CAS: 66612-29-1; N-(4-Aminobutyl)-N-Ethylisoluminol

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CAS号73819-87-1 5-((4-(1,3-二氧代异... | CAS号66612-32-6 N-(6-氨基己基)-N-乙基异鲁米诺

4-{n-Ethyl-N-[4-(N-Phthalimido)Butyl]Amino}-N-Methylphthalimide置于肼体系中,用 乙醇 作为反应溶剂,化学反应 4.0H,反应生成 N-(4-氨丁基)-N-乙基异鲁米诺
参考文献:Microenvironmental Effects Of Water-Soluble Polymers On The Chemiluminescence Of Luminol And Its Analogs
标题:Microenvironmental Effects Of Water-Soluble Polymers On The Chemiluminescence Of Luminol And Its Analogs
摘要:水溶性聚合物(wsps),如牛血清白蛋白(bsa)和聚乙烯亚胺(pei),对水溶液中化学发光(cl)的影响已被研究.这些wsps浓度的增加强烈增强了cl发射,特别是在cl反应的初始阶段.这归因于在发光物种形成之前的化学反应加速.bsa的特殊之处在于,它可以在中性ph条件下增强cl.据推测,这些wsps提供了适合cl反应的疏水和碱性微环境.
DOI:10.1246/bcsj.60.2023

专利信息

专利号:US-5817786-A
优先权日:1983-02-22
标题 :Single-stranded labelled oligonucleotides of preselected sequences
发明人：RUTH JERRY L
权利人:MOLECULAR BIOSYSTEMS INC
摘要:Substantially pure single-stranded oligonucleotides having a preselected sequence of not more than about 200 nucleotides, at least one of which is at a preselected position in the sequence and includes a base with a covalently attached linker arm containing or capable of binding at least one reporter group or solid support. A process for the chemical synthesis of the substantially pure single-stranded oligonucleotide and modified nucleosides useful in such synthesis are provided.

专利号:US-8652442-B2
优先权日:2008-11-03
标题 :Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor
发明人：PIWNICA-WORMS DAVID; GROSS SHIMON; SHARMA VIJAY; GAMMON SETH
权利人:PIWNICA-WORMS DAVID; GROSS SHIMON; SHARMA VIJAY; GAMMON SETH; UNIV WASHINGTON
摘要:Methods of imaging distribution of myeloperoxidase activity in a subject are disclosed. These methods include the use of bioluminescent substrates, including luminol and wavelength-shifted analogues of luminol. Bioluminescent myeloperoxidase substrates that emit light at longer wavelengths compared to luminol are shown to be useful for imaging myeloperoxidase activity in vivo. The disclosed methods can be used for imaging sites of inflammation and other pathological conditions associated with abnormal levels of MPO activity in vivo. Methods of synthesis of luminol analogues are also disclosed.

专利号:US-4226993-A
优先权日:1978-07-24
标题:Amino-functionalized phthalhydrazides
发明人：BUCKLER ROBERT T; SCHROEDER HARTMUT R
权利人:MILES LAB
摘要:Amino-functionalized phthalhydrazides of the formula: ##STR1## wherein one of R 5 and R 6 is hydrogen and the other is --NR 7 R 8 ; R 7 is hydrogen or straight chain alkyl containing 1-4 carbon atoms and R 8 is n n H.sub.2 N--CH.sub.2).sub.n n n wherein n=2-8. The compounds are intermediates in the synthesis of chemiluminescent phthalhydrazide-labeled conjugates which are useful as reagents in specific binding assays for determining ligands or their specific binding partners in liquid media.

专利号:US-4212805-A
优先权日:1978-07-24
标 题:Bis-phthalimides
发明人：BUCKLER ROBERT T; SCHROEDER HARTMUT R
权利人:MILES LAB
摘要:Bis-phthalimides of the formula: wherein one of R9 and R10 is hydrogen and the other is-NR11R12; R11 is hydrogen or straight chain alkyl containing 1-4 carbon atoms and R12 is wherein n=2-8. The compounds are intermediates in the synthesis of chemiluminescent phthalhydrazide-labeled conjugates which are useful as reagents in specific binding assays for determining ligands or their specific binding partners in liquid media.

专利号:US-5783699-A
优先权日:1986-10-22
标 题:Chemiluminescent acridinium salts
发明人：MATTINGLY PHILLIP GREGORY; BENNETT LARRY GENE
权利人:ABBOTT LAB
摘要:Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a sulfonamide and acylating with an activated carboxylic acid of an acridine or isomer thereof. The N-sulfonyl-9-acridinium carboxamide and isomers may be conjugated to antigens, haptens, antibodies, and nucleic acids for use in chemiluminescent assays.

专利号:US-5668266-A
优先权日:1983-02-22
标 题 :Synthesis of single-stranded labelled oligonucleotides of preselected sequence