CAS: 16052-06-5; 3-[4-(2-Hydroxyethyl)-1-Piperazinyl]Propanesulfonic Acid

在 乙醇,水体系中,用80 %的收率获得4-羟乙基哌嗪丙磺酸
参考文献:Cn117105883
标题:Cn117105883

专利信息

专利号:US-10501782-B1
优先权日:2014-09-05
标题:Cell-free synthesis of DNA by strand displacement
发明人：PORTER NEIL; ROTHWELL PAUL; EXTANCE JONATHAN
权利人:TOUCHLIGHT IP LTD
摘要:The present invention relates to an improved process for synthesis of DNA, RNA, proteins and like molecules, in particular cell-free enzymatic synthesis of DNA, preferably in large scale. The present invention relates to the synthesis of DNA using strand-displacement replication and the addition of nucleotides to the reaction mixture is controlled, thus controlling yield. The reaction mixture contains a starting amount of nucleotides, polymerase and DNA template, to which further nucleotides are supplied in a controlled manner.

专利号:US-8420848-B2
优先权日:2009-01-09
标题:Process for the synthesis of beta glycerol phosphate
发明人：KULKARNI YASHWANT
权利人:KULKARNI YASHWANT; SIGMA ALDRICH CO LLC
摘要:The present invention provides methods for the preparation of beta glycerol phosphate and its salts. In particular, the invention provides efficient methods for the synthesis of beta glycerol phosphate of high purity.

专利号:US-2025136636-A1
优先权日:2021-08-16
标 题:Nucleotide complexes capable of an improved dna synthesis yield
发明人：KYSH DANIEL; ROTHWELL PAUL
权利人:TOUCHLIGHT IP LTD
摘要:The present invention relates to novel nucleotide complexes which enhance the enzymatic production of DNA. The nucleotide complexes includes a divalent cation at a ratio of 0.2-1.5 divalent cations per nucleotide, whilst monovalent ions (other than hydrogen or hydronium ions from any solvent) are minimal. The nucleotide complexes have desirable properties for the synthesis of deoxyribonucleic acid (DNA), in particular cell-free enzymatic synthesis of DNA, preferably on a large or industrial scale. Further, the invention includes improved processes for preparing said nucleotide complexes. Further complexes are disclosed which possess unique properties in accelerating DNA synthesis at higher concentrations, these complexes also containing zwitterion molecules.

专利号:US-2023091493-A1
优先权日:2020-02-14
标 题:Dna synthesis yield improvements
发明人：ROTHWELL PAUL; KYSH DANIEL; PORTER NEIL
权利人:TOUCHLIGHT IP LTD
摘要:The present invention relates to an improved process for synthesis of deoxyribonucleic acid (DNA), in particular cell-free enzymatic synthesis of DNA, preferably on a large or industrial scale, with an improved yield and/or with an improved efficiency. The invention requires the use of nucleotide complexes wherein the nucleotide is associated with a mixture of divalent and monovalent cations. Preferably, the divalent cation may be magnesium or manganese.

专利号:US-9856251-B2
优先权日:2008-09-03
标题:Substituted berbines and processes for their synthesis
发明人：WANG PETER X; MOSER FRANK W; CANTRELL GARY L; GROTE CHRISTOPHER W
权利人:MALLINCKRODT LLC
摘要:The present invention provides processes for the synthesis of substituted berbine compounds. Also provided are intermediates used in the synthesis of substituted berbine compounds.

专利号:WO-2024153643-A1
优先权日:2023-01-16
标 题 :Inkjet-assisted enzymatic nucleic acid synthesis
发明人：MOGHADDAM NICOLAS; ADELIZZI BEATRICE; LOMAN TESSA; VERARDO DAMIANO; RODRIGUEZ-PINZON DANIEL; HORGAN ADRIAN
权利人:DNA SCRIPT
摘要:Methods, devices, and compositions are provided for inkjet-assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions include printable stabile formulations of synthesis reagents for inkjet delivery including, but not limited to, template-free polymerases, divalent cations, and nucleotides.