- 英文名称Pyridine-2,3,4-Triamine
- 中文名称2,3,4-三氨基吡啶
- IUPAC名称pyridine-2,3,4-triamine
- 其它别名2,3,4-三氨基吡啶; 2,3,4-三氨基吡啶 1G; 2,3,4-Triaminopyridine
- CAS编号52559-11-2
- MFCD编号:MFCD09834976
- 分子式:C5H8N4
- 分子量:124.14
- 产品CID: 2512868
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
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CAS号24501-21-1 3-硝基吡啶-2,4-二胺 | CAS号626-03-9 2,4-二羟基吡啶 | CAS号5466-62-6 4,6-二羟基烟酸 | CAS号6975-44-6 4,6-二羟基烟酸乙酯 | CAS号89282-12-2 2,4-二羟基-3-硝基吡啶 | CAS号5975-12-2 2,4-二氯-3-硝基吡啶 | CAS号685542-71-6 3-Pyridinecarbo... | CAS号6317-97-1 4,6-二羟基-5-硝基吡啶-...4,6-二羟基烟酸乙酯置于sodium Sulfide,Sodium Hydroxide,氨,水,硝酸,溶剂黄146,三氯氧磷体系中,化学反应生成 2,3,4-三氨基吡啶
参考文献:Koegl Et Al.,Recueil Des Travaux Chimiques Des Pays-Bas,1948,Vol. 67,P. 29,37
标题:Koegl Et Al.,Recueil Des Travaux Chimiques Des Pays-Bas,1948,Vol. 67,P. 29,37
专利信息
专利号:US-8551996-B2
优先权日:2009-02-20
标题 :Compounds, compositions, methods of synthesis, and methods of treatment
发明人:STEHOUWER JEFF; GOODMAN MARK; KILTS CLINT; NEMEROFF CHARLES
权利人:STEHOUWER JEFF; GOODMAN MARK; KILTS CLINT; NEMEROFF CHARLES; UNIV EMORY
摘要:Briefly described, embodiments of this disclosure include compounds as described herein, labeled compounds as described herein, pharmaceutical composition including compounds described herein, methods of imaging, method of forming a compound as described herein, and the like. In particular, embodiments of the disclosure include a series of triamino-pyridine derivatives and labeled triamino-pyridine derivatives, methods of synthesizing these compounds, intermediate compounds, methods of treatment using these compounds, methods of imaging, diagnosing, localizing, monitoring, and/or assessing a condition (e.g., corticotropin releasing factor type-1 (CRF1)) and/or related biological events, using triamino-pyridine derivatives, and the like. In addition, the present disclosure includes compositions (e.g., labeled triamino-pyridine derivatives that are ligands for the CRF1 receptor) used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging or SPECT imaging).
专利号:US-7615634-B2
优先权日:2003-02-10
标题:4-aminopyrimidine-5-one derivatives
发明人:BARTKOVITZ DAVID JOSEPH; CHU XIN-JIE; DING QINGJIE; JIANG NAN; LOVEY ALLEN JOHN; MOLITERNI JOHN ANTHONY; MULLIN JR JOHN GUILFOYLE; VU BINH THANH; WOVKULICH PETER MICHAEL
权利人:HOFFMANN LA ROCHE
摘要:Novel intermediate compounds are disclosed. These compounds are useful in the synthesis of 4-aminopyrimidine-5-one derivatives that inhibit cyclin-dependent kinases, in particular cyclin-dependent kinase 4 (Cdk4). The 4-aminopyrimidine-5-one derivatives and their pharmaceutically acceptable salts have antiproliferative activity and are useful in the treatment or control of cancer, in particular solid tumors.
专利号:US-2011305636-A1
优先权日:2009-02-20
标题 :Compounds, compositions, methods of synthesis, and methods of treatment
专利号:CA-2482705-A1
优先权日:2002-04-17
标题:Use of meglumine for inhibiting 3-deoxyglucosone synthesis in the skin
专利号:US-2014179919-A1
优先权日:2009-02-20
标 题 :Compounds, compositions, methods of synthesis, and methods of treatment
专利号:WO-2010096426-A8
优先权日:2009-02-20
标题 :Compounds, compositions, methods of synthesis, and methods of treatment