CAS: 1424-00-6; Mesterolone

上下游产品

17β-hydroxy-1-methyl-5α-androst-1-en-3-one 17β-hydroxy-1α-methyl-androst-4-en-3-one 5α-androst-1-en-3-one-17β-yl benzoate methylmagnesium bromide1α-Methyl-5α-androstan-3α,17β-diol 17β-hydroxy-1α-methyl-androst-4-en-3-one 1α,17α-Dimethyl-17β-hydroxy-5α-androstan-3-on

📜17Beta-羟基-1Alpha-甲基雄甾-4-烯-3-酮置于氨,Lithium,4-甲基-3戊烯-2-酮体系中,用 四氢呋喃,叔丁醇 用作溶剂,以98%的收率获得甲氢睾酮
参考文献:Use Of Alpha,Beta-Unsaturated Carbonyl Compounds As Quench Reagents For The Birch Reduction
标题:Use Of Alpha,Beta-Unsaturated Carbonyl Compounds As Quench Reagents For The Birch Reduction
摘要:α,β-不饱和羰基化合物作为birch还原的淬灭试剂的应用.

专利信息

专利号:US-5908944-A
优先权日:1991-09-27
标题 :Methylation or ethylation agent and process for 1,4-addition of a methyl or ethyl group to an α, β-unsaturated keto compound
发明人：WESTERMANN JUERGEN; NICKISCH KLAUS
权利人:SCHERING AG
摘要:This invention describes a new methylation or ethylation agent containing trimethyl aluminum or dimethyl zinc or triethyl aluminum as methyl or ethyl source, which additionally contains catalytic amounts of one or more copper(I) and/or copper(II) compounds as well as a process for the 1,4-addition of a methyl or ethyl group to an α,β-unsaturated or an α,β-double unsaturated ketone or an α,β-unsaturated aldehyde using the agent according to the invention. n By using only catalytic amounts of copper and a CKW (chlorinatedhydrocarbon)-free reaction medium, the new methylation/ethylation agent/process is distinguished by its environmental compatibility and it is, for example, suitable for the production of initial products for the synthesis of biologically effective compounds.

专利号:US-2013035307-A1
优先权日:2010-01-26
标 题:Methods for treating or preventing the spread of cancer using semi-synthetic glycosaminoglycosan ethers
发明人：PRESTWICH GLENN D; KENNEDY THOMAS P
权利人:UNIV UTAH RES FOUND; PRESTWICH GLENN D; KENNEDY THOMAS P
摘要:Described herein are methods for the treatment and prevention of tumor metastasis using alkylated and fluoroalkylated semi-synthetic glycosaminoglycan ethers (“SAGEsâ€?). The synthesis of sulfated alkylated and fluoroalkylated SAGEs is also described.

专利号:US-9180171-B2
优先权日:2011-01-25
标题 :Method of regulating fertilizing ability using cyclic ADP-ribose and CD38
发明人：KIM UH-HYUN; PARK KWANG-HYUN; KIM BYUNG-JU
权利人:NAT UNIV CHONBUK IND COOP FOUND
摘要:The present invention relates to a pharmaceutical composition for promoting fertilization comprising cyclic ADP-ribose or its derivative, CD38 and to a method of promoting fertilization by promoting the synthesis of cyclic ADP-ribose to increase sperm motility. Also, the present invention relates to a pharmaceutical composition for contraception and a method for inhibiting fertilization, which can inhibit the expression or function of cyclic ADP-ribose to reduce sperm motility, thereby inhibiting fertilization.

专利号:US-11732090-B2
优先权日:2016-12-21
标 题:Poly(ether ketone ketone) polymers, corresponding synthesis methods and polymer compositions and articles made therefrom
发明人：LOUIS CHANTAL
权利人:SOLVAY SPECIALTY POLYMERS USA
摘要:Described herein are PEKK polymers having improved processability and improved crystallinity. It was surprisingly found that PEKK polymers formed using a specifically adapted nucleophilic synthesis route, in which different monomers are added in to the polymerization reaction at different points during the synthesis, had lower glass transition temperatures (“Tgâ€?) and increased crystallinities, relative to PEKK polymers formed using traditional nucleophilic synthesis routes (“traditional PEKK polymersâ€?). Furthermore, compared with PEKK polymers synthesized using an electrophilic synthesis routes, the PEKK polymers described herein and significantly lower halogen content. The synthesis routes includes a first heating of a first monomer blend in a reaction mixture, a subsequent first addition of a second monomer blend to the reaction mixture, and a second heating of the reaction mixture subsequent to the first addition.

专利号:WO-2018115033-A1
优先权日:2016-12-21
标题:Poly(ether ketone ketone) polymers, corresponding synthesis methods and polymer compositions and articles made therefrom
发明人：LOUIS CHANTAL
权利人:SOLVAY SPECIALTY POLYMERS USA
摘要:Described herein are PEKK polymers having improved processability and improved crystallinity. It was surprisingly found that PEKK polymers formed using a specifically adapted nucleophilic synthesis route, in which different monomers are added to the polymerization reaction at different points during the synthesis, had lower glass transition temperatures ('Tg') and increased crystallinities, relative to PEKK polymers formed using traditional nucleophilic synthesis routes ('traditional PEKK polymers'). Furthermore, compared with PEKK polymers synthesized using an electrophilic synthesis routes, the PEKK polymers described herein and significantly lower halogen content. The synthesis routes includes a first heating of a first monomer blend in a reaction mixture, a subsequent first addition of a second monomer blend to the reaction mixture, and a second heating of the reaction mixture subsequent to the first addition.

专利号:US-12202940-B2
优先权日:2016-12-21
标题:Poly (ether ketone ketone) polymers, corresponding synthesis methods and polymer compositions and articles made therefrom
发明人：LOUIS CHANTAL
权利人:SOLVAY SPECIALTY POLYMERS USA
摘要:Described herein are poly(ether ketone ketone) (“PEKKâ€?) polymers having improved processability. It was surprisingly discovered that by selectively controlling the relative amounts of reactants during the synthesis, PEKK polymers having unexpectedly lower melt viscosities can be obtained. More particularly, by selectively controlling the relative amounts of monomers used to form recurring units of the PEKK polymer, in conjunction with selective control of other reaction components, the resulting PEKK polymers had reduced viscosities, relative to PEKK polymers synthesized by using tradition reaction schemes (“traditional PEKK polymersâ€?). By providing PEKK polymers with lower melt viscosities, the PEKK polymers described herein have improved processability.