CAS: 3391-10-4; 1-(4-Chlorophenyl)Ethanol

该化合物是一种有机化合物,其特点是存在一个附属于乙醇协会的氯联苯集团,该化合物一般是淡黄色液体的无色物质,具有温和的沸点,表明其分子重量和结构,可溶于乙醇和乙醚等有机溶剂,但由于其含氢恐惧的氯联苯集团,其溶解性有限.氢氧(OH)基(HI)基乙醇的存在有助于其再活性,使其得以参与各种化学反应,包括氧化和酯化.此外,氯联苯替代成分可影响该化合物的生物活动,使其对制药和农用化学研究感兴趣.安全数据表明,应谨慎处理该物质,因为它可能会对接触化学品造成健康风险.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

methyl magnesium iodide 4-chlorobenzaldehyde methylmagnesium bromide sodium ethanolate 1-(4-chloro-phenyl)-1-phenyl-ethanol 1-(4-chlorophenyl)ethyl acetate para-chloroacetophenone 3-(4-chlorophenyl)butanoic acid

合成工艺路线路线简述

    📜对氯苯乙酮置于rubr(η2-Dppm)(Mecoo)(3-Rbzth),异丙醇,Sodium T-Butanolate体系中,化学反应 0.24H,以94%的收率获得1-(4-氯苯基)乙醇
    参考文献:钌(II)n,S-杂环碳二膦配合物的合成,结构及其对转移加氢的催化活性
    标题:钌(II)n,S-杂环碳二膦配合物的合成,结构及其对转移加氢的催化活性
    摘要:[ru Ii Br(mecoo)(pph 3)2(3-Rbzth)](3-Rbzth = 3-苄基苯并噻唑-2-亚基)的膦与一系列二膦(双(二苯基膦基)甲烷(dppm),1,2-双(二苯基膦基)乙烯(dppv),1,1'-双(二苯基膦基)二茂铁(dppf),1,4-双(二苯基膦基)丁烷(dppb)和1,3-(二苯基膦基)丙烷(dppp )),得到单核细胞和中性八面体配合物[rubr(mecoo)(η 2-P 2)(3-Rbzth)](p 2 = Dppm(2),Dppv(3),Dppf(4),Dppb(5),或dppp(6)),其配位球包含四个不同的配体,即螯合二膦,羧酸盐,N,S-杂环卡宾(nshc)和溴化物.已分离出两个6(6A和6 B)的几何异构体.这些产品的结构(已通过单晶x射线晶体学阐明)显示出两种结构类型,即i和ii,具体取决于配体的相对位置.I型结构包含向氧原子反式的碳原
    Doi:10.1002/asia.201000930

    海关参考信息

    专利信息


    专利号:US-7579294-B2
    优先权日:2004-12-29
    标题:Synthesis of supported transition metal catalysts
    发明人:PARK JAIWOOK; KIM NAMDU; KWON MIN SERK; PARK CHEON MIN
    权利人:POSTECH FOUNDATION
    摘要:A highly active and recyclable supported transition metal catalyst can be prepared by a simple process comprising mixing with heating a transition metal complex, a metal-chelating agent and an alkoxide of Ti, Al or Si, followed by treatment with water to induce a sol-gel reaction among the reactants.

    专利号:US-2009137385-A1
    优先权日:2004-12-29
    标 题 :Synthesis of supported transition metal catalysts

    专利号:WO-2023086799-A1
    优先权日:2021-11-09
    标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists
    发明人:HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P
    权利人:VIGIL NEUROSCIENCE INC
    摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

    专利号:US-4346242-A
    优先权日:1980-06-05
    标 题:Method for preparing substituted meta-phenylalkoxynitrobenzenes
    发明人:SPATZ DAVID M
    权利人:AMERICAN CYANAMID CO
    摘要:Methods for the preparation of substituted meta-phenylalkoxynitrobenzenes and their use as starting materials for the synthesis of herbicidal meta-phenylalkoxyphenylurea.

    专利号:US-2020384451-A1
    优先权日:2017-09-05
    标题:Phosphine free cobalt based catalyst, process for preparation and use thereof
    发明人:BALARAMAN EKAMBARAM; MIDYA SIBA PRASAD; LANDGE VINOD GOKULKRISHNA
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention discloses a phosphine free cobalt based catalyst of formula (I) and a process for preparation thereof. The present invention further discloses a process for the synthesis of aromatic heterocyclic compounds of formula (II) and pyrazine derivative using the phosphine free cobalt based catalyst of formula (I).

    专利号:CN-1608076-A
    优先权日:2001-10-25
    标题 :Synthesis of 2-aralkyloxyadenosine and 2-alkoxyadenosine

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Lipshutz, B. H.; Ghorai, S., Science of Synthesis Knowledge Updates, (2014) 2, 178.
    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 85.
    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 346.
    摘要:Kawęcki, R., Science of Synthesis Knowledge Updates, (2018) 4, 251.
    摘要:Brown, J. M.; Nguyen, B. N., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 306.
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