CAS: 83-95-4; 4,7,8-Trimethoxyfuro[2,3-B]Quinoline

该化合物是精液,其特点是分子结构复杂,包括双环框架,其特点是分子结构复杂,包括双环框架. 硅碱展示了一系列生物活动,包括抗微生物,抗炎和潜在的抗癌特性,从而引起了对药理研究的兴趣.该化合物通常以白到苍白黄色晶状固体的形式出现,溶于有机溶剂,但水溶解度有限.其化学特性包括一种基本性质,因为其结构中存在氮,允许其形成酸盐. 正在探索其潜在的治疗应用,特别是在传统医学中,因为传统医学已经用于其所谓的健康利益.然而,有必要开展进一步研究,以充分了解其在各种生物环境中的行动和功效机制.

结构式图片

物理性质

MSDS等安全信息

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C&L通报

上下游产品

CAS号186581-53-3 重氮甲烷 | CAS号865878-27-9 4-chloro-7,8-di... | CAS号124-41-4 甲醇钠 | CAS号110548-95-3 chaplophytin-B | CAS号5876-17-5 单叶芸香品碱 | CAS号77-78-1 硫酸二甲酯 | CAS号62580-17-0 4,7-dimethoxyfu... | CAS号23417-92-7 7-异戊烯氧基-GAMMA-花椒碱 | CAS号81536-07-4 4,7-dimethoxy-8... | CAS号5876-17-5 单叶芸香品碱

合成工艺路线路线简述

  • 合成目标产物 Skimmianine 主要起始原料 1-(4,8-Dimethoxy-Furo[2,3-B]Quinolin-7-Yloxy)-3-Methyl-Butane-2,3-Diol
  • 865878-27-9 = 83-95-4 [标题:Reaction Conditions
    标题:Cis-Dihydrodiol,Arene Oxide And Phenol Metabolites Of Dictamnine: Key Intermediates In The Biodegradation And Biosynthesis Of Furoquinoline Alkaloids
    作者:Boyd,Derek R.; Et Al
    参考文献:Chemical Communications (Cambridge 日期:2005 卷标:(31) 页码:3989-3991]

    865878-26-8 = 83-95-4 [标题:Reaction Conditions
    标题:Cis-Dihydrodiol,Arene Oxide And Phenol Metabolites Of Dictamnine: Key Intermediates In The Biodegradation And Biosynthesis Of Furoquinoline Alkaloids
    作者:Boyd,Derek R.; Et Al
    参考文献:Chemical Communications (Cambridge 日期:2005 卷标:(31) 页码:3989-3991]

    865878-14-4 = 83-95-4
    反应条件:1.1 Catalysts: Cis-1,2-Dihydro-1,2-Dihydroxynaphthalene Dehydrogenase2.1 -
    标题:Cis-Dihydrodiol,Arene Oxide And Phenol Metabolites Of Dictamnine: Key Intermediates In The Biodegradation And Biosynthesis Of Furoquinoline Alkaloids
    作者:Boyd,Derek R.; Et Al
    参考文献:Chemical Communications (Cambridge 日期:2005 卷标:(31) 页码:3989-3991]

    119188-51-1 = 83-95-4 [标题:Reaction Conditions
    标题:Cis-Dihydrodiol,Arene Oxide And Phenol Metabolites Of Dictamnine: Key Intermediates In The Biodegradation And Biosynthesis Of Furoquinoline Alkaloids
    作者:Boyd,Derek R.; Et Al
    参考文献:Chemical Communications (Cambridge 日期:2005 卷标:(31) 页码:3989-3991]

    484-29-7 = 83-95-4
    反应条件:1.1 Reagents: Oxygen Catalysts: Biphenyl 2,3-Dioxygenase2.1 Catalysts: Cis-1,2-Dihydro-1,2-Dihydroxynaphthalene Dehydrogenase3.1 -
    标题:Cis-Dihydrodiol,Arene Oxide And Phenol Metabolites Of Dictamnine: Key Intermediates In The Biodegradation And Biosynthesis Of Furoquinoline Alkaloids
    作者:Boyd,Derek R.; Et Al
    参考文献:Chemical Communications (Cambridge 日期:2005 卷标:(31) 页码:3989-3991]

    865878-17-7 = 83-95-4
    反应条件:1.1 Catalysts: Cis-1,2-Dihydro-1,2-Dihydroxynaphthalene Dehydrogenase2.1 -3.1 -
    标题:Cis-Dihydrodiol,Arene Oxide And Phenol Metabolites Of Dictamnine: Key Intermediates In The Biodegradation And Biosynthesis Of Furoquinoline Alkaloids
    作者:Boyd,Derek R.; Et Al
    参考文献:Chemical Communications (Cambridge 日期:2005 卷标:(31) 页码:3989-3991]

    111163-82-7 = 83-95-4
    反应条件:1.1 Reagents: Oxygen Catalysts: Biphenyl 2,3-Dioxygenase2.1 Catalysts: Cis-1,2-Dihydro-1,2-Dihydroxynaphthalene Dehydrogenase3.1 -4.1 -
    标题:Cis-Dihydrodiol,Arene Oxide And Phenol Metabolites Of Dictamnine: Key Intermediates In The Biodegradation And Biosynthesis Of Furoquinoline Alkaloids
    作者:Boyd,Derek R.; Et Al
    参考文献:Chemical Communications (Cambridge 日期:2005 卷标:(31) 页码:3989-3991
📜Evoxine置于氢氧化钾,水体系中,化学反应生成 4,7,8-三甲氧基呋喃并[2,3-B]喹啉
参考文献:Eastwood Et Al.,Australian Journal Of Chemistry,1954,Vol. 7,P. 87,93
标题:Eastwood Et Al.,Australian Journal Of Chemistry,1954,Vol. 7,P. 87,93

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主要参考文献


1: Gotsurve KN, Das J, Kutre S, Teja PK, Rathod R, Chauthe SK, Behera SK. In- silico and In-vitro Investigation of Flavonoids and Alkaloids from Artocarpus heterophyllus, Tinospora cordifolia, and Glycosmis pentaphylla as Potential NF- κB Inhibitors in Oral Cancer. Chem Biodivers. 2024 Oct
10:e202401886. doi: 10.1002/cbdv.202401886. Epub ahead of print.
733:150685. doi: 10.1016/j.bbrc.2024.150685. Epub 2024 Sep 11. 16(8):1346. doi: 10.3390/v16081346.

合成参考文献


参考文献:10.1021/np980471n
摘要:Chen IS, Chen TL, Chang YL, Teng CM, Lin WY. Chemical constituents and biological activities of the fruit of Zanthoxylum integrifoliolum. J Nat Prod. 1999 Jun;62(6):833–7. doi: 10.1021/np980471n.
参考文献:10.1016/s0031-9422(01)00186-8
摘要:Pacher T, Bacher M, Hofer O, Greger H. Stress induced carbazole phytoalexins in Glycosmis species. Phytochemistry. 2001 Sep;58(1):129–35. doi: 10.1016/s0031-9422(01)00186-8.
参考文献:10.1021/np0106182
摘要:Muriithi MW, Abraham W-, Addae-Kyereme J, Scowen I, Croft SL, Gitu PM, Kendrick H, Njagi ENM, Wright CW. Isolation and in Vitro Antiplasmodial Activities of Alkaloids from Teclea trichocarpa: In Vivo Antimalarial Activity and X-ray Crystal Structure of Normelicopicine. J. Nat. Prod. 2002 Jun 13;65(7):956–9. doi: 10.1021/np0106182.
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