CAS: 401-80-9; 3-Fluorobenzotrifluoride

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CAS号98-16-8 间三氟甲苯胺 | CAS号98-46-4 间硝基三氟甲苯 | CAS号373-91-1 三氟甲基次氟酸酯 | CAS号98-08-8 三氟甲苯 | CAS号32890-94-1 2-氟-6-(三氟甲基)苯甲酸 | CAS号1493-13-6 三氟甲烷磺酸 | CAS号454-87-5 tetrafluorobora... | CAS号141179-72-8 4-氟-2-(三氟甲基)苯甲酸 | CAS号76-05-1 三氟乙酸(TFA) | CAS号462-06-6 氟苯 | CAS号60611-24-7 2-氟-6-(三氟甲基)苯甲醛 | CAS号90176-80-0 4-氟-2-三氟甲基苯甲醛 | CAS号352-70-5 3-氟甲苯 | CAS号32890-94-1 2-氟-6-(三氟甲基)苯甲酸 | CAS号401-77-4 3-氟三氯甲苯 | CAS号393-39-5 2-氨基-5-氟三氟甲苯 | CAS号393-09-9 5-氟-2-硝基三氟甲苯 | CAS号393-38-4 2,5-二氟三氟甲基苯 | CAS号39234-83-8 4-硝基-3-(三氟甲基)苯磺酰氯 | CAS号146137-87-3 4-(三氟甲基)苯并[b]噻吩...

三氟甲苯置于二氟代氙,氢氟酸体系中,用 四氯化碳 作为反应溶剂,化学反应生成 3-氟三氟甲苯
参考文献:芳族化合物与二氟化氙的反应
标题:芳族化合物与二氟化氙的反应
摘要:在弱酸性(1,1,1,3)中,在三氟化硼-乙醚络合物的存在下,取代苯的c 6 H 5 R(r = Me,F,Cl,Br,Cf 3,No 2)与二氟化氙的反应,3-五氟丁烷)和弱碱性介质(乙腈)已被研究.这些反应导致氟苯衍生物fc 6 H 4 R(异构体混合物)与异构二氟苯以及氟化和非氟化联苯一起形成.将结果与先前报道的使用其他催化剂在其他溶剂中获得的数据进行了比较.
DOI:10.1134/s1070428016100055

专利信息

专利号:US-6403793-B2
优先权日:2000-06-12
标 题 :Intramolecular glycosidation process for the synthesis of (2R, 2-alpha-R, 3a)-2-[1-(3,5- bis (trifluoromethyl) phenyl)ethoxy]-3-(4-fluorophenyl)-1,4-oxazine
发明人：PYE PHILIP J; ROSSEN KAI
权利人:MERCK & CO INC
摘要:The present invention is concerned with novel processes for the preparation of (2R-cis)-2-[[1-[3.5-bis(trifluoromethyl)phenyl]ethenyl]oxy]-3-(4-fluorophenyl)-4-(phenylmethyl) mopholine. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:US-6255545-B1
优先权日:1999-06-11
标 题 :Process for the synthesis of 3,5-bis(trifluoromethyl)-bromobenzene
发明人：CVETOVICH RAYMOND; TSAY FUH-RONG
权利人:MERCK & CO INC
摘要:The present invention is concerned with a novel process for the preparation of 3,5-bis(trifluoromethyl)bromobenzene (CAS 328-70-1). This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:US-6350915-B1
优先权日:1999-06-11
标 题:Process for the synthesis of 1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-one
发明人：CVETOVICH RAYMOND
权利人:MERCK & CO INC
摘要:The present invention is concerned with a novel process for the preparation of 1-(3,5-bis(trifluromethyl)phenyl)ethan-1-one (CAS 30071-93-3). This compound is useful as an intermediate in the synthesis of therapeutic agents.

专利号:US-6395898-B1
优先权日:2000-06-09
标 题:Trans-glycosidation process for the synthesis of (2R, 2-alpha-R, 3a)-2-[1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-1,4-oxazine
发明人：MCNAMARA JAMES M; ZHAO MATTHEW M
权利人:MERCK & CO INC
摘要:The present invention is concerned with novel processes for the preparation of (2R, 2-alpha-R, 3a)-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-3-(4-fluorophenyl)-1,4-oxazine. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:US-2013184465-A1
优先权日:2010-09-30
标 题:Process for the synthesis of thio-triazolo-group containing compounds
发明人：DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

专利号:US-7842834-B2
优先权日:2005-07-21
标 题:Process for the synthesis of sulfonyl halides and sulfonamides from sulfonic acid salts
发明人：MICHALAK RONALD S; HELOM JEAN L; ZELDIS JOSEPH
权利人:WYETH LLC
摘要:The present invention provides synthetic processes for the preparation of sulfonyl halides of Formula Ar—(R) z —SO 2 —X and sulfonamides of Formula Ar—(R) z —SO 2 —NR 4 R 5 , where the constituent variables are as defined herein, that are useful as intermediates in the preparation of pharmaceuticals.