CAS: 367-11-3; 1,2-Difluorobenzene

上下游产品

CAS号348-54-9 邻氟苯胺 | CAS号139-87-7 N-乙基二乙醇胺 | CAS号36556-47-5 2,3-二氟氯苯 | CAS号348-51-6 2-氯氟苯 | CAS号528-29-0 1,2-二硝基苯 | CAS号352-33-0 对氯氟苯 | CAS号696-02-6 4-氯-1,2-二氟苯 | CAS号252936-43-9 4-chloro-4,5,5-... | CAS号462-06-6 氟苯 | CAS号455-86-7 3,4-二氟苯甲酸 | CAS号455-38-9 间氟苯甲酸 | CAS号369-34-6 3,4-二氟硝基苯 | CAS号455-93-6 2-氟-4-硝基苯甲醚 | CAS号385380-74-5 1-(2-氟-4-硝基苯基)四氢吡咯 | CAS号372-18-9 1,3-二氟苯 | CAS号540-36-3 1,4-二氟苯 | CAS号462-06-6 氟苯 | CAS号71-43-2 苯 | CAS号369-33-5 3,4-二氟苯乙酮

1,2-二硝基苯置于四丁基氟化铵体系中,用 二甲基亚砜 用作溶剂,化学反应 0.17H,以95%的收率获得1,2-二氟苯
参考文献:Microwave-Accelerated Fluorodenitrations And Nitrodehalogenations: Expeditious Routes To Labeled Pet Ligands And Fluoropharmaceuticals
标题:Microwave-Accelerated Fluorodenitrations And Nitrodehalogenations: Expeditious Routes To Labeled Pet Ligands And Fluoropharmaceuticals
摘要:Methods For The Expeditious Fluorination Of Arenes Have Been Investigated,Using Readily Available Fluoride Sources. An Optimized Procedure For Microwave-Accelerated Fluorodenitration Has Been Developed,Giving Good To Excellent Yields In Less Than 10 Min,Rendering It Practical For Use In The Preparation Of F-18 Labeled Ligands For Pet Imaging. Application Of The Method In The Synthesis Of Cns Agents Is Demonstrated,And A Practical Method For The Preparation Of Substrates Is Also Presented. (C) 2010 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2010.02.042

专利信息

专利号:US-2021107859-A1
优先权日:2018-04-06
标题 :A process for the synthesis of carbon labeled organic compounds
发明人：AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.

专利号:US-2010016607-A1
优先权日:2006-12-11
标题:Process for the Synthesis of Highly Active Binary Metal Fluoride as a Fluorinating Agent for Aromatics
发明人：DOLBIER JR WILLIAM R; JANMANCHI KRISHNA MURTHY
权利人:UNIV FLORIDA
摘要:The subject invention relates to a process for the synthesis of highly active binary metal fluoride system for the fluorination of aromatic compounds. Fluorinated aromatic compounds are valuable synthons for the chemical synthesis of pharmaceutical drugs and novel polymers. Fluorobenzene is used to control carbon content in steel manufacturing, is an intermediate for pharmaceuticals, pesticides and other organic compounds. Fluorobenzene is typically produced by the reaction of aniline and sodium nitrite in the presence of hydrogen fluoride. The present invention relates to a process for the synthesis of highly active binary metal fluoride system consists of copper (II) fluoride and aluminum (III) fluoride for the fluorination of aromatic compounds in gas phase and recycling of the reagent, in situ, using O 2 and HF.

专利号:US-5512701-A
优先权日:1995-06-07
标题:Process for the synthesis of vinyl sulfenic acid derivatives
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.

专利号:EP-2644590-A1
优先权日:2012-03-30
标 题:Synthesis of 2-(3,4-difluorophenyl)cyclopropanamine derivatives and salts
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

专利号:EP-2570405-A1
优先权日:2011-09-14
标题:Synthesis of Triazolopyrimidine Compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the filed of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of ticagrelor (TGC)

专利号:US-10731001-B2
优先权日:2018-11-09
标 题 :Method for the recovery of compounds deriving from the synthesis of poly aryl ether ketone polymers
发明人：SCHON STEVEN GABRIEL; GODDARD ANDREW RICHARD; JOUANNEAU JULIEN
权利人:ARKEMA FRANCE
摘要:A method for treating a shear-thinning residue composition deriving from the synthesis of an aryl ether ketone, the residue composition including a liquid fraction and solid residues, the method including the steps of: passing said shear-thinning residue composition through a shear-generating evaporating device, between a rotating part and a stationary part; and recovering a condensed liquid fraction and separately recover concentrated solid residues.