CAS: 112776-83-7; Diethyl 4-Bromopyridine-2,6-Dicarboxylate

相似化合物

120491-88-5 162102-81-0 128184-01-0

上下游产品

CAS号499-51-4 4-羟基吡啶-2,6-二甲酸 | CAS号64-17-5 乙醇 | CAS号138-60-3 白屈氨酸 | CAS号120491-93-2 4-bromopyridine... | CAS号162102-81-0 4-溴-2,6-吡啶二羧酸 一水合物 | CAS号99-32-1 白屈菜酸 | CAS号68854-18-2 三氧代庚二酸二乙酯 | CAS号206647-42-9 4-bromopyridine... | CAS号329974-08-5 4-bromopyridine... | CAS号329974-10-9 4-bromopyridine... | CAS号15658-60-3 2,6-吡啶二羧酸二乙酯 | CAS号162102-81-0 4-溴-2,6-吡啶二羧酸 一水合物 | CAS号120491-88-5 (4-溴吡啶-2,6-二基)二甲醇 | CAS号112776-86-0 diethyl 4-(2-ph... | CAS号197712-58-6 diethyl 4-methy... | CAS号506423-80-9 4-吲哚吡啶-2,6-二羧酸

📜4-羟基-2,6-吡啶二羧酸二乙酯置于五溴化磷体系中,用 乙醇 用作溶剂,以86%的收率获得4-溴吡啶-2,6-二羧酸二乙酯
参考文献:结合有膦酸酯基的基于聚恶唑的大环的设计与合成
标题:结合有膦酸酯基的基于聚恶唑的大环的设计与合成
摘要:我们介绍了含有膦酸酯基团的基于聚恶唑的大环化合物的设计和合成.建立了可靠的途径,该途径允许在大环周边方便且通用地引入各种膦酸酯官能团,例如膦酸酯,酸和盐.预计这种前所未有的大环化合物将成为端粒酶抑制剂的诱人候选物.
Doi:10.1002/cjoc.201400213

专利信息

专利号:WO-9943409-A1
优先权日:1998-02-27
标 题:Hplc fractionation of complex chemical mixtures
发明人：COOK PHILLIP DAN; CUMMINS LENDELL L; GRIFFEY RICHARD H; KAWASAKI ANDREW M; GAUS HANS; AN HAOYUN
权利人:ISIS PHARMACEUTICALS INC; COOK PHILLIP DAN; CUMMINS LENDELL L; GRIFFEY RICHARD H; KAWASAKI ANDREW M; GAUS HANS; AN HAOYUN
摘要:The rapid deconvolution of complex chemical mixtures, such as combinatorial libraries prepared via solution-phase simultaneous addition of functionalities is demonstrated using HPLC. Libraries containing 25-216 members were screened for biological activity and active libraries are fractionated into discreet pools using preferred reversed-phase HPLC. The entire process can be completed from a single synthesis of 15-50 mg, without the need for fixed positions, serial synthesis, or tagging.

专利号:US-8221719-B2
优先权日:2007-09-05
标 题:Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof
发明人：PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI
权利人:PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI; WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.

专利号:US-8143057-B2
优先权日:2003-12-18
标题 :Chelating agents and highly luminescent and stable chelates and their use
发明人：HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI
权利人:HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI; WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.

专利号:US-8071626-B2
优先权日:2003-12-18
标 题 :Chelating agents and highly luminescent and stable chelates and their use
发明人：HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI
权利人:HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI; WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.

专利号:EP-1658282-B1
优先权日:2003-08-29
标题:Novel chelating agents and chelates and their use
发明人：HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI
权利人:WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.