CAS: 2324-98-3; 2,3,5,6-Tetrafluoroanisole

上下游产品

Pentafluorobenzene methanol potassium methanolate sodium methylate 4-methoxy-2,3,5,6-tetrafluoronitrobenzene 2,3,5,6-tetrafluoro-4-methoxybenzaldehyde 1,2,4,5-tetrafluorobenzene-3-iodo-6-methoxybenzene 2,3,5,6-tetraflourophenol

📜2,3,4,5,6-五氟回香醚置于苯硅烷,1,3-Di-Tert-Butyl-2,3-Dihydro-1H-1,3,2-Diazaphosphole体系中,用 乙腈 用作溶剂,化学反应 12.0H,以53%的收率获得2,3,5,6-四氟茴香醚
参考文献:二氮杂磷烯催化的多氟芳烃与苯基硅烷通过协同亲核芳烃取代加氢脱氟
标题:二氮杂磷烯催化的多氟芳烃与苯基硅烷通过协同亲核芳烃取代加氢脱氟
摘要:以二氮杂磷烯为催化剂,苯基硅烷为末端还原剂,实现了多氟芳烃的无金属催化 C-F 键活化.密度泛函理论计算表明了协调的亲核芳族取代机制.
Doi:10.1021/acs.Joc.1C02360

专利信息

专利号:US-2020047146-A1
优先权日:2017-03-17
标 题 :Hydroxyalkylated polyacrylamide surface coatings for in situ synthesis of dna arrays
发明人：MCGALL GLENN
权利人:CENTRILLON TECH HOLDINGS CORPORATION
摘要:The present disclosure relates to processes for derivatizing a surface of a substrate with a covalently bonded thin film of hydroxalkylated poly(acrylamide) as a platform for the synthesis of a biomolecule array. These processes can also be used to prepare a surface of a substrate for an in situ solid-phase synthesis of biomolecule array.

专利号:US-2024024497-A1
优先权日:2020-08-06
标 题:Methods for the synthesis of protein-drug conjugates
发明人：BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
权利人:CIDARA THERAPEUTICS INC
摘要:The present invention relates to methods for the synthesis of conjugates useful for the treatment of viral infections, e.g., conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir or an analog thereof) linked to an Fc domain monomer.

专利号:US-9802890-B2
优先权日:2006-02-21
标 题 :Processes for the convergent synthesis of calicheamicin derivatives
发明人：MORAN JUSTIN KEITH; GU JIANXIN
权利人:WYETH LLC
摘要:This invention describes processes for the convergent synthesis of calicheamicin derivatives, and similar analogs using bifunctional and trifunctional linker intermediates.

专利号:US-11149301-B2
优先权日:2017-03-17
标 题 :Preparation of universal spin-coatable amine-reactive surface coatings for biomolecule array fabrication
发明人：MCGALL GLENN
权利人:CENTRILLION TECH HOLDINGS CORP
摘要:The present disclosure relates to processes for derivatizing a surface of a substrate with a covalently bonded thin film of poly(methylsilsesquioxane)-bonded polymers as a platform for the synthesis of a biomolecule array. These processes can also be used to prepare a surface of a substrate for an in situ solid-phase synthesis of biomolecule array.

专利号:US-9469850-B2
优先权日:2007-01-18
标 题 :Oligosaccharides comprising an aminooxy group and conjugates thereof
发明人：ZHU YUNXIANG; CHENG SENG H; JIANG CANWEN; AVILA LUIS Z
权利人:GENZYME CORP
摘要:The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.

专利号:US-2007197455-A1
优先权日:2006-02-21
标 题:Processes for the convergent synthesis of calicheamicin derivatives