CAS: 602267-26-5; 1-(2-Isocyanoethyl)-4-Pyridin-2-Ylpiperazine
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专利信息
专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
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参考标题:Bi-Functional Complexes And Methods For Making And Using Such Complexes摘要:The Present Invention Is Directed To A Method For The Synthesis Of A Bi-Functional Complex Comprising A Molecule Part And An Identifier Oligonucleotide Part Identifying The Molecule Part. A Part Of The Synthesis Method According To The Present Invention Is Preferably Conducted In One Or More Organic Solvents When A Nascent Bi-Functional Complex Comprising An Optionally Protected Tag Or Oligonucleotide Identifier Is Linked To A Solid Support, And Another Part Of The Synthesis Method Is Preferably Conducted Under Conditions Suitable For Enzymatic Addition Of An Oligonucleotide Tag To A Nascent Bi-Functional Complex In Solution.
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