CAS: 111-35-3; 3-Ethoxypropan-1-Ol

上下游产品

CAS号626-68-6 2-Methyl-1,3-dioxane | CAS号2806-85-1 Propanal, 3-ethoxy | CAS号763-69-9 3-乙氧基丙酸乙酯 | CAS号86852-11-1 Diethyloxytriph... | CAS号504-63-2 1,3-丙二醇 | CAS号74-96-4 溴乙烷 | CAS号1589-49-7 3-甲氧基-1-丙醇 | CAS号7789-92-6 1,1,3-三乙氧基丙烷 | CAS号503-30-0 三甲氧基酯 | CAS号71-23-8 正丙醇 | CAS号64-17-5 乙醇 | CAS号107-21-1 乙二醇 | CAS号75-07-0 乙醛 | CAS号64-19-7 冰醋酸 | CAS号123-38-6 丙醛 | CAS号298-12-4 乙醛酸 | CAS号503-66-2 3-羟基丙酸 | CAS号504-63-2 1,3-丙二醇

3-乙氧基丙醛置于氢气体系中,化学反应生成1,3-丙二醇单乙醚
参考文献:四齿膦配体及其制备方法,氢甲酰化的催化剂及反应方法,1,3-丙二醇的制备方法
标题:四齿膦配体及其制备方法,氢甲酰化的催化剂及反应方法,1,3-丙二醇的制备方法
摘要:本申请提供一种四齿膦配体及其制备方法,氢甲酰化的催化剂及反应方法,1,3‑丙二醇的制备方法,属于化合物材料技术领域.四齿膦配体的通式如下:式中,R1为氢或卤素;R2为含氮的杂环或该四齿膦配体与铑络合物配合,可以用来进行氢甲酰化催化反应,可进行1,3‑丙二醇的制备.

专利信息

专利号:US-8198465-B2
优先权日:2005-10-17
标 题 :3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
发明人：SEDELMEIER GOTTFRIED; GRIMLER DOMINIQUE; ACEMOGLU MURAT
权利人:SEDELMEIER GOTTFRIED; GRIMLER DOMINIQUE; ACEMOGLU MURAT; NOVARTIS AG
摘要:The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula II, n nor a salt thereof, and a compound of formula VIn n nor a salt thereof, wherein R 3 and R 4 as well as Act are as defined in the specification, and processes of manufacturing these.n n Additionally transformation of compounds (VI) with metallo organic compounds (VII) give rise to the new compounds (VIII) which are direct precursors for the preparation of Aliskiren.

专利号:WO-9529150-A1
优先权日:1994-04-21
标 题 :Synthesis of prototypes for renin inhibitors
发明人：HANESSIAN STEPHEN
权利人:CIBA GEIGY AG; HANESSIAN STEPHEN
摘要:Prototype renin inhibitors having general structure (I), where n is 0-3 inclusive, A are either both hydrogen atoms or together are a single carbon-nitrogen bond, R1 is hydrogen, or hydrocarbylcarboxy wherein the hydrocarbyl entity is selected from the group consisting of alkyl of 1 to 6 carbon atoms or aralkyl of 7 to 10 carbon atoms, R2 and R3 or independently alkyl of 1 to 4 carbon atoms, R4 is alkyl of 1 to 6 carbon atoms or a substituent of aliphatic character such as, for example, butyl, 2-morpholinoethyl or 2-carbamoyl-2-methyl-propyl, R5 is selected from aromatics, substitued aromatics and heteroaromatics, substituted or unsubstituted cycloalkyls, cycloalkenes having 3 to 8 carbon atoms, with substituents selected from alkyl, alkoxy of 3 to 10 carbon atoms and alkoxy derivatives such as 3-methoxy-propyloxy, primary and secondary amides, alkyl derivatives, are prepared by novel multistep synthesis. Such compounds are valuable intermediates for the manufacture of pharmaceutical such as Renin inhibitors and HIV-protease inhibitors.

专利号:US-2009088576-A1
优先权日:2006-01-30
标题:Process for the Stereoselective Preparation of Alcohols From Alpha, Beta-Insaturated Compounds
发明人：HEROLD PETER; STUTZ STEFAN; MAH ROBERT; STOJANOVIC ALEKSANDAR; LYOTHIER ISABELLE; BEHNKE DIRK; SPINDLER FELIX; BAPPERT ERHARD
权利人:HEROLD PETER; STUTZ STEFAN; MAH ROBERT; STOJANOVIC ALEKSANDAR; LYOTHIER ISABELLE; BEHNKE DIRK; SPINDLER FELIX; BAPPERT ERHARD
摘要:A process for the synthesis of an alcohol of formula (I), using as intermediate a compound of formula (V).

专利号:US-4161609-A
优先权日:1977-09-14
标题:Synthesis of carboxylic acid esters
发明人：CRAMER RICHARD D
权利人:DU PONT
摘要:A method is provided for converting a carboxylic acid amide to a carboxylic acid ester by reacting a vaporized mixture of the amide and an aliphatic alcohol or a phenol in the presence of a suitable catalyst at temperatures of from 100 DEG C. to 400 DEG C. The process is especially useful for the conversion of methacrylamide to methyl methacrylate.

专利号:WO-0078725-A1
优先权日:1999-06-18
标题 :Synthesis of substituted amidines
发明人：CHOUEIRY DANIELE; GIRAUD DANIEL LIONEL; SCHOTTEN THEO
权利人:LILLY CO ELI; CHOUEIRY DANIELE; GIRAUD DANIEL LIONEL; SCHOTTEN THEO
摘要:The present invention provides a process for preparing amidines starting from carboxylic acid derivatives, in which the carboxylic acid containing moiety is attached to a sp3-, or sp 2- or sp1¿-hybridized carbon atom. The sp2-hybridized carbon atom, to which the carboxylic acid containing moiety is attached to may be part of an aromatic or heteroaromatic or olefinic system.

专利号:US-8143416-B2
优先权日:2004-08-31
标题 :Alternative synthesis of renin inhibitors and intermediates thereof
发明人：SEDELMEIER GOTTFRIED; MICKEL STUART JOHN; RUEEGER HEINRICH
权利人:SEDELMEIER GOTTFRIED; MICKEL STUART JOHN; RUEEGER HEINRICH; NOVARTIS AG
摘要:The present invention relates to synthetic routes to prepare a compound of the formula n nwherein R 1 is halogen, C 1-6 halogenalkyl, C 1-6 alkoxy-C 1-6 alkyloxy or C 1-6 alkoxy-C 1-6 alkyl; R 2 is halogen, C 1-4 alkyl or C 1-4 alkoxy; R 3 and R 4 are independently branched C 3-6 alkyl; and R 5 is cycloalkyl, C 1-6 alkyl, C 1-6 hydroxyalkyl, C 1-6 alkoxy-C 1-6 alkyl, C 1-6 alkanoyloxy-C 1-6 alkyl, C 1-6 aminoalkyl, C 1-6 alkylamino-C 1-6 alkyl, C 1-6 dialkylamino-C 1-6 alkyl, C 1-6 alkanoylamino-C 1-6 alkyl, HO(O)C—C 1-6 alkyl, C 1-6 alkyl-O—(O)C—C 1-6 alkyl, H 2 N—C(O)—C 1-6 alkyl, C 1-6 alkyl-HN—C(O)—C 1-6 alkyl or (C 1-6 alkyl) 2 N—C(O)—C 1-6 alkyl; or a pharmaceutically acceptable salt thereof as well as key intermediates obtained when following these routes as well as their preparation.