CAS: 106120-04-1; 5-Bromobenzene-1,3-Diol

相似化合物

6751-75-3 16492-75-4 6626-15-9

上下游产品

CAS号20469-65-2 1-溴-3,5-二甲氧基苯 | CAS号1132-21-4 3,5-二甲氧基苯甲酸 | CAS号17213-57-9 3,5-二甲氧基苯甲酰氯 | CAS号855400-66-7 3-溴-5-甲氧基苯酚 | CAS号16618-68-1 3-溴-5-甲基氧基苯胺

1-溴-3,5-二甲氧基苯置于三溴化硼体系中,用 二氯甲烷 用作溶剂,化学反应 19.0H,反应生成5-溴-1,3-苯二酚
参考文献:手性 Dmap 衍生物对环状内消旋 1,3-二醇的酰基化去对称化
标题:手性 Dmap 衍生物对环状内消旋 1,3-二醇的酰基化去对称化
摘要:通过使用具有 1,1'-联萘单元的手性 Dmap 衍生物 1E,开发了一种有效的环状内消旋 1,3-二醇的对映选择性酰化去对称化.反应只需要 0.5 M...
Doi:10.1246/cl.200809

专利信息

专利号:US-8178559-B2
优先权日:2004-12-30
标 题:Organic compounds
发明人：BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI
权利人:BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula (I), wherein the symbols have the meanings defined in the specification.