CAS: 776-41-0; Ethyl 1H-Indole-3-Carboxylate

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CAS号771-50-6 吲哚-3-甲酸 | CAS号75-03-6 碘乙烷 | CAS号623-47-2 丙炔酸乙酯 | CAS号64-17-5 乙醇 | CAS号623-73-4 重氮乙酸乙酯 | CAS号529-23-7 邻氨基苯甲醛 | CAS号586-96-9 亚硝基苯 | CAS号552-89-6 邻硝基苯甲醛 | CAS号615-43-0 2-碘苯胺 | CAS号4769-96-4 6-硝基吲哚 | CAS号32387-21-6 1-甲基-3-吲哚酸 | CAS号27393-79-9 1H-indol-3-yl(p... | CAS号10242-03-2 6-硝基吲哚-3-羧酸 | CAS号15317-58-5 吲哚-3-甲酰肼 | CAS号17826-05-0 5,6-二溴吲哚啉-2,3-二酮 | CAS号56559-61-6 ethyl 1-benzyli... | CAS号56559-62-7 1-甲基-1H-吲哚-3-碳酰肼

专利信息

专利号:EP-1836163-B1
优先权日:2004-12-23
标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
发明人：BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
权利人:NOVARTIS AG
摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

专利号:CN-112239468-B
优先权日:2019-07-19
标题 :Metal-free solvent-free synthesis of fused pyridine heterocycles and biomedical applications thereof

专利号:US-2008200475-A1
优先权日:2005-03-28
标题:4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: (I) wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , R 2a , R x , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:CN-105622486-A
优先权日:2015-09-28
标题:A class of bis-indolylmethane compound and its synthesis method and application

专利号:US-8013153-B2
优先权日:2006-03-23
标 题:Substituted pyrimidine kinase inhibitors
发明人：BUTLER JEANNENE; CONNOLLY PETER J; FUENTES-PESQUERA ANGEL R; GREENBERGER LEE M; HUANG SHENLIN; LAMONTAGNE JR KENNETH R; LI RONGHUA; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present invention is directed to substituted pyrimidine compounds of formula (I): n nand forms thereof, their synthesis and use for treating a chronic or acute protein kinase mediated disease, disorder or condition.