啉基)氧基]苯氧基)丙酸(xk469)的一些生物等排体和同类物的合成和生物学评估.
标题:二.抗肿瘤药2-(4-[(7-氯-2-喹喔啉基)氧基]苯氧基)丙酸(xk469)的一些生物等排体和同类物的合成和生物学评估.
摘要:Xk469(1)是我们实验室中评估的最高度和最广泛活性的抗肿瘤药物之一.随后的开发研究导致(R)-(+)1(nsc 698215)进入1期临床试验(nih Uo1-Ca62487).1的抗肿瘤作用机理尚待阐明,这促使人们不断努力拟订1的药效学模式.本研究的重点是对喹喔啉部分中基于拓扑的生物等位替代物进行合成和生物学评估的策略.铅化合物(1)由喹唑啉(4A-D),1,2,4-苯并三嗪(12A-18B)和喹啉(21A-G)环系统合成.对每个1的生物等排体的合成方法都采用了先前工作中开发的方法(请参见st的hazeldine; L.的polin; J.的kushner; J.的paluch; J.的white; K.Edelstein; M.的palomino,E .; Th,Corbett;horwitz,Jp设计,合成和抗肿瘤药2-(4-[(7-氯-2-喹喔啉基)氧基]苯氧基)丙酸(xk469)类似物的生物学评估.j
DOI:10.1021/jm0200097

海关参考信息

专利信息


专利号:WO-2024256370-A1
优先权日:2023-06-13
标 题 :Synthesis of glufosinate using an amidase-based process
发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

专利号:US-2025120400-A1
优先权日:2021-12-10
标题:Synthesis of glufosinate using a hydantoinase-based process
发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

专利号:US-11919928-B2
优先权日:2016-03-16
标题 :Method for producing dihydrotentoxin
发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
权利人:KUMIAI CHEMICAL INDUSTRY CO
摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

专利号:US-2021386068-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

专利号:US-2021352899-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

专利号:ES-2717283-T3
优先权日:2012-07-24
标 题:Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and herbicides inhibitors of VLCFA synthesis and synthesis of fatty acids / lipids

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1007/s00894-011-1169-2
摘要:Singh DV, Adeppa K, Misra K. Mechanism of isoproturon resistance in Phalaris minor: in silico design, synthesis and testing of some novel herbicides for regaining sensitivity. Journal of Molecular Modeling. 2011 Jul 15;18(4):1431–45. doi: 10.1007/s00894-011-1169-2.
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