CAS: 60323-98-0; 2-Bromo-5-Methyl-4-Nitropyridine 1-Oxide
该化合物是一种环环有机化合物,其特点是以环状环状环状代替溴原子,一个甲基组和一个硝基化合物,以及一个氧化物功能组.该化合物通常具有与芳香化合物和硝基化合物相关的特性,例如在某些条件下的稳定性和再活性.硝基化合物的存在常常加强其电子哲学特性,使其在各种化学反应中有用,包括核分裂替代.此外,溴替代成分在合成应用中也可以作为遗留的组.该化合物还可能呈现出由于硝基和氧化物组而形成的极地特性,影响其在极溶剂中的溶性.其应用范围可能包括作为有机合成的中间体,到制药或农业化学中的潜在作用,视其耐用性和功能特性而定.应当参考安全数据来处理,因为硝基化合物可能对健康造成风险.
- 英文名称2-Bromo-5-Methyl-4-Nitropyridine 1-Oxide
- 中文名称吡啶,2-溴-5-甲基-4-硝基-1-氧化物
- IUPAC名称2-bromo-5-methyl-4-nitropyridine 1-oxide
- 其它别名2-溴-5-甲基-4-硝基吡啶 1-氧化物; 2-Chloro-5-Methyl-4-Nitropyridine-N-Oxide
- CAS编号60323-98-0
- MFCD编号:MFCD00234157
- EINECS号:821-912-2
- 分子式:C6H5BrN2O3分子量:233.02
- 产品CID: 1579718
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
相似化合物
1074-98-2 14248-66-9 60323-96-8MSDS等安全信息
欧盟法规
C&L通报上下游产品
2-Bromo-5-methylpyridine 2-Bromo-5-methylpyridine N-oxide N-(2-(2,5-difluorophenyl)-5-methylpyridin-4-yl)-1H-pyrazolo[4,3-b]pyridin-7-amine 2-(2,5-difluorophenyl)-5-methylpyridin-4-amine N-(2-(2,5-difluorophenyl)-5-methylpyridin-4-yl)-1-(4-methoxybenzyl)-1H-pyrazolo[4,3-b]pyridin-7-amine N-(2-(2,5-difluorophenyl)-5-methylpyridin-4-yl)-2-(4-methoxybenzyl)-2H-pyrazolo[4,3-b]pyridin-7-amine合成工艺路线路线简述
- 合成目标产物 2-Bromo-5-Methyl-4-Nitropyridine 1-Oxide 主要起始原料 2-Bromo-5-Methylpyridine-1-Oxide
- (文献来源)合成步骤主要原料 2-Bromo-5-Methylpyridine-1-O×ide
📜2-溴-5-甲基吡啶置于硫酸,硝酸,间氯过氧苯甲酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.0H,反应生成 2-溴-5-甲基-4-硝基吡啶 1-氧化物
参考文献:具有有效抗癌活性的秋水仙碱结合位点抑制剂 1H-吡咯并[3,2-C]吡啶衍生物的设计,合成和生物评价
标题:具有有效抗癌活性的秋水仙碱结合位点抑制剂 1H-吡咯并[3,2-C]吡啶衍生物的设计,合成和生物评价
摘要:设计并合成了一系列新的1H-吡咯并[3,2-C]吡啶衍生物作为秋水仙碱结合位点抑制剂.初步生物学评价表明,大多数目标化合物...
DOI:10.1080/14756366.2024.2302320
海关参考信息
- 2933310010-吡啶
2904209090-其他仅含硝基或亚硝基衍生物
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2024400552-A1
优先权日:2016-11-11
标题 :Heterocyclic modulators of lipid synthesis
发明人：BUCKLEY DOUGLAS I; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by dysregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
专利号:US-11622968-B2
优先权日:2011-03-08
标 题:Heterocyclic modulators of lipid synthesis
发明人：BUCKLEY DOUGLAS; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
专利号:US-11034690-B2
优先权日:2016-11-11
标 题:Heterocyclic modulators of lipid synthesis
发明人：BUCKLEY DOUGLAS I; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC; SAGINIET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
专利号:US-9809591-B2
优先权日:2011-03-08
标题 :Heterocyclic modulators of lipid synthesis
发明人：OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W
权利人:3-V BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
专利号:US-2019308969-A1
优先权日:2016-11-11
标 题 :Heterocyclic modulators of lipid synthesis
专利号:US-2022296605-A1
优先权日:2011-03-08
标 题 :Heterocyclic modulators of lipid synthesis
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/bf02315180
摘要:Puszko A. Electronic spectra and structure of 2-bromopicolines, their N-oxides, and 2-bromo-4-nitropicoline N-oxides. Chemistry of Heterocyclic Compounds. 1998 Feb;34(2):174–82. doi: 10.1007/bf02315180.
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