CAS: 612-61-3; 7-Chloroquinoline

该化合物是一种有机化合物,其特点是一种有基质结构的有机化合物,在7点方位上将氯原子替换为替代的氯原子,它看起来像是黄色至褐色的灰色固体,以其芳香特性而著称,有助于其稳定性和反应性.该化合物的分子分子式为C9H6ClN,其双循环结构中含有氮原子,这是五氯乙烯的典型特征.7-Croloquinoline主要用于合成各种药品和农用化学品,因为它的生物活动,包括抗微生物和抗疟疾特性.该化合物还被用作较复杂的分子的建筑块.该化合物在有机溶剂中可中中中溶,但水溶性有限.在处理7氯quinoline时,应当采取安全防范措施,因为它可能构成健康风险,包括潜在的毒性.适当的储存和处置方法对于减轻环境影响和确保实验室环境的安全至关重要.

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86-98-6 635-27-8 611-35-8

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合成工艺路线路线简述

    📜4-Chlorocinnamaldehyde置于氢氧化钾体系中,用 乙醇 作为反应溶剂,650.0 °C,1.33 Pa 条件下,反应 0.75H,反应生成 7-氯喹啉
    参考文献:Hickson,Clare L.; Mcnab,Hamish,Journal Of The Chemical Society. Perkin Transactions I,1984,# 7,P. 1569-1572
    标题:Hickson,Clare L.; Mcnab,Hamish,Journal Of The Chemical Society. Perkin Transactions I,1984,# 7,P. 1569-1572

    海关参考信息

    专利信息


    专利号:US-2007060558-A1
    优先权日:2004-07-30
    标 题 :Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents
    发明人:SANCHEZ MURIEL; MEUNIER BERNARD
    权利人:CENTRE NAT RECH SCIENT
    摘要:The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q—(Y 1 ) p —(U) p —(Y 2 ) p -A: wherein Q represents an aminoquinoline, (Y 1 ) p (U) p —(Y 2 ) p″ is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.

    专利号:US-7786138-B2
    优先权日:2005-11-18
    标题 :Process for making montelukast and intermediates therefor
    发明人:BENOVSKY PETR; THIJS LAMBERTUS; OVEREEM ARJANNE; CASTULIK JAKUB; ZHU JIE; BARTOS PETR; SKOUMAL RADOMIR
    权利人:SYNTHON BV
    摘要:A compound of the following formula n nwherein R′ is a straight or branched C1-C4 alkyl group is useful in processes associated with the synthesis of montelukast and its salts.

    专利号:WO-2008035086-A2
    优先权日:2006-09-22
    标题:Synthesis of leukotriene compounds

    专利号:CN-106928136-B
    优先权日:2017-02-23
    标题:A kind of method of graphene palladium cobalt sequential catalyst synthesis montestron sodium intermediate

    专利号:CN-109485667-B
    优先权日:2018-12-24
    标 题 :Synthesis method of 2-aryl-tetrahydroquinoline-4-boron ester compound

    专利号:CN-101712688-A
    优先权日:2004-07-30
    标题 :Q is an aminoquinoline and A is a hybrid QA molecule of an antibiotic residue, its synthesis and antibacterial agent application

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 66.
    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 89.
    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 73.
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