2,5-二溴吡啶置于正丁基锂,氯化亚砜,三乙胺体系中,用 甲苯 用作溶剂,化学反应 7.0H,反应生成5-溴吡啶-2-羧酸甲酯
参考文献:Ligand Creation Via Linking-a Rapid And Convenient Method For Construction Of Novel Supported Pyox-Ligands
标题:Ligand Creation Via Linking-a Rapid And Convenient Method For Construction Of Novel Supported Pyox-Ligands
摘要:A Novel Supported Amino Alcohol Linker Was Synthesized And Utilized For Attachment Of Picolinic Acid Derivatives Onto Different Supports. When The Resin Bound Molecule Was Further Activated,The Pyox-Moiety Could Be Constructed Reliably In Enantiopure Form. Furthermore,An Efficient Pd-Catalyzed Modification Of A Picolinic Acid Derivative Is Presented. (C) 2005 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tet.2005.08.073