CAS: 190849-64-0; (Benzotriazol-1-Yloxy)Dipiperidinocarbenium Hexafluorophosphate
- 英文名称(Benzotriazol-1-Yloxy)Dipiperidinocarbenium Hexafluorophosphate
- 中文名称HBPipU(苯并三氮唑-1-基氧基)二哌啶碳六氟磷酸盐
- IUPAC名称1-(((1H-benzo[d][1,2,3]triazol-1-yl)oxy)(piperidin-1-yl)methylene)piperidin-1-ium hexafluorophosphate(V)
- 其它别名(苯并三氮唑-1-基氧基)二哌啶碳六氟磷酸盐(Hbpipu); O-(Benzotriazol-1-Yloxy)Dipiperidinocarbeniumhexafluorophosphate
- CAS编号190849-64-0
- MFCD编号:MFCD00191769
- EINECS号:625-076-8
- 分子式:C17H24F6N5OP分子量:459.38
- 产品CID: 965606
- 产品分类有机原料→通用试剂→缩合反应&活性酯化反应
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专利信息
专利号:US-2025101006-A1
优先权日:2022-01-31
标题:Process for the synthesis of pyrazolyl derivatives useful as anti-cancer agents
发明人：BAENZIGER MARKUS; GALLOU FABRICE; GUO FENGFENG; HÄNGGI RUDOLF; HAN ENJIAN; JORDINE GUIDO; LI JIALIANG; LIU WEIPENG; MIAO BUKEYAN; RONG SHAOFENG; SANTANDREA ERNESTO; SCHIRNER PAUL BERND; SHEN XIAODONG; WANG CAN; ZHANG HAO
权利人:NOVARTIS AG
摘要:The invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially KRAS G12C inhibitors. The present invention provides a direct enantioselective chemical manufacturing method of making Compound A, or a pharmaceutically acceptable hydrate or solvent thereof: (I). The invention provides a process for preparing Intermediate B6* comprising reacting Intermediate B4* with Intermediate B5* in an atroposelective coupling reaction, using a chiral catalyst.
专利号:US-2022233673-A1
优先权日:2019-06-04
标 题:METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF
发明人：BILLET ANNE; SCHMIDT FRÉDÉRIC; JOHANNES LUDGER; SERVENT DENIS; MOURIER GILLES; TARTOUR ÉRIC; KAY MICHAEL; FULCHER JAMES M
权利人:INST CURIE; CENTRE NAT RECH SCIENT; INST NAT SANTE RECH MED; COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES CEA; APHP ASSIST PUBLIQUE HOPITAUX DE PARIS; UNIV PARIS; UNIV OF UTAH RESEARCH FOUDATION; UNIV UTAH RES FOUND
摘要:A method of producing a monomer of a Shiga toxin B-subunit (STxB) protein or of a variant thereof by peptide chemical synthesis, as well as to a method of producing a pentamer of the STxB protein or of the variant thereof. The methods are particularly advantageous as they overcome major issues typically observed in peptide chemical synthesis, including solubility and purity issues.
专利号:WO-2023143605-A1
优先权日:2022-01-31
标 题:Process for the synthesis of pyrazolyl derivatives useful as anti-cancer agents
专利号:CN-115109118-A
优先权日:2021-03-19
标 题:A kind of method for solid-phase synthesis of DS-8201 intermediate and preparation method of DS-8201
专利号:EP-4472969-A1
优先权日:2022-01-31
标 题 :Process for the synthesis of pyrazolyl derivatives useful as anti-cancer agents
专利号:CN-118871436-A
优先权日:2022-01-31
标 题 :Synthesis of pyrazolyl derivatives useful as anticancer agents
