CAS: 5503-41-3; Rhodium(Ii) Acetate

专利信息

专利号:US-4287123-A
优先权日:1980-01-14
标题 :Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate
发明人：LIU THOMAS M H; MELILLO DAVID G; RYAN KENNETH M; SHINKAI ICHIRO; SLETZINGER MEYER
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: II wherein R is a readily removable carboxyl protecting group; and is a readily removable acyl group.

专利号:US-4282148-A
优先权日:1980-01-14
标 题:Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid
发明人：LIU THOMAS M H; MELILLO DAVID G; RYAN KENNETH M; SHINKAI ICHIRO; SLETZINGER MEYER
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: II wherein R3 is a readily removable carboxyl protecting group.

专利号:US-4269772-A
优先权日:1980-01-14
标 题 :Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-Δ2 -isoxazoline
发明人：MELILLO DAVID G; RYAN KENNETH M
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: II wherein R5 and R6 are removable protecting groups.

专利号:US-4349687-A
优先权日:1980-01-14
标 题:Intermediate for synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid
发明人：LIU THOMAS M H; MELILLO DAVID G; RYAN KENNETH M; SHINKAI ICHIRO; SLETZINGER MEYER
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin via intermediates II and IIa: II IIa wherein R is a readily removable carboxyl protecting group.

专利号:US-4473502-A
优先权日:1981-04-08
标题 :Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid
发明人：LIU THOMAS M H; MELILLO DAVID G; RYAN KENNETH M; SHINKAI ICHIRO; SLETZINGER MEYER
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin via intermediates II and IIa: wherein R is a readily removable carboxyl protecting group.

专利号:US-2023357257-A1
优先权日:2020-12-28
标 题 :Novel process for the synthesis of noroxymorphone from morphine
发明人：GORBACHEV DMITRY; LAM HON WAI; SAXENA AAKARSH; SAXENA NAVIN SATYAPAL
权利人:NAVIN SAXENA RESEARCH & TECH PVT LTD
摘要:The present invention relates to a novel, efficient, pot- and atom-economical, and industrially applicable process for converting morphine to noroxymorphone using reagents and solvents of lesser toxicity and lower cost with respect to those used in the prior art.