CAS: 230615-52-8; 2,3,4,5-Tetrahydro-1H-1,5-Methanobenzo[d]Azepine Hydrochloride

上下游产品

CAS号230615-48-2 2,3,4,5-四氢-3-苄基... | CAS号230615-51-7 2,3,4,5-四氢-3-(三...

1,3-Dibromo-Indan-2-One置于盐酸,Sodium Tetrahydroborate,水,乙酸酐,Potassium Hydroxide体系中,用 四氢呋喃,甲醇,乙醇,水 用作溶剂,化学反应 23.0H,反应生成2,3,4,5-四氢-1,5-甲桥-1H-3-苯并氮杂卓盐酸盐
参考文献:一种伐伦克林关键中间体的制备方法
标题:一种伐伦克林关键中间体的制备方法
摘要:本发明公开了一种伐伦克林关键中间体的制备方法,以茚酮为原料,经过卤代,氰化,水解,闭环反应,还原及成盐酸盐六步反应,得到目标化合物.采用本发明的制备方法,原料易得,反应条件温和,工艺简单,收率高,成本较低,对环境污染小,在工业生产中有很好的利用价值.

专利信息

专利号:US-7205300-B2
优先权日:1997-12-31
标 题:Aryl fused azapolycyclic compounds
发明人：COE JOTHAM WADSWORTH; BROOKS PAIGE ROANNE PALMER
权利人:PFIZER
摘要:This invention is directed to compounds of the formula (I): n nand their pharmaceutically acceptable salts, wherein R 1 , R 2 , and R 3 are as defined herein; intermediates for the synthesis of such compounds, pharmaceutical compositions containing such compounds; and methods of using such compounds in the treatment of neurological and psychological disorders.