CAS: 157355-81-2; (2R,3S)-2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-3-Hydroxybutanoic Acid

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73731-37-0 146306-75-4 130674-54-3

上下游产品

CAS号632-20-2 D-苏氨酸 | CAS号28920-43-6 芴甲氧羰酰氯(Fm°C-Cl) | CAS号82911-69-1 9-芴甲基-N-琥珀酰亚胺碳酸酯

📜D-苏氨酸,9-芴甲基-N-琥珀酰亚胺基碳酸酯置于碳酸氢钠体系中,用 1,4-二氧六环,水 用作溶剂,化学反应生成N-(9-芴甲氧羰基)-D-苏氨酸
参考文献:完全合成脂蛋白,一种有效的细胞凋亡诱导环肽.
标题:完全合成脂蛋白,一种有效的细胞凋亡诱导环肽.
摘要:通过16种操作(32个单独的反应)已实现了胰蛋白酶的双向全合成,并且容易获得的材料的总收率为3%.钯催化的色氨酸合成,非对映选择性硒环化和氧化脱硒成功地成为构建二聚体核心氨基酸的关键步骤.2-溴-1-乙基吡啶鎓四氟硼酸酯被有效地用于肽偶联中,并且在该合成中具有空间限制.
Doi:10.1021/ol100135A

专利信息

专利号:WO-2025094036-A1
优先权日:2023-10-30
标题:A process for the preparation of liraglutide
发明人：TANEJA GAURAV; VISHWAKARMA VIJAYKUMAR; KHANDVE PRANAV; JOGADE SAMEER; KESARKAR PRAJAKTA
权利人:PIRAMAL PHARMA LTD
摘要:The present invention relates to a process for preparing Liraglutide by solid phase peptide synthesis (SPPS). It describes a convergent synthesis by using different fragments including pseudoprolines in one or more of the fragments bound to a solid support.

专利号:US-2025011366-A1
优先权日:2021-09-08
标 题:Prodrugs of Antibiotic Teixobactin
发明人：JONES CHELSEA R; NOWICK JAMES S
权利人:UNIV CALIFORNIA
摘要:Prodrugs of antibiotic teixobactin, methods of their synthesis, and methods of their use as antimicrobial treatments are described. The teixobactin prodrugs incorporate one or more O-acyl linkages. The O-acyl linkages can be utilized in substitution of amide peptide bonds between an amino acid containing an alcohol side chain and the immediately preceding amino acid.

专利号:CN-118359700-A
优先权日:2024-04-11
标题 :Method for assisting in synthesis of TrkA-related D-type protein by using glycosylation modification

专利号:US-11897970-B2
优先权日:2017-03-09
标 题 :Antibacterial products
发明人：SINGH ISHWAR; TAYLOR EDWARD
权利人:UNIV LIVERPOOL
摘要:The invention provides novel antibacterial compounds of formulae IA, IB and IC as defined herein. Optionally, the antibacterial compounds can be bonded to a delivery agent that is capable of bonding to one or more structures on a bacterial cell membrane. The invention also provides the use of such compounds in treating or preventing bacterial infections, and processes for their synthesis.