CAS: 274-07-7; Benzcatechinborane

上下游产品

CAS号120-80-9 邻苯二酚 | CAS号37737-62-5 O-亚苯基硼酸盐 | CAS号13826-27-2 双(邻苯二酚)二硼酸酯 | CAS号16940-66-2 硼氢化钠 | CAS号172266-59-0 | CAS号71-43-2 苯 | CAS号172266-60-3 | CAS号121589-95-5 2-(2'-methylami... | CAS号3602-36-6 bis(benzo-1,3,2... | CAS号13292-87-0 硼烷二甲硫醚 | CAS号106094-36-4 (E)-2-(1-Buteny... | CAS号107648-56-6 (Z)-3-Hexenyl-3... | CAS号454-91-1 1-甲基-3-三氟甲基苯乙醇 | CAS号37737-62-5 O-亚苯基硼酸盐 | CAS号6125-24-2 Β-硝基苯乙烷 | CAS号374-01-6 1,1,1-三氟-2-丙醇 | CAS号2240-88-2 3,3,3-三氟丙-1-醇 | CAS号98-85-1 苏合香醇 | CAS号60-12-8 苯乙醇

双联邻苯二酚硼酸酯置于palladium 10% On Activated Carbon,氢气体系中,用 正戊烷 用作溶剂,20.0 °C,100.0 Kpa 条件下,反应 21.0H,以26%的收率获得儿萘酚硼烷
参考文献:儿茶酚,Pinacol-和neopentylglycolborane的合成通过多相催化乙b乙硼烷的氢解(4)
标题:儿茶酚,Pinacol-和neopentylglycolborane的合成通过多相催化乙b乙硼烷的氢解(4)
摘要:已开发出一种新的合成方法来处理氢硼烷邻苯二酚,频哪醇和新戊二醇硼烷.从乙硼烷(4)乙开始2猫2,B 2销2,或b 2 Neop 2,是由b的非均相催化裂解获得的各个硼烷与氢的相应乙硼烷乙键.发现第10族金属是该反应的有效催化剂.
Doi:10.1002/chem.201302677

专利信息

专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:US-2008032964-A1
优先权日:2006-04-10
标题:Process for the synthesis of azetidinone
发明人：KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
权利人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
摘要:Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.

专利号:US-9388131-B2
优先权日:2011-04-27
标题:Automated synthesis of small molecules using chiral, non-racemic boronates
发明人：BURKE MARTIN D; LI JUNQI; GILLIS ERIC P
权利人:UNIV ILLINOIS
摘要:Provided are methods for making and using chiral, non-racemic protected organoboronic acids, including pinene-derived iminodiacetic acid (PIDA) boronates, to direct and enable stereoselective synthesis of organic molecules. Also provided are methods for purifying PIDA boronates from solution. Also provided are methods for deprotection of boronic acids from their PIDA ligands. The purification and deprotection methods may be used in conjunction with methods for coupling or otherwise reacting boronic acids. Iterative cycles of deprotection, coupling, and purification can be performed to synthesize chiral, non-racemic compounds. The methods are suitable for use in an automated chemical synthesis process. Also provided is an automated small molecule synthesizer apparatus for performing automated stereoselective synthesis of chiral, non-racemic small molecules using iterative cycles of deprotection, coupling, and purification.

专利号:US-2004018598-A1
优先权日:2000-05-30
标题 :Bio-intermediates for use in the chemical synthesis of polyketides
发明人：SANTI DANIEL; ASHLEY GARY; MYLES DAVID C
摘要:The present invention relates to compounds made by a subset of modules from one or more polyketide synthase (“PKSâ€?) genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring polyketides or derivatives thereof. The biologically derived intermediates (“bio-intermediatesâ€?) generally represent particularly difficult compounds to synthesize using traditional chemical approaches due to one or more stereocenters. In one aspect of the invention, an intermediate in the synthesis of epothilone is provided that feeds into the synthetic protocol of Danishefsky and co-workers. In another aspect of the invention, intermediates in the synthesis of discodermolide are provided that feed into the synthetic protocol of Smith and co-workers. By taking advantage of the inherent stereochemical specificity of biological processes, the syntheses of key intermediates and thus the overall syntheses of compounds like epothilone and discodermolide are greaty simplified.

专利号:US-10889599-B2
优先权日:2018-02-27
标 题:1,1-diborylalkyl-1-metal compounds, preparation method thereof, and their applications toward synthesis of 1,1-diboronate ester compounds
发明人：CHO SEUNG HWAN; LEE YEOSAN
权利人:POSTECH ACAD IND FOUND
摘要:The present invention relates to a 1,1-diborylalkyl-1-metal compound including one metal group together with two identical boron groups at the sp3 carbon center, and its use. Specifically, the present invention relates to development of novel organic reactions, synthesis of functional molecules, and synthesis of new drugs by applying the novel 1,1-diboryl-1-metal substituted alkyl compounds to various molecular libraries which could not be synthesized by conventional methodologies.

专利号:US-5476915-A
优先权日:1994-06-29
标题:Method for controlled synthesis of polymers
发明人：SHEA KENNETH J; WALKER JAMES R; ZHU HIUDE
权利人:UNIV CALIFORNIA
摘要:Living polymer synthesis methods for the synthesis of oligomeric and high molecular weight polymers with low polydispersity are disclosed. The disclosed methods are based on the discovery that the reaction of a ylid with an organoborane at a high ylid:borane ratio and high temperature provides for the synthesis of high molecular weight polymers with low polydispersity.