CAS: 288067-35-6; 4-Bromo-2-Hydroxybenzonitrile

上下游产品

CAS号105942-08-3 4-溴-2-氟苯腈 | CAS号330793-38-9 4-溴-2-甲氧基苯腈 | CAS号179897-89-3 5-溴-2-氟苯腈 | CAS号30186-18-6 4-溴-2-羟基苯乙酮

📜4-溴-2-甲氧基苯腈置于aluminum (III) Chloride体系中,用 二氯甲烷 用作溶剂,以95.2%的收率获得4-溴-2-氰基苯酚
参考文献: Benzofuran And Benzothiophene Derivatives Useful In The Treatment Of Hyper-Proliferative Disorders[fr] Derives De Benzofurane Et De Benzothiophene Utilises Dans Le Traitement De Troubles Hyperproliferatifs
标题: Benzofuran And Benzothiophene Derivatives Useful In The Treatment Of Hyper-Proliferative Disorders[fr] Derives De Benzofurane Et De Benzothiophene Utilises Dans Le Traitement De Troubles Hyperproliferatifs
摘要:这项发明涉及一般式的新型苯并呋喃和苯并噻吩衍生物及其用于治疗高增殖性疾病的用途.

专利信息

专利号:US-8178559-B2
优先权日:2004-12-30
标 题:Organic compounds
发明人：BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI
权利人:BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula (I), wherein the symbols have the meanings defined in the specification.

专利号:CN-114249680-B
优先权日:2022-01-10
标 题:A kind of indole derivative and its synthesis method and application