CAS: 13190-97-1; (2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-Nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-Nonaen-1-Ol

相似化合物

106-24-1 106-25-2 24034-73-9

上下游产品

CAS号105-87-3 乙酸香叶酯 | CAS号37905-04-7 acetic acid,8-b... | CAS号37905-03-6 (E,E)-8-acetoxy... | CAS号37905-02-5 (2E,6E)-3,7-二甲基... | CAS号53254-60-7 (E)-1-((3,7-二甲基... | CAS号73127-51-2 (2E,6E,10E)-3,7... | CAS号71816-56-3 (2E,6E,10E)-3,7... | CAS号50848-64-1 geranyl geranyl... | CAS号24034-73-9 香叶基香叶醇 | CAS号24529-80-4 acetic acid,4-c... | CAS号303-98-0 辅酶Q10 | CAS号523-39-7 维生素K2(45)(MK-9) | CAS号303-97-9 辅酶Q9 | CAS号5677-54-3 ubiquinol-9 | CAS号52610-77-2 溴化茄尼酯

香叶基香叶醇置于吡啶,氢氧化钾,正丁基锂,水,三溴化磷,Lithium,乙胺体系中,用 乙醚,N,N-二甲基甲酰胺 用作溶剂,化学反应 31.0H,反应生成茄尼醇
参考文献:茄尼醇和全反式癸酸酚的立体选择性合成
标题:茄尼醇和全反式癸酸酚的立体选择性合成
摘要:烯丙基对甲苯基砜(5),(14)和(16)与烯丙基溴(7)和香叶基溴结合,生成区域和立体化学纯的1,5-二烯体系.全反式-ω-溴香叶基乙酸酯(7)与香叶基对甲苯基砜(5)和高级异戊二烯(21),(24)和(27)偶联,然后还原性消除对甲苯磺酰基,得到全反式聚戊烯醇(3),(23),(26)和癸癸酚(1B)的立体选择性合成.用反式-4-氯异戊烯基乙酸酯(29)代替(7)合成了茄尼醇(1A ).
Doi:10.1039/p19810000761

专利信息

专利号:US-11912654-B2
优先权日:2021-09-03
标 题:Process for stereospecific synthesis of vitamin K2 and its novel intermediates
发明人：MEHTA DILIP; SHASHTRI MAYANK; RAJU BNS; SHAH ASHWIN; VORA PARIN; MAHALE UMAKANT
权利人:SYNERGIA LIFE SCIENCES PVT LTD
摘要:The present disclosure relates to a novel process for the synthesis of stereospecific compounds of Vitamin K2 group in general and Vitamin K2-7. The present disclosure further discloses novel intermediates useful in the synthesis of stereospecific Vitamin K2-7. Compounds of the Vitamin K2 group obtained are crystalline and exhibit well defined melting points.

专利号:WO-2023031841-A1
优先权日:2021-09-03
标题:A process for the stereospecific synthesis of vitamin k2 and its intermediates
发明人：MEHTA DILIP; SHASHTRI MAYANK; RAJU BNS; VORA PARIN; MAHALE UMAKANT
权利人:SYNERGIA LIFE SCIENCES PVT LTD
摘要:The present disclosure relates to a novel process for the synthesis of stereospecific compounds of Vitamin K2 group in general and Vitamin K2-7, in particular. It also discloses novel intermediates useful in the synthesis of stereospecific Vitamin K2-7. Compounds of the Vitamin K2 group obtained are crystalline and exhibit well defined melting points.

专利号:US-2008086013-A1
优先权日:2006-06-15
标 题:Carbometallation of alkynes and improved synthesis of uniquinones
发明人：LIPSHUTZ BRUCE H
权利人:UNIV CALIFORNIA
摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

专利号:US-2007260076-A1
优先权日:2003-12-05
标 题:Practical, Cost-Effective Synthesis of Ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
权利人:LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-2006167289-A1
优先权日:2003-12-05
标题 :Practical, cost-effective synthesis of ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SCHEIN KARIN; WETTERICH FRANK
权利人:ZYMES LLC
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-4061660-A
优先权日:1975-09-29
标 题 :Process for synthesis of coenzyme Q compounds
发明人：KIJIMA SHIZUMASA; YAMATSU ISAO; MINAMI NORIO; INAI YUICHI
权利人:EISAI CO LTD
摘要:A process for the synthesis of 2,3-dimethoxy-5-methyl-6-substituted-1,4-benzoquinones having the formula: ##STR1## wherein R is ##STR2## in which n is an integer of 0 to 9, and A and B are hydrogens or A--B is a direct valence bond between the carbon atoms to which they are attached, n Characterized by reacting 2-methyl-4,5,6-trimethoxyphenol with an aryl boronic acid, a lower alkyl boronic acid or an acid anhydride thereof to obtain a 2-methyl-4,5,6-trimethoxyphenol ester of boric acid, reacting the resulting ester with an n-prenol or iso-prenol having the formula: ##STR3## wherein R is as defined above, OR A REACTIVE DERIVATIVE OF SAID N- OR ISO-PRENOL, IN THE PRESENCE OF A SILICA-ALUMINA COMPOUND, TO OBTAIN A 2-METHYL-3-SUBSTITUTED-4,5,6-TRIMETHOXYPHENOL ESTER OF BORIC ACID, AND HYDROLYZING THE THUS-OBTAINED ESTER AND TREATING THE RESULTING 2-METHYL-3-SUBSTITUTED-4,5,6-TRIMETHOXYPHENOL HAVING THE FORMULA: ##STR4## wherein R is as defined above, WITH AN OXIDIZING AGENT.