CAS: 20431-81-6; Rel-(1R,2R)-2-(Methylamino)Cyclohexanol

该化合物是一种有机化合物,其特点是环己氨醇结构在第二个位置上经过甲基氨基组的修改,该化合物的颜色一般为无色,可粉色黄色液体或固体,视其纯度和温度而定;它既有酒精,也有矿物质功能组,有助于其反应性和氢联结潜力;甲基氨基化合物的存在增加了其在极地溶剂中的溶解性,使其在各种化学应用中有用,包括作为合成药物和农用化学物的中间体;该化合物的分子结构允许潜在的立体异构体主义,可影响其生物活动;此外,2-(甲基氨基)环氧醇可能具有中度挥发性,并具有独特的气味,根据浓度和环境条件而不同,这些特性可能不同;在处理和储存时,应参考安全数据,因为具有矿物质特性的化合物对湿度敏感,可能需要具体的防范措施.

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477584-30-8 51925-39-4 145166-06-9

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上下游产品

cyclohexane-1,2-epoxide methylamine trans-2-chlor°Cyclohexanol trans-2-is°Cyano-1-cyclohexanol (1R,2R)-trans-2-(N-methyl)amino-1-cyclohexanol trans-2-(methylamino)cyclohexanol cis-2-(N-methyl)amino-1-cyclohexanol N-(trans-2-hydroxy-cyclohexyl)-N-methyl-benzamide(+/-)-N-(trans-2-hydroxy-cyclohexyl)-N-methyl-benzamide

合成工艺路线路线简述

    📜(1R,2R)-2-Chlorocyclohexanol 反应生成(1S,2R)-2-甲氨基环己醇
    参考文献:Kovar; Blaha,Collection Of Czechoslovak Chemical Communications,1959,Vol. 24,P. 797,801
    标题:Kovar; Blaha,Collection Of Czechoslovak Chemical Communications,1959,Vol. 24,P. 797,801

    海关参考信息

    专利信息


    专利号:US-5959099-A
    优先权日:1997-03-03
    标 题 :Protecting group for synthesizing oligonucleotide analogs
    发明人：CHERUVALLATH ZACHARIA S; CAPALDI DANIEL C; RAVIKUMAR VASULINGA T; COLE DOUGLAS L
    权利人:ISIS PHARMACEUTICALS INC
    摘要:A 2-N-amidoethyl protected nucleoside analog phosphoramidite of formula (1): ##STR1## is useful in the synthesis of a wide variety of oligonucleotide analogs. Coupling yields with phosphoramidite (1) in solution or solid phase oligonucleotide analog synthesis are high and the 2-N-amidoethyl protecting group can be removed easily under standard conditions.

    专利号:US-6642264-B1
    优先权日:1999-04-06
    标 题 :Thiazolobenzoimidazole derivatives
    发明人：HAYASHIBE SATOSHI; ITAHANA HIROTSUNE; OKADA MASAMICHI; KOHARA ATSUYUKI; MAENO KYOICHI; YAHIRO KIYOSHI; SHIMADA ITSURO; TANABE KAZUHITO; NEGORO KENJI; KAMIKUBO TAKASHI; SAKAMOTO SHUICHI
    权利人:YAMANOUCHI PHARMA CO LTD
    摘要:This invention relates to novel thiazolo[3,2-a]benzoimidazole derivatives represented by the following general formula (I). The compounds provided by the invention act specifically on metabotropic glutamate receptors and are used as medicaments. The invention also provides novel compounds useful as intermediates for the synthesis of the compounds of the invention.(Symbols in the formula represent the following meanings. R<1>: carbamoyl, carbonyl, oxy, amino, carbonylamino or the like which may be substituted; R<2>: hydrogen, lower alkyl or the like; and R<3>, R<4 >and R<5>: hydrogen, lower alkyl and the like which may be the same or different from one another.)

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    合成参考文献


    参考文献:10.1007/978-3-642-77460-7_11
    摘要:Archer S. Chemistry of Nonpeptide Opioids. 1993. In: Opioids. : Springer Berlin Heidelberg; 1993.
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