CAS: 17689-17-7; 6-Mercaptohexanoic Acid

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6-bromohexanoic acid 6-hydroxy-hexanoic acid ethyl ester thiourea hexahydro-2H-oxepin-2-one 6,6'-disulfanediyldihexanoic acid 6-(2,4-dinitro-phenyldisulfanyl)-hexanoic acid 6-(2-nitro-phenyldisulfanyl)-hexanoic acid 1-mercapto-5-carbomethoxy-pentane

📜6-[(4-Methoxyphenyl)-Diphenylmethyl]Sulfanylhexanoic Acid置于2-[[三(羟甲基)甲基]氨基]乙磺酸,三氟乙酸体系中,用 二氯甲烷 用作溶剂,化学反应 5.0H,反应生成6-巯基己酸
参考文献:S-4-Methoxytrityl Mercapto Acids: Synthesis And Application
标题:S-4-Methoxytrityl Mercapto Acids: Synthesis And Application
摘要:4-Methoxytrityl (Mmt)-Mercapto Acids Were Obtained Either By The Reaction Of Mercapto Acids With Mmt-Chloride Or By The Reaction Of Halo Acids With Mmt-Thiol. The Derivatives Obtained Were Used In The Solid-Phase Synthesis Of Small Libraries Of Mercaptoacylamino Acids And Mercaptoacyl Peptides. The Removal Of The Mmt-Group Was Performed By Treatment With Trifluoroacetic Acid (Tfa) In Dichloromethane (Dcm) Using Triethylsilane (Tes) As Scavenger. (C) 2001 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0040-4039(01)01423-X

专利信息

专利号:US-8835477-B2
优先权日:2009-10-06
标题 :Method for the synthesis of 2-thiohistidine and the like
发明人：ERDELMEIER IRÈNE; DAUNAY SYLVAIN
权利人:ERDELMEIER IRÈNE; DAUNAY SYLVAIN; TETRAHEDRON
摘要:Methods for the synthesis of 2-thiohistidine or a derivative thereof of the formula (I), or of a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, from a compound of the formula (II) or a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, by cleavage reaction in the presence of a thiol at a temperature higher than or equal to 60° C. The invention also relates to compounds of the formula (II) and a method for the synthesis thereof.

专利号:US-11180507-B2
优先权日:2016-07-08
标题:Synthesis of functionalizable or functionalized poly(3,4-ethylenedioxythiphene)-based polymers and monomers therefor
发明人：CUI XINYAN; CAO BIN
权利人:UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION; UNIV OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
摘要:A method of forming a compound having the formula (I′): (I′) includes the reaction: (II′) in the presence of a base, wherein X is a halo atom selected from the group consisting of Cl, Br and I.

专利号:US-2015328616-A1
优先权日:2014-05-13
标题:Surface mediated synthesis of polynucleotides, polypeptides and polysaccharides and related materials, methods and systems
发明人：GETHERS MATTHEW; GODDARD III WILLIAM A; WEISS PAUL S; RANDALL JOHN
权利人:CALIFORNIA INST OF TECHN
摘要:Surface mediated polymer synthesizing methods and related systems and materials are described where monomers are attached to monomer binding regions on a surface and subsequently form chemical bonds with adjacent monomers on the surface to form linear polymers selected from polynucleotide, polypeptides and polysaccharides.

专利号:US-9375790-B2
优先权日:2012-07-26
标题:Continuous flow reactor and method for nanoparticle synthesis
发明人：MURPHY CATHERINE J; LOHSE SAMUEL E; ELLER JONATHAN R
权利人:UNIV ILLINOIS
摘要:A continuous flow reactor for nanoparticle synthesis comprises a modular system including a plurality of interconnected tubular components for fluid flow therethrough including a first tubular inlet and a second tubular inlet connected to a three-way junction comprising a tubular mixer. A continuous flow method for nanoparticle synthesis comprises flowing a growth solution and a reaction-initiating solution into a mixing portion of a flow reactor to form a mixed solution; flowing the mixed solution through a holding portion of the flow reactor for a predetermined residence time to form a reacted solution comprising nanoparticles; and continuously removing the reacted solution from the flow reactor so as to achieve a throughput of nanoparticles of at least about 0.5 mg/min.

专利号:US-2021379557-A1
优先权日:2018-10-23
标题 :A system and method for promoting chemical reactions
发明人：NAAMAN RON; FONTANESI CLAUDIO; TASSINARI FRANCESCO; MISHRA SURYAKANT; CAPUA EYAL; PALTIEL YOSSEF; YOCHELIS SHIRA; METZGER TZURIEL
权利人:YEDA RES & DEV; YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD
摘要:A system and method for use in synthesis and promoting interactions of chiral molecules. The system can include: a container configured for containing fluid mixture comprising one or more reactant molecules and at least one surface comprising ferromagnetic or paramagnetic material located to be in at least partial contact with reactants in said container. The ferromagnetic of paramagnetic material can be magnetizable with magnetization direction perpendicular to said at least one surface, thereby providing chiral selective synthesis from said one or more reactant molecules. The technique can enable selective interactions of enantiomers of selected handedness of chiral molecules or formation of selected enantiomers from achiral molecule reactants.

专利号:US-11918657-B2
优先权日:2017-11-10
标 题 :Dendrimer delivery system and methods of use thereof
发明人：RANGARAMANUJAM KANNAN; SHARMA RISHI; SHARMA ANJALI; KANNAN SUJATHA; ZHANG ZHI; KAMBHAMPATI SIVA PRAMODH
权利人:UNIV JOHNS HOPKINS
摘要:Low-generation dendrimers containing a high density of surface hydroxyl groups, and methods of synthesis thereof are provided. In particular, oligo ethylene glycol (OEG)-like dendrimers with a high surface functional groups at relatively low generations (e.g. Ëœ120 hydroxyls in the third generation, with a size of just 1-2 nm) is described. Dendrimer formulations including one or more prophylactic, therapeutic, and/or diagnostic agents, and methods of use thereof are also described. The formulations are suitable for topical, enteral, and/or parenteral delivery for treating one or more diseases, conditions, and injuries in the eye, the brain and nervous system (CNS), particularly those associated with pathological activation of microglia and astrocytes.