CAS: 13296-94-1; 2-Bromo-4-Nitroaniline

该化合物是一种卤化硝酸盐化合物,其分子式为C6H5BRN2O2.它是一个有机合成的多用途中间体,特别是在染料,药品和农用化学物的制作方面.在阴性环上存在溴和硝基替代物,可以增强其反应性,在交叉反应和核生殖替代中实现选择性功能化.其晶体固态在标准条件下确保稳定性,便利处理和储存.该化合物的清晰结构和高纯度使其适合在研究和工业工艺中精确应用.其在合成复杂的芳性衍生物中的效用强调了其在精细的化学制造中的重要性.

结构式图片

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合成工艺路线路线简述

    1,2-二溴-4-硝基苯置于乙醇,氨体系中,化学反应生成2-溴-4-硝基苯胺
    参考文献:Koerner,Gazzetta Chimica Italiana,1874,Vol. 4,P. 341
    标题:Koerner,Gazzetta Chimica Italiana,1874,Vol. 4,P. 341

    专利信息


    专利号:CN-114181089-A
    优先权日:2021-12-20
    标题:A kind of method for continuous synthesis of p-nitroaniline

    专利号:US-11149034-B2
    优先权日:2017-07-25
    标 题:Derivatives of luciferin and methods for their synthesis
    发明人:JARDINE MOEGAMAT ANWAR; RYLANDS MARWAAN
    权利人:UNIV CAPE TOWN
    摘要:6-Thio derivatives of D-luciferin, also referred to as D-thioluciferins, having the general structure of Formula (I) are provided. Methods for synthesising D-luciferin, its derivatives, and their related 2-cyanobenzothiazole precursors are also provided. These compounds are commercially valuable due to their application in optical imaging, particularly in bioluminescence imaging.

    专利号:US-4136033-A
    优先权日:1969-11-07
    标 题:6-hydroxypyridone-2 compounds having a cationic group in the 3-position
    发明人:STEINEMANN WILLY
    权利人:SANDOZ LTD
    摘要:Compounds of the formula ##STR1## wherein K.sup.⊕ is a cationic group, preferably heterocyclic, n R is hydrogen or an organic radical, preferably alkyl, phenyl or acyl, n R 1 is hydrogen, hydrocarbyl, substituted hydrocarbyl, heterocyclyl, substituted heterocyclyl, amino or substituted amino, and n A.sup.⊖ is an anion, n Are useful as intermediates in the synthesis of azo dyes of the formula ##STR2## wherein D is an aromatic carbocyclic or heterocyclic diazo component radical, and n K.sup.⊕, r, r 1 and A.sup.⊖ are as defined above.

    专利号:US-5776984-A
    优先权日:1996-11-08
    标题:Prostaglandin synthase-2 inhibitors
    发明人:DELLARIA JOSEPH F; GANE TODD H
    权利人:ABBOTT LAB
    摘要:The present invention provides a compound of the formula: Such compounds are useful for inhibiting prostaglandin synthesis. Pharmaceutical compositions and methods for inhibiting prostaglandin synthesis are also disclosed.

    专利号:WO-2019021202-A1
    优先权日:2017-07-25
    标题:LUCIFERIN DERIVATIVES AND METHODS OF SYNTHESIS

    专利号:EP-3658544-B1
    优先权日:2017-07-25
    标 题 :Derivatives of luciferin and methods for their synthesis
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    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 108.
    摘要:Irudayanathan, F. M.; Lee, S., Science of Synthesis Knowledge Updates, (2019) 2, 34.
    摘要:Stanforth, S. P., Science of Synthesis Knowledge Updates, (2015) 1, 212.
    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#03288
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