CAS: 16862-05-8; Methyl 3-(Thiophen-2-yl)Propanoate

该化合物是一种有机化合物,其特征是其酯功能组,该化合物来自一种碳酸和酒精的反应.该化合物的特征是带有甲基酯和硫苯环的丙烯基柱,特别是2-二-二二基基环,有助于其芳香特性.硫磷环的存在具有独特的电子和性能特征,使其对各种化学应用,包括合成和潜在的生物活动感兴趣.甲基-3-(2-2-二乙基)对黄色液一般是色素不至色色色的黄色液体,有香味,表明其在口味和香味工业中的潜在用途.有机溶剂是可溶性,可增强有机合成的效用.与许多有机化合物一样,必须小心处理,遵守安全规程,以减少与使用该环有关的任何风险.其反应和相互作用可能受到功能组的存在的影响,使该物质在有机化学中成为多用途的化合物.

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5928-51-8 19498-72-7 14779-24-9

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合成工艺路线路线简述

    📜3-(2-噻吩)丙酸置于氯化亚砜体系中,化学反应 3.0H,反应生成3-(2-噻吩)丙酸甲酯
    参考文献:Synthesis Of Selective Srpk-1 Inhibitors: Novel Tricyclic Quinoxaline Derivatives
    标题:Synthesis Of Selective Srpk-1 Inhibitors: Novel Tricyclic Quinoxaline Derivatives
    摘要:Sr Protein-Specific Kinase-1 (Srpk-1) Has Been Identified As A Validated Target For Hepatitis B Virus (Hbv). A Series Of Novel Tricyclic Quinoxaline Derivatives Was Designed And Synthesised As Potential Kinase Inhibitory Antiviral Agents And Was Found To Be Active And Selective For Srpk-1 Kinase. Most Of These Novel Compounds Have Drug-Like Properties According To Experimentally Determined Log P And Log S Values. (C) 2005 Elsevier Ltd. All Rights Reserved.
    Doi:10.1016/j.Bmcl.2005.04.064

    海关参考信息

    专利信息


    专利号:US-4563537-A
    优先权日:1982-09-27
    标题:Synthesis of thiophene-containing prostaglandin endoperoxide apparatus
    发明人：LAROCK RICHARD C
    权利人:UNIV IOWA STATE RES FOUND INC
    摘要:New organopalladium reactions involving the addition of thienylpalladium compounds to strained bicyclic alkenes, and subsequent chain extension reactions employing the chemistry of organopalladium compounds are disclosed. By these techniques a large number of bicyclic prostaglandin analogs are prepared, which are useful as inhibitors of arachidonic acid induced blood platelet aggregation, and are specific inhibitors of thromboxane synthetase.

    专利号:US-4520207-A
    优先权日:1982-09-27
    标 题:Synthesis of thiophene-containing prostaglandin endoperoxide analogs
    发明人：LAROCK RICHARD C
    权利人:UNIV IOWA STATE RES FOUND INC
    摘要:New organopalladium reactions involving the addition of thienylpalladium compounds to strained bicyclic alkenes, and subsequent chain extension reactions employing the chemistry of organopalladium compounds are disclosed. By these techniques a large number of bicyclic prostaglandin analogs are prepared, which are useful as inhibitors of arachidonic acid induced blood platelet aggregation, and are specific inhibitors of thromboxane synthetase.

    专利号:RU-2124513-C1
    优先权日:1991-08-14
    标题:(e)-3-[2-n-butyl-1-{(4-carboxyphenyl)-methyl}-1h-imidazole-5- -yl]-2-(2-thienyl)-methyl-2-propenoic acid methanesulfonate, method of its synthesis, pharmaceutical composition based on thereof

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    合成参考文献


    摘要:Harnying, W.; Berkessel, A., Science of Synthesis: Knowledge Updates, (2024) 1, 358.
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