CAS: 19492-03-6; 8-Hydroxy-7-Methoxy-2H-Chromen-2-One

该化合物是一种替代的 Coumarin衍生物,在有机合成和光化学中具有显著应用,其结构以氢氧基和甲基氧功能组为特征,增强了其作为荧光探测器或生物活性化合物合成中间体的回活动性和实用性.该化合物具有很强的紫外线吸收和荧光特性,对分析和光谱研究很有价值.在标准条件下的稳定性和明确界定的化学行为进一步增强了其在研究环境中的可靠性.此外,其衍生潜力允许根据特定实验需求进行量身定制的修改,强调其在合成和材料科学应用中的多功能性.

英文名称8-Hydroxy-7-Methoxy-2H-Chromen-2-One
中文名称瑞香素-7-甲醚
IUPAC名称8-hydroxy-7-methoxy-2H-chromen-2-one
其它别名Coumarin,8-hydroxy-7-methoxy- (7CI,8CI); Herniarin, 8-hydroxy- (6CI); 7-Methoxy-8-hydroxycoumarin; 8-Hydroxy-7-methoxycoumarin; Daphnetin 7-methylether
CAS编号19492-03-6
MFCD编号:MFCD00075652
EINECS号:681-517-4
FDA UNII编号:H43B8D33LB
分子式:C10H8O4分子量:192.17
产品CID: 989834
产品分类医药中间体 → 吡喃类化合物

相似结构搜索
产品信息参考;;;;
InChIKey: KIGCGZUAVODHMD-UHFFFAOYSA-N
InChI=1S/C10H8O4/c1-13-7-4-2-6-3-5-8(11)14-10(6)9(7)12/h2-5,12H,1H3
计算化学: 氢键受体数4.0氢键供体数1.0可旋转键数1.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H315-H319-H335
防范说明P280g-P305+P351+P338
安全声明26-36
危险类别码36/37/38

上下游产品

diazomethane 8-acetoxy-7-hydroxycoumarin 7-methoxy-8-coumarinul methyl ketone 2,3-dihydroxy-4-methoxybenzaldehyde 7,8-dimethoxy-chromen-2-one 7-methoxy-8-[(3-methyl-2-butenyl)oxy]-2H-1-benzopyran-2-one daphnetin

合成工艺路线路线简述

📜瑞香素置于甲醇,乙醚,乙酰氯体系中,化学反应生成瑞香素-7-甲醚
参考文献:Gandini,Gazzetta Chimica Italiana,1940,Vol. 70,P. 611,613
标题:Gandini,Gazzetta Chimica Italiana,1940,Vol. 70,P. 611,613

海关参考信息

2905110000-甲醇
2907210001-间苯二酚
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9440940-B2
优先权日:2014-03-18
标题:Methods for synthesis of psoralen derivatives
发明人：REFOUVELET BERNARD
权利人:MACOPHARMA S A S
摘要:Methods for the synthesis of psoralen derivatives are provided. In one embodiment, the method may include acetylating a compound of formula (II) to form a compound of formula (III), subjecting the compound of formula (III) to a Fries rearrangement to form a compound of formula (IV), and subjecting the compound of formula (IV) to cyclization, reduction and aromatization, to form a compound having the following formula (I):

专利号:US-2015266845-A1
优先权日:2014-03-18
标题 :Methods for synthesis of psoralen derivatives